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   2003| January-February  | Volume 69 | Issue 1  
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Treatment of schamberg's disease with pentoxifylline - therapeutic trial
V Gandhi, A Singal, B Sachdeva, SN Bhattacharya
January-February 2003, 69(1):25-26
Twenty patients with Schamberg's disease were started on pentoxifylline (400 mg once daily) for a period of 8 weeks. Improvement was assessed at 2 weekly intervals by two observers independently and graded as mild (<25%, moderate (25-50%) and marked (>50%). Marked improvement was observed in 10/20(50%) patients. We conclude that pentoxifylline should be considered as first line therapy in all patients with Schamberg's disease
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Comparative evaluation of clindamycin phosphate 1% and clindamycin phosphate 1% with nicotinamide gel 4% in the treatment of acne vulgaris
SK Dos, JN Barbhuiya, S Jana, SK Dey
January-February 2003, 69(1):8-9
Eighty patients with moderate acne vulgaris were enrolled from out-patient department for the comparative evaluation of clindamycin phosphate 1% and clindamycin phosphate 1% with nicotinamide gel 4%. In group I forty patients were given clindamycin phosphate 1% alone.ln group II forty patients were given clindamycin phosphate 1% and nicotinamide gel 4% in combination. The study did not show any added advantage of clindamycin phosphate 1% in combination with nicotinamide gel 4% over clindamycin phosphate 1 % alone.
  24,630 12 2
Parakeratosis pustulosa - a distinct but less familiar disease
Deepika Pandhi, S Chowdhry, C Grover, B SN Reddy
January-February 2003, 69(1):48-50
Parakeratosis pustulosa (PP) is a distinct but less commonly known skin disease, which is frequently seen, in young girls. We describe the clinical and histological features of PP in a 7 month old female baby. Further, it is stressed that unless carefully looked for, this entity may be easily misdiagnosed as chronic paronychia, acrodermatitis of Hallopeau, pustular psoriasis, atopic dermatitis, tinea pedis or dry fissured eczematoid dermatitis and mistreated subsequently.
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Cutaneous manifestations of non-hodgkin's lymphoma
S Sathish Kumar, Maria Kuruvilla, Ganesh S Pai, M Dinesh
January-February 2003, 69(1):12-15
Thirty-two confirmed cases of non -Hodgkin's lymphoma (NHL) were examined for cutaneous manifestations for a period of 2 years from November 1998 in KMC Hospital Attavar, Mangalore. Cutaneous manifestations in the study group were compared to a control group of 32 patients. Specific infiltrates were present in all (5/5) CTCL patients and one out of twenty-seven patients with low grade NHL. Morphologically they presented as papules, plaques, nodules and erythroderma. Infective conditions seen in the study group were superficial fungal (7/32) and viral infections (2/ 32). Non-infective conditions were acquired ichthyosis (10/32), generalised pruritus (5/32), insect bite reaction (1/32) and drug eruption (1/32). When compared to control patients only acquired ichthyosis and generalised pruritus were found to be statistically significant. The study group also showed changes due to chemotherapy like diffuse alopecia (24/29), bluish pigmentation of proximal part of nail (4/29), localised pigmentation of palms and soles (1 /29), diffuse pigmentation at injection site (1 /29), pigmentation at scar site (1 /29) and stomatitis (4/29).
  11,494 8 3
Multicenter study to evaluate efficacy and irritation potential of benzoyl peroxide 4% cream in hydrophase base (Brevoxyl) in acne vulgaris
SN Sawleshwarkar, V Salgaonkar, CM Oberai
January-February 2003, 69(1):19-22
In this multicenter, open, non-comparative study, the efficacy and irritation potential of 4% benzoyl peroxide cream in hydrophase base (Brevoxyl) was evaluated for the treatment of acne vulgaris. All evaluable patients (n=567) received treatment with 4% benzoyl peroxide cream in hydrophase base for six weeks. The investigators evaluated the patients at baseline and at 1,2,4 & 6 weeks. Patients also rated their improvement and adverse effects. Doctor's assessment showed that at the end of 6'h week 85.6% had good to very good effect of the treatment. The profile of side effects observed by doctors revealed that 53.8% of total patients did not have any irritation whereas only 11.6% had moderate to severe irritation. 53.8% of patients did not report any irritation: 41.4% had some irritation whereas only 4.8% patients reported troublesome irritation. A satisfactory response was reported as ear;y as two weeks and most of the patients had a very satisfactory response after six weeks and were willing to continue the treatment. This supports the theory that the hydrophase formulation in 'Brevoxyl helped to enhance efficacy and decrease the irritation associated with use of benzoyl peroxide.
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Contact vitiligo: etiology and treatment
P Singh, J Singh, US Agarwal, RK Bhargava
January-February 2003, 69(1):27-29
Fifty patients of contact vitiligo were studied. EtiologicaI agents of contact vitiligo were identified by clinical history, distribution of lesions and patch testing with suspected material. All patients were advised to avoid the suspected agent and treated with PUVASOL and topical steroid. Out of 50 patients (Male 8%, Female 92% age 14-60 years)., etiological agent of contact vitiligo was found to be sticking bindi alone in 24 (48%), while bindi along with other etiological agents were found to be purse, foot wear, plastic watch strap, lipstick and tooth paste in 14 ( 28%) cases. 14 (28%) patients also had disseminated lesions of vitiligo along with contact vitiligo. Positive reaction with patch testing was observed in 18 (36%) while depigmentation was seen in 4 ( 8%) cases. We observed that response of treatment was better in patients with shorter duration of disease while poor response was seen in patients with longer duration of disease.
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Treatment of pemphigus
C Balachandran
January-February 2003, 69(1):3-5
  9,427 1 3
Hepatic involvement and hepatitis B surface antigen (Hbs Ag) in leprosy
PK Nigam, GB Gupta, A Khare
January-February 2003, 69(1):32-34
Hepatic involvement and hepatitis B surface antigenemia was studied in 80 leprosy patients and results were compared with 50 normal healthy controls. HbsAg was detected in 7.54% of lepromatous leprosy patients as compared to 2% of the normal healthy controls. There was a decrease in albumin and increase in globulin levels with significant decrease in A: G ratio. SGPT levels were significantly raised in lepromatous leprosy patients. Histopathological changes were present in 57.1 % of lepromatous leprosy and 23.8% of tuberculoid leprosy patients.
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Installation of solarium - 2000 for phototherapy
Anuarag Tiwari, CR Srinivas, Mohammed Musthafa, Reena Rai, P Surendran
January-February 2003, 69(1):10-11
Sunlight is the cheapest and most easily available source of ultraviolet light for phototherapy. The disadvantage of using sunlight as the source of ultraviolet light includes its variation with time , place and season, lack of privacy, and atmospheric conditions. To ensure correct dose of UV light in spite of variation in irradiation from the sunlight,we used a PMA2100 meter [Figure:2] and 2110 UVA detector ( Solar light Co, Philadelphia). Privacy for the patients was achieved by erecting a solarium and incidental UVB radiation was cut off by using window glass as the roof of the solarium. We recommend the solarium as a less expensive alternative to artificial phototherapy units, especially in places where there is plenty of sunlight.
  6,965 0 1
Pityriasis rotunda
Iffat Hasson, Parvaiz Shah
January-February 2003, 69(1):50-51
Pityriasis rotunda is described as a persistent, large, sharply defined circular patch of dry ichthyosiform scaling with no inflammatory changes. Here we report a case of pityriasis rotunda in a thirteen year old girl in view of the rarity of the condition.
  6,919 4 -
Calcinosis cutis
VR Sardesai, MB Gharpuray
January-February 2003, 69(1):45-46
A 22-year-old male patient presented with multiple swellings over elbows and knees and a sinus over the right elbow discharging chalky white material. Skin biopsy of the swelling demonstrated calcium deposition in dermis and subcutis. There was no evidence of connective tissue disorder or abnormal mineral metabolism. Hence it was concluded as idiopathic calcinosis cutis and is reported for its interesting presentation.
  6,752 4 1
Multicentric reticulohistiocytosis
AG Rao, T SS Lakshmi, V Vani
January-February 2003, 69(1):35-36
A 41 -year-old man presented with multiple, painful and tender nodules on the palms, soles, scalp; and on the limbs predominantly around the joints with associated arthropathies. Smaller nodules were seen on the ear helices. There was no other clinically evident or investigative abnormality. Histopathologicol study confirmed a diagnosis of multicentric reticulo histiocytosis.
  6,664 0 -
Clinical study of cutaneous drug reactions in 80 patients
S Sehgal, C Balachandran, SD Shenoi
January-February 2003, 69(1):6-7
Eighty patients (46 males, 34 females) with cutaneous drug eruption were studied. Maculopapular rash was the commonest reaction seen in 46 cases, others being purpuro in 7, acneiform in 6, SJS/ TEN in 5, FIDE in 5, EM in 3, exfoliative dermatitis in 2, AEGP in 2, pustular and eczematous reaction in one each. Majority of the patients were in 21-30 year age group, the youngest being 3 years and the oldest 76 years. The incriminated drugs were NSAIDS in 28, antipsychotics in 26, antibiotics in 24, antileprotics / antitubercular in 8, steroids in 5, antimitotics in 4 and cardiac drugs in 3 cases. Histopathologicol features were compatible with the clinical lesions in most of the cases. The commonest immunoreactant in direct immunofluorescence was C3 and fibrin.
  6,631 0 5
Pattern of dermatological diseases in gauhati medical college and hospital Guwahati
KK Das
January-February 2003, 69(1):16-18
A study on 42198 new cases who have attended the Dermatology department of Gawahati Medical College and Hospital, Guwahati, Assam was carried out for a period of 3 years (1998, 1999 and 2000) Eczema (23.10%), pyoderma (14.29%), fungal infection(14.24%) and psoriasis (5.77%) were the major skin diseases in this part of our country. The incidence of S.T.D. and leprosy has been recorded as 2.63% and 2.26% respectively.
  6,423 0 3
Clinicopathological study of exfoliative dermatitis
R Sudho, SB Hussain, E Bellraj, M Frederick, V Mahalaxmi, S Sobhana, S Anandan
January-February 2003, 69(1):30-31
A clinicopathological study of exfoliative dermatitis involving 25 fresh cases was carried out. Males were predominantly affected with a peak incidence between 21-30 years. Pruritus, shivering, erythema and scaling were the common clinical manifestations. Psoriasis and eczema were the most common aetiological factors and the histopathological findings were correlating with the same.
  6,413 0 1
Congenital melanocytic nevus studded with strawberry haemangioma on the scalp
BB Mahajan, A Pall, RR Gupta
January-February 2003, 69(1):40-41
A six-month-old male infant presented with congenital melanocytic nevus (CMN) studded with strawberry haemangioma on the right side of scalp since birth. Both lesions were gradually increasing up to the present size. The case is being reported for its rare occurrence.
  6,258 0 2
Palmo-plantar lichen sclerosus et atrophicus
Kamal Aggarwal, VK Jain, Dora Brahma
January-February 2003, 69(1):43-44
A case of lichen sclerosus et atrophicus (LSA) in a male patient who presented with multiple hypopigmented to depigmented macules, polygonal in shape, distributed in a bilaterally, symmetrical manner over the hands, feet and flexor aspect of wrists is being reported. Histopathology confirmed the diagnosis of LSA.
  6,138 0 -
Verrucous epidermal naevus associated with woolly hair naeves
Shaikh Manzoor, Naseer Ahmed Mir, Seema Qayoom
January-February 2003, 69(1):37-38
An unusual case of verrucous epidermal naevus associated with wooily hair noevus of the scalp is being reported.
  5,596 4 1
Pityriasis rosea unilateralis
BK Brar, A Pall, RR Gupta
January-February 2003, 69(1):42-43
The classical pityriasis rosea presents with erythematous papulosquamous lesions. It has got many clinical and morphological variants. Pityriasis rosea unilateralis is very rare variant of pityriasis rosea. We are reporting two cases of unilateral pityriasis rosea.
  5,355 0 2
HIV seropositivity among patients with sexually transmitted diseases
A Aggarwal, U Arora
January-February 2003, 69(1):23-24
2013 patients with various sexually transmitted diseases were screened for HIV antibodies in voluntary counseling and testing centre (VCTC) attached to Microbiology Lab of Govt. Medical College, Amritsar from Jan. 1998 to Dec. 2001. Sixty-one (3.03%) were found to be positive for HIV. 44 were males and 17 were females. There was a constant rise in the percentage positivity in females from 14.3% in 1998 to 38.09% in 2002. There was also rise in the prevalence of HIV among the STD attenders (1.65% in 1998 to 5.13% in 2001).
  5,221 0 1
Herpes labialis and genitalis in a HIV positive patient. Is it not?
DM Thappa
January-February 2003, 69(1):54-54
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Broom stick dermatitis
K Banerjee, R Banerjee
January-February 2003, 69(1):39-40
Soft plastic handle cover of newly produced broom stick causing contact dermatitis in reported.
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Ecthyma Gangrenosum In a new born child
AM Pandit, B Siddaramappa, SV Choudhary, BS Manjunathswamy
January-February 2003, 69(1):52-53
Ecthyma gangrenosum is one of the most serious and specific cutaneous infection caused by Pseudomonas aeruginosa. We report a case of ecthyma gangrenosum in a new born child who responded poorly to the antipsedomonas treatment to highlight the poor prognosis in new born.
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Cutaneous anthrax of the eyelid
DM Thappa, K Karthikeyan, V Anand Rao
January-February 2003, 69(1):55-55
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Textbook of Dermatology
T Gopinath
January-February 2003, 69(1):54-54
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Current Literature-Dermatology 2000-2001
T Gopinathan
January-February 2003, 69(1):53-53
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Dermatisis herpetiformis and alopecia areata. A rare association in two sisters
Vishaal Madan, Usha Gupta, DK Gupta
January-February 2003, 69(1):46-47
Two sisters each suffering from alopecia areata and dermatitis herpetifomis together simultaneously are reported.
[ABSTRACT]   Full text not available     [PubMed]
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Online since 15th March '04
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