Cutaneous leis hmaniasis is endemic in some regions of Saudi Arabia. A case with uncommon hyperkeratotic type of lesion was seen. Being an endemic zone, a slit- skin smear was done and stained with Giemsa's stain. Smears howed Leishman Donovan bodies within and outside the macrophages. Significant improvement, followed by complete resolution of the lesion was seen with ketoconazole treatment.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]  [PubMed]

Three cases of tuberculosis of the penis are reported. The first two cases were papulonecrotic tuberculids over the glans penis and the third case was tuberculous ulcer of the penis. In the first 2 cases, no focus of tuberculosis infection could be detected. The third case had pulmonary tuberculosis. All our patients responded to treatment with antituberculosis drugs.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]  [PubMed]

Acquired lymphangiectasia can sometimes occur on the vulva and cause diagnostic difficulties especially if they have a warty appearance. We report a case of acquired vulva I lymphangiectasia which mimicked genital warts.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]  [PubMed]

A rare case of ectrodactyly or lobster claw without any other ectodermal involvement is presented. His family history was non - contributory

[ABSTRACT]  [FULL TEXT]    [CITATIONS]  [PubMed]

Papillon- Lefevre syndrome is a disorder of keratinization transmitted probably in an autosomal recessive fashion. Two brothers aged 7 and 4½ years, of this syndrome is reported. Both had polmo - plantar keratoderma, early loss of teeth along with involvement of knees and elbows. There was no history of consanguinity between parents.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]  [PubMed]

Fifteen patients with superficial fungal infections (tinea versicolor -9, dermatophytic infections-6) were included in this study. Skin scrapings were collected directly on to the glass slide and also by using cellophane tape. Both the samples were mounted with KOH. Fungal elements were detected by both the methods in all cases and was better visualised by the tape method.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]  [PubMed]

With an aim to determine minimum erythema dose of narrow band UV-B, 30 subjects, 20 with type IV skin and 10 with type V skin were subjected to graded incremental doses of 311-Narrow band UV-B phototherapy cabiner by Daavlin. Barely perceptible erythema 24 hours after exposure was taken as MED. 33.3% developed erythema at 745mj, 26.6% at 620mj, 23.3% at 1075mj, and 10% at 1290mj. The average MED for narrow band UV-B exposure for type 1V skin was 600mj, [range 5515-755mj] and for type V skin 1100mj{range 8951290mj} Better therapeutic response can be obtained by giving approximately 360-450mj as initial irradiation dose for type 1 V skin and 600-825mj for type V skin.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]  [PubMed]

Woolly hair is tightly coiled hair occurring over the entire scalp or part of it, in an individual of non- Negroid origin. Two such cases occurring in a family is reported due to its rarity.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]  [PubMed]

A case of pyoderma gong re nosum treated initially with sulfasalazine and later with dapsone and being kept in remission with dapsone alone is being reported.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]  [PubMed]

The overlapping clinical features of fixed drug eruption (FDE), Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) make differentiation between them difficult, especially if FDE is multifocal and extensive. We present a case of multifocal bullous FDE mimicking SJS.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]  [PubMed]

Acquired digital fibrokeratoma is a rarely reported disorder, especially in the Indian literature. We report our findings on one such case, occurring at an unusual site.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]  [PubMed]

[FULL TEXT]    [CITATIONS]  [PubMed]

The cutaneous and mucosal pain syndromes are characterized by pain, burning sensation, numbness or paraesthesia of a particular part of the skin or mucosal surface without any visible signs. They are usually sensory disorders, sometimes with a great deal of psychologic overlay. In this article various conditions have been listed and are described. The possible causative mechanisms are discussed when they are applicable and the outline of their management is described.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]  [PubMed]

In an open clinical study, efficacy of 5% aqueous solution of lactate for preventing acne was evaluated IN 22 patients. Lactate lotion was used topically all over the face twice a day and continued like a cosmetic for 1 year. Systematic antibiotics were given for periods of 4 weeks whenever the disease was severe. The effect of the treatment was evaluated by counting the number of comedones, inflammatory lesions and cysts separately once a month and recording them graphically. The greatest reduction in the lesion counts was achieved in 8-24 weeks for the inflammatory lesions and 8-30 weeks for the comedones. At the end of 1 year 90-100% reduction of the inflammatory lesions was achieved in 40.9% patients and non-inflammatory lesions in 22.7% patients. The remaining patients showed 50-90% reduction, while 2 patients showed less than 50% reduction in the non-inflammatory lesions. Thus, most of the patients showed significant reduction in the lesion counts. Aggravations were associated with the hot and the rainy season and required concomitant treatment with oral antibiotics.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]  [PubMed]

The impact of MDT on the prevalence and incidence rate of leprosy was studied in a project area of 1,30,000 population over a period of 14 years, with a special reference to new monolesional cases and those presenting as smear positive cases. The prevalence rate showed a fall from 23 per 10,000 in 1986-87 to 1.33 per 10,000 in 1999-2000. The number of cases presenting with single lesion however showed a downward trend from 63.69% in 1986-87 to 26.09% in 1999-2000. The cases showing smear positivity among the new cases detected showed an ascent from 3.91 % in 1986-87 to 4.35% in 1999-2000 with a peak of 25% in 1995-96. A similar trend was seen in the analysed figures of the 4 general surveys done.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]  [PubMed]

A case of chronic leg ulcer for the last two years in a 50-year-old male, not responding to conventional therapeutic modalities had shown faster healing and excellent cosmetic results by undertaking split skin thickness grafting in the hands of a dermatologist.

[ABSTRACT]  [FULL TEXT]     [PubMed]

A case of hilar lymphadenopathy, a cardinal sign of extra- cutaneous sarcoidosis, is being described in detail. It continued to be a diagnostic dilemma until the appearance of several papules and/or nodules overthe face, front and back of the upper chest. The diagnosis was clinched by demonstration of non-caseating, epithelioid naked granuloma and affirmative response to oral administration of prednisolone in dosage of 40 mg a day.

[ABSTRACT]  [FULL TEXT]     [PubMed]

Bleomycin frequently causes cutaneous toxicity in the form of pigmentary disturbances. We report 2 patients with testiculartumours who developed distinctive "flagellate" pigmentation on trunk and extremities during bleomycin therapy.

[ABSTRACT]  [FULL TEXT]     [PubMed]

A 59 -year-old man developed gradually appearing and slowly progressive tender papulo-nodular lesions in a naevoid distribution on the left side of the trunk since the age of 49 years. The histopathological features were classical of leiomyoma.

[ABSTRACT]  [FULL TEXT]     [PubMed]

A 28-year-old man presented with multicentric lupus vulgaris on keloids over chest, axilla, neck and back for last 6 months. He had pulmonary tuberculosis. All the laboratory investigations were in favour of clinical diagnosis. The patient responded to antituberculosis therapy.

[ABSTRACT]  [FULL TEXT]     [PubMed]

An unusual form - large linear lobulated-of naevus sebaceous on the ear is reported in a 40-year-old man. It simulated syringocystadenoma papillitferum clinically.

[ABSTRACT]  [FULL TEXT]     [PubMed]

A 25- year -old male had accessory auricles at birth and developed ectopic digit since 1 year. As this association could not be traced in literature, it is being reported. Ectopic digit in the present case was differentiated from supernumerary digit because of late onset at the age of 24 years, ruccurence after surgery, unilateral appearance, had origin from central depression of a well defined, round plaque on the distal inter-phalangeal joint of left thumb and had curvature simulating cutaneous horn. X-ray thumb did not reveal any bone formation in this ectopic digit.

[ABSTRACT]  [FULL TEXT]     [PubMed]

Xeroderma pigmentosa is a rare autosomal recessive disorder with numerous oculocutaneous neoplasms, neurological abnormalities and extremely rarely associated with neoplasms of organs other than the skin and the eyes. Here we report two cases of xeroderma pigmentosa with numerous oculocutoneous malignancies in siblings born to a consanguinously married normal parents. One of these patients had a cystosarcoma phylloides in association with xeroderma pigmentoso, hetherto not reported in literature.

[ABSTRACT]  [FULL TEXT]     [PubMed]

A 26 -year-old male resident of Uttaranchal had a single large, erythematous, indurated verrucous plaque on chin of 1 year duration. He had suffered from visceral leishmaniasis 4 -years back for which he was treated with injection sodium antimony gluconate (SAG) IM OD for 20 days. He had never been to regions endemic for kola - czar (KA) or post - kola -azar-dermal leishmaniasis (PKDL). Skin biopsy showed chronic granulomatous inflammation in the dermis. Giemsa stain revealed LD bodies inside the macrophages. The patient was treated successfully with injection SAG 20 mg/kg parenterally for 60 days. To the best of our knowledge, this is probably the first case of PKDL from the hills of Uttaranchal.

[ABSTRACT]  [FULL TEXT]     [PubMed]

[FULL TEXT]     [PubMed]

[FULL TEXT]     [PubMed]

[FULL TEXT]     [PubMed]

Linear nail growth studies were carried out in 22 highlanders Ladakhi (3445m) and 6 lowlander male troops, in 4 during their fresh induction into high altitude (3445m) and in 2 during their stay in plains while on leave from high altitude. The average age of highlander Ladakhis was 21.82 years (range 16-36 years) and lowlanders was 34 years (range 29 - 40 years). There was significant decrease in nail growth in age matched (average age 34.25) highlander Ladakhis (93.11 /day, SD 7.24, P< 0.05) and in freshly inducted lowlanders (88.71/ day, SD 10.7µ, P<0.05) in contrast to average nail growth in plains (1191/day, SD 1.41) Although the average nail growth in highlander Ladakhis (99.34/day, SD 13.91) was more than the low landers inducted into high altitude (88.7s /day, SD 1 o.7µ) the difference was not found statistically significant (P> 0.05). However it does suggest some degree of acclimatization in highlanders. Hypoxic conditions and extreme cold conditions both appear to be factors responsible for decreased nail growth in high altitude areas.

[ABSTRACT]  [FULL TEXT]     [PubMed]