Fifty patients suffering from pityriasis versicolor were treated with either 2% ketoconazole cream (25 patients) or 1% terbinafine cream (25 patients). Diagnosis was confirmed by microscopic potassium hydroxide (KOH) examination and either of the cream was applied once daily for a duration of 2 weeks. Global assessment was done at the end of treatment with mycological and clinical cure rate of 88% and 96% in ketoconazole and terbinafine treated groups respectively. After a follow up of 3 months the relapse in ketoconazole group was 13.53% and 8.33% in terbinafine group with no side effects.

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Two cases of Brunsting Perry cicatricial pemphigoid are being reported for their rarity. Initially as a clearcut clinical diagnosis was not possible, both cases were labelled as a typical vesiculo-bullous disorder. Later only after repeated biopsies, dermoepidermal junction split, fibrosis and perivascular mononuclear infiltrate were seen and a diagnosis of cicatricial pemphigoid was established which was further confirmed by immunoflurescent studies. A favourable response to dapsone was observed in both cases.

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A 65-year old woman presented with long standing history of lupus erythematosus with episodic eruption of erythema mutiforme - like lesions. Immunological investigations revealed positive rheumatoid factor, ANF and histology was consistent with the clinical findings.

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A case of actinomycotic mycetoma presenting as multiple nodules with sinuses and swelling of left foot of six years duration is being reported. The diagnosis was confirmed histologically.

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A total of sixty patients with chronic urticaria (>3 months duration) were divided into three groups. Group A - was treated once daily with tab loratadine 10 mg. Group B- with cetrizine 10 mg and Group C - with tab fexofenadine hydrochloride 180 mg. Total duration of treatment was 4 weeks. Pre and Post treatment evaluation were made. It was observed that loratadine was superior to all, cetrizine was second and fexofenadine was third regarding over all clinical efficacy, while side effects like sedation was maximum observed in nine cases, with cetrizine, No side effects were observed with the other two regimens.

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Acquired cutaneous lymphangiectasia in two female patients with tuberculous lymphadenitis of the inguinal glands is described.

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A case of giant congential nevomelanocytic nevus with satellite lesions, vitiligo and lipoma is described, owing to the rarity of the association. The constellation of finding can be explained on the basis of a defect in the neural crest, which is considered to be a common origin of melanoblasts, Schwann cells, sensory ganglia, bone, fat, muscle and blood vessels.

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A 64-year old woman patient with dry pruritic rash, oral ulcers, persistent cough and significant weight loss was investigated and proved to be a case of hypereosinophilic syndrome.

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A case of Stevens - Johnson syndrome in a 48-year old woman not responding to conventional corticosteroid therapy which on subsequent investigations was found to be having chronic myeloid leukaemia. Patient improved with concomitant administration of busulphan therapy. Stevens - Johnson syndrome presentation in chronic myeloid leukaemia is rare.

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A 12-year old girl presented with asymptomatic multiple skin-colored grouped papules on the vulva. Histopathology revealed features of syringoma.

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A case of leukonychia totalis in a 20-year old. healthy man which manifested at the age of 2 years after an episode of acute illness is being reported.

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Keratosis follicularis spinulosa decalvans is one of a group of related disorders that shows keratosis pilaris with inflammation followed by atrophy. Here we report a case of this relatively rare disorder in a 6-year old boy who had associated psychomotor retardation.

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We describe two cases in which syringocystadenoma papilliferum was present in extremely unusual locations.

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Sixty randomly selected patients of acute guttate psoriasis were put on oral rifampicin for a period of 10-15 days. Improvement in reference to clearing of lesions was studied. Complete improvement was noticed in 26 patients and in 10 patients partial improvement was noticed while in 12 patients no improvement was seen. The rest of the patients did not report for follow up.

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Interface dermatitis is a histological reaction pattern which is seen in a number of conditions. One of the recent associations of the histology is in Acquired Immune Deficiency Syndrome. There are differentiating factors between interface dermatitis occurring in AIDS and those occurring in other conditions. These are discussed in detail.

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An 18-year olf boy presented with multiple bullae and atrophic depigmented lesions over the acral region. On examination he also had dystrophic and absent nails, discolored and dystrophic teeth and complaints of gradual decrease in hearing ability and dysphagia. No family history of similar lesions was present.

[ABSTRACT]  [FULL TEXT]     [PubMed]