A novel non-inflammatory type of pigmentation of the neck associated with nematode larvae on affected skin is described. The name 'Blue neck syndrome' is suggested for this condition because of the characteristic clinical appearance. Antinematode agents such as albendazole and neem oil have been found to be effective in the treatment.

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The aim of the trial was to study the efficacy and safety of the ointment containing mupirocin 2% and betamethasone dipropionate 0.05% in the treatment of infected dermatoses. Patients having either primary infection complicated by dermatoses or dermatoses infected secondarily were included in their study. From the analysis of 59 patients, it was noted that this ointment was found to be safe and very effective by dermatologist in the treatment of infected dermatoses in 94.9% of the patients. Similarly 89.8% of the patients reported more than 70% improvement in their symptoms after 7 days of treatment. No adverse effects were reported during the treatment period by any of the patients except worsening of skin lesions by one patient.

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Glucocorticosteroid therapy can occasionally lead to a serious and debilitating complication called osteone­crosis or avascular necrosis. While a prompt diagnosis of this complication can help in preventing significant morbid­ity in the affected patients, dermatologists in general, are often not conscious of this facet of steroid-related problems. The precise mechanisms responsible for this disease are not fully understood nor its prevalence in derma­tological practice. An attempt has been made in this article to review the current understanding of its pathogenesis, the risk factors associated with its occurrence and the methods for its early diagnosis and treatment. An attempt is also made to formulate a set of guidelines useful to a dermatologist for the prevention of this disabling complication.

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The clinico-histopathological features of 75 patients of lichen planus were studied. The male to female ratio was 1:13. The largest number of patients (30.6%) fell into the 31-40 year age group. Two patients had systemic hypertension. There was no history of lichen planus in the family. All patients presented with severe itching within 1-2 months of onset. Papular lesions were seen in 72% and papules with plaques were seen 16%. Lower limbs were involved in 38% of cases. Mucosal involvement was seen in 24% in addition to skin involvement ; nail involvement hypertrophicus (17.3%). Lichen planopilaris and oral lichen planus were uncommon. Clinico-histopathological discrepancies were observed in 7 patients. Civatte bodies were seen in only 37% of cases.

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The clinical efficacy and safety of once daily topical administration of 1% oxiconazole cream and lotion was assessed in an open label, non comparative trial in tinea cruris, tinea corporis and tinea pedis patients. In treated patients, severity scores of erythema, pruritus, scaling, vesicles, papules and burning showed a progressive fall over a period of 4 weeks at all the study centres. With lotion, mean percentage improvement of symptoms varied from 35% (week 1) to 87.6 - 98.7% (week 4). With cream, it varied from 35% (week 1) to 82.5 - 99.5% (week 4). Overall global evaluation response showed clear, excellent and good response in 60%, 21% and 17% of the patients treated with lotion respectively. With cream, excellent and good response was observed in 71%, 10% and 16% of the patients respectively. In T. pedis patients, clear, excellent and good response was observed in 4/8, 2/8 and 1/8 patients respectively with lotion. Cream showed clear (8/15), excellent (4/15) and good (1/15) in these patients. None of the patients out of 178 enrolled, reported any side effect during the trial.

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HIV infected individuals are susceptible to a wide variety of skin manifestations due to profound defect in cell-mediated immunity. We describe 2 patients with Disseminated Herpes Zoster, both the patients has associated HIV infection.

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Lincomycin is chemically distinct from all other available antibiotics except its semi-synthetic derivative clindamycin. Though it has been in the market for over three decades, there were not many clinical studies in India. This study has been undertaken to know its efficacy against Staphylococcus aureus, commonest organism of pyodermas in children. Material was taken from the lesions of 100 fresh cases of various types of pyodermas in children and studied by Gram stain and in 50% human blood agar and nutrient agar according to standard methods. The staphylococci thus isolated were tested for linocomycin susceptibility by using the disc diffusion technique. Lincomycin was given to all these children in a daily dose of 30 mg/kg 5 - 10 days. Treatment failure was defined as persistence of lesions after 10 days of treatment. 75% strains of staphylococci were susceptible to lincomycin in vitro and 95% of the patients responded to 5-10 days treatment. Five out of 100 children did not respond to treatment even after 10 days. No case of relapse was noticed among these 95 children for a period of 2 weeks. No side effects were observed and the drug was very well tolerated. Being highly effective and least toxic linomycin deserves a place in the antimicrobial arsenal of the modern dermatologists.

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Four young males with chronic non pitting swelling of lower legs associated with multiple ulcers, scars and pigmentation after parenteral drug abuse were observed in the Dermatovenereology department during last one year. Three of them had active ulcers which healed with withdrawal of offending drug, use of systemic and topical antibiotics and B-complex. All cases were referred to the deaddiction centre. The characteristic clinical features helped in the diagnosis even before history of drug abuse was obtained.

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Organoid nevi may rarely be complicated by development of keratoacanthoma. We report a 21-year old man who presented with a hyperkeratotic papule developing over a well demarcated hyperpigmented irregular plaque on the forehead. Histopathology revealed features suggestive of keratoacanthoma developing in a lesion of nevus sebaceous. Literature search revealed 11 such reported cases. Most of the reported patients were young and had lesions on the face. Such lesions should be excised completely to prevent any malignant change in the future.

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Two cases of folliculitis decalvans in a family are reported for its rarity and clinical interest.

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A male aged 35 years presented with large number of lesions on the face, neck, chest and back, since adolescence. Similar lesions were present in many other members of the family. The large number of lesions and the large pedigree of cases in the family made the case an interesting one to report.

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Porokeratosis affecting the mucous membrane of the tongue is reported in a young man.

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A case of Papillon-Lefevre syndrome (PLS) showed improvement of skin lesions after the loss of permanent teeth which is an unusual feature. The case is being reported because of this feature.

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