A total of 201 school children,belonging to a high altitude tribal area were examined for various dermatologic lesions including nevi. All the children were found to have one or more type of diseases/lesions. Pediculosis ea tis was the comtnonest disease (74.1%), followed by pityriasis simplex (33.3%), warts (20.4%), scabies (12.9%), pyoderma (8.5%) and papular urticaria (7.5%), Nevi were observed in 73.1% children. An acral erythfma associated with cold hands and feet was seen in 7.5% children.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]

[FULL TEXT]    [CITATIONS]

Clinical features of Multinodular Keratoacanthoma in two patients are reported. One patient was having squamous cell carcinoma of de novo origin with secondaries in lymph nodes in addition to multinodular keratoacanthoma.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]

[FULL TEXT]    [CITATIONS]

Twenty six patients with moderately severe acne were treated for 12 weeks with topical clindamycin hydrochloride 1% (12 patients) and the vehicle (14 patients). A good or excellent reduction was seen in the non-inflammatory acne lesion count in 3 (25%) of the patients on topical clindamycin and in none of the patients who used the vehicle (control).While 9 (75%) of the patients using topical clindamycin hydrochloride showed a good to excellent response in their inflammatory acne lesion count, only 2 (14.29%) of the control group showed a similar response. The response of the non-inflammatory acne to topical clindamycin hydrochloride 1% was comparable to that of the vehicle, (p >0.05) while the response of inflammatory acne lesions to topical clindamycin hydrochloride 1% was superior to that of the vehicle (p <0.05)

[ABSTRACT]  [FULL TEXT]    [CITATIONS]

A 45-year-old women presented with a large growth in the left groin. She was diagnosed as dermatofibrosarcoma protuberans histopathologically. Surgica resection of the tumour was done and the patient is under regular follow up to note recurrence. The huge size and the unusual location were the interesting features. The relevant differential diagnosis is discussed.

[ABSTRACT]  [FULL TEXT]   

An HIV positive patient with severe genital herpes and oral hairy leukoplakia is reported. Lower rate of heterosexual transmission and implications of transimission of HIV in a hospital set up are stressed.

[ABSTRACT]  [FULL TEXT]   

A case of a 35-year-old lady with scleromyxoedema is reported. The lesions were initially urticarial plaques and nodules. Which evolved into a generalized lichenoid papular eruption. Bone marrow was normal.

[ABSTRACT]  [FULL TEXT]   

Three young females with keratotic papular lesions on the chin are reported. No definite aetiological factor was identifiable. The co-existence of naevi in two 'suggests that if may probably be a developmental defect.

[ABSTRACT]  [FULL TEXT]   

A new animal model system was developed using dog's muzzle to demonstrate genetic transmission of depigmentation. Dog's muzzle is 'black in colour and heavily pigmented with pigement melanin. This study provides cluse to the genetic transmission of depigmentation. The genetic transmission of depigmentation of dog's muzzle was autosomal dominant.

[ABSTRACT]  [FULL TEXT]   

Transepidermal water loss (TEWL), high frequency electrical conductance (HFC) and the hydration state index (HSI) were measured in sldn lesions of 30 paucibacillary leprosy patients and compared with the contralateral uninvolved skin. While the TEWL, HFC and HSI all showed lower values in the lesion site, as compared to the contralateral skin sites, the differences between the two sets of values significant in HFC and. HSI only at 2% and 1% level respectively. A significant positive correlation (r = 0.69) was found to eidst between these two parameters. The parameters correlate well with the known reduced sweating in skin lesions of TT and BT leprosy and may therefore be considered as good objective parameters to confirm hypohydrosis in suspected skin lesions ofleprosy.

[ABSTRACT]  [FULL TEXT]   

A study was carried out to evaluate the drug resistance pattern and penicillinase production in skin isolated Staphylococcus aurpus. The disk diffusion method showed prevalence of: multidrug resistance among S. aureus, strains, isolated from locafised skin abscesses. method for detection of penicilfinase could detect this enzyme m 98.60/o of the isolates all fo which were resistant to penicillin and ampicillin. C16xacillin resistance as detected by the agar dilution method was found in 1.4% of the isolates. On the whole cloxacillin and gentamy'cin were found to be the most effective 'antistaphylococcal antibotics.

[ABSTRACT]  [FULL TEXT]   

Gugulipid is the standardized extract of the oleo-resin of Commiphora mukul (Burseraceace) an Indian medicinal plant. The active ingredients are two guggulsterones Z and E. Gugulipid is an effective hypolipidemic agent, has a marked antilipolytic activity in rats. Considering the pathogenesis of acne vulgaris and the pharmacological properties of Gugulipid this trial was initiated. Thirty patients with moderate to severe acne ( Grade 4) were included in this study. Tab Guglip was prescribed in tds dosage for 6 weeks. Excellent, good and moderate response was seen in nine (30%) fourteen (46.66%) and seven (23.33%) patients respectively out of the total thirty. No topical treatment was recommended except for local skin -hygiene. The drug showed excellent tolerance. Only three patients (10%) reported relapse when examined at 3 months follow up.

[ABSTRACT]  [FULL TEXT]