The patients who attended the STD clinic of our hospital during the last 10 years were studied retrospectively to work out the pattern of major sexually transmitted diseases viz. -syphilis, ionorrhoea, chancroid, lymphogranuloma vencreum and donovinosis. The total number of patients was 1093, The relative incidence of chancroid was found. higher (37.78%) than syphilis (32.47%), gonorrhoea (24 79%) mixed infections (3.38%), donovanosis (1.18%) and lymphogranuloma venereum (0.36%).

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Primary inoculation tuberculosis in two children confined to the face was seen over a period of six months the first case was an eleven year old boy with a painless non-healing ulcerative nodule over the left ala nasi with matted' non-tender submandibular lymphadenopath-y of 2 months duration. Mantoux test and biopsies of the lesion and the lymph node helped in the diagnosis. The second child was a six-year-old boy with a painless ulcerative lesion over the left cheek of 5 weeks duration. The left submandibular group of lymph nodes were enlarged, non-tender and matted. Aspiration cytology showed eptihelioid cells, lymphocytes, polymorphs and eosinophils. Mantoux test negative initially became positive by 2 months. The lesion started subsiding with antitubercular treatment in both the cases.

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In a family of four children, all females, three sisters presented with Clouston's disease or hidrotic ectodermal dysplasia. The case is reported for the rarity of presentation in a single generation with no history of other family members affected.

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A patient having contact dermatitis due to nickel on the wrist, sides of neck, thighs and legs, confirmed by patch tests with nickel sulphate, showed aggravation of the dermatitis following oral provocation with 25 mg nickel sulphate.

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A 7 year old girl had pseudo-ainhum, spina-bifida occulta, A hemivertebra and focal, neurogical deficit. The disease process was progressive for the last three years leading to amputation of the third digit and formation of constricting bands around -the fourth and the fifth digits of the left foot.

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A middle aged female with frequent attacks of non- inflammatory purpura was confirmed to have systemic lupus erythematosus. coagulation profile was-normal.

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A 45 year old female had grouped pruritic Papules and vesicles with a few scattered tensebullae, symetrically distributed on the extensor surfaces of limbs, back and buttocks. Nikolsky's sign' was negative. Histopathology revealed intra-epidermal suprabasal cleft along with acantholysis. Eosinophilic spongiosis was also present. The patient recovered with dapsone.

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A 17-year-old boy had bathing trunk nevus with multiple large neurofibromata on the nevus and raised intracranial tension presenting with bilateral papilloedema and pyramidal tract sings. This combination, of features is extremely rare.

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A 21 years old male had hereditary benign intra- epithelial dyskeratosis. His mother and younger brother also were found to have the same disease. All the three had oral and conjunctival lesions. The histopathological features were characteristic.

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Multiple lesions of psoriasis circumscribed to the hypopigmented patches of incontinetia pigmenti achromains were observed in a male child.

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Testicular functions in the form of testosterone, FSH and LH levels in serum by radio-immuno-assays, complete semen examination and a few testicular biopsies were studied in 30 men with leprosy (LL-7, BL-6, BB-1, BT-12 and 'fT-4). Serum testosterone levels were lowered in all the groups. Serum FSH and LH levels were elevated in lepromatous and borderline .1epromatous leprosy. Semen analysis showed oligospermia in LL and BL groups. Lepra bacilli in smars of semen were present in 2 LL case. Leprous changes were seen in the testicular biopsies.

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The faecal X normal healthy India have been determined by urea-triton solvent extraction method and its importance in the laboratory diagnosis of variegate porphyria has been discussed. The values ranged from:0.058 to 5.424 with a mean value of 1.64 + 1.32 microgram per gram dry weight of faeces. X porphyrin excretion was higher in males having non vegetarian diet. It increased with age and body weight. A statistically significant coefficient of correlation existed between all the three types of faecal porphyrins.

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Analysis of the clinical and laboratory data from 21 patents of cutaneous tuberculosis seen over a period of 10 years revealed that it is rare in eastern Libya. There were 15 males and 6 females. Lupus vulgaris was seen in 11, scrofuloderma in 4. Three patients each had tuberculosis verrucosa cutis and papulonecrotic tuberculid. The diagnosis in each case was confirmed histopathologically.

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