Forty-six patients suspected to have air borne contact dermatitis were tested with various plant antigens. Thirteen patients turned out to be sensitive to one or more antigens. The plant antigens, used for testing, were Parthenium hysterophorus, Lantana camara, Cynodon dactylon, Bougainvaled spectabills, calotropis procera, Argimone mexicana, Acacia arabica, Azadiracha indica, Eucalyptus rostrata, Saraka indica, triticum vulgare, Triticum aestivum, Dryopteris filix, Nerium indicum, Eclipta alba, Mangifera indica, Trianthema monogyna, Euphorbia hirta, Euphorbia thimifolia, Amaranthus spinosus, Amaranthus viridis, Carissa carands, Salvia plebia, Cyperus rotandus, Cassia occidentalis, Gynandropsis gynandra, Pennisetum typhoides, chenopodium album, Nicotana tobacum, Tagetes sp, Rosa indica, Cestrum nocturnum, Helianthus annus, Jasminum samlae, Thuja orientalis, Cajanus cajan, Hibiscus rosasinensis, Echinochloa cruss-galli, Phaseolus aureus, Ricinus communis and Alternantheria sessilis. The maximum positive reactions were elicited by Parthenium hysterophorus (30.0%) followed in the order of frequency by Amarnthus viridis (10.0%) Gynandropsis gynandra (10.0%) Pennisetum typhoides (10.0%), Nerium indicum (3.9%), Triticum vulgare (2.5%) and Dryopteris filix (2.5%). Rest of the plant antigens did not show any reaction. The male to female ratio was 5.5:1.

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A, rare episode of Seip-Lawrence syndrome manifesting in all three case siblings of consanpinous parents is reported. Two children we're male and one female. They exhibited low intelligence,' gaunt facies, depressed bridge of nose, large low-sct ears, thick lips and protruberant abdomen. Skin was showing hypermelanosis, hypertrichosis, absence of subcutaneous fat and acan nigrica*s with' very prominent perianal rUgO6itiS In addition, the first child was short statured having hypertrophic Clitoris, hepatomcoy, left ventricular hypertro hy, hyperglycaemia and glycossuria- without ketoacidosis. The second child was, having enlargement of penis, left ventricular hypertrophy,,hepatospienomegaly and abnormal GTT. The third and the youngest child was having only cutaneous changes and no viscoromegaly or biochemical abnormality. Nou Of these patients were having gigantism and advanced bone age.

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Chronic Scorbutic features as isolated deficiency were seen in an uneducated food faddist female. Unusual, sclerodermatous and discolored lesions on both legs we I re accompanied by typical perifollicular haemorrhages, follicular hyporkeratosis, corkscrew hairs, hypertrophic spongy bleeding gums and arthritis. Lesions were reversible on administration of 1000 mg ascorbic acid a day.

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A case of linear epidermal nevus with nevus comedonicus inovolving left side of the body and multiple cutaneous horns on nose, chin and eyelids is reported. Association of all the three disorders is rare.

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Two patients had classical clinico-pathological features of Sweet's syndrome. One of them had associated polycythaemia vera, myelofibrosis, mucosal lesions and haemorrhagic blisters. The patient showed a prompt response to corticosteroids. A long-term haematological follow up, is imperative in all patients.

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A team conducted a VDRL sero-survey in Sirmur district of Himachal Pradesh during September 1981. Of 698 persons examined 4.6% were reactive, by the qualitative test. By the quantitative test, the" overall reactivity at a dilution of four and above was 1.1% and at a dilution of eight and above, it was Q.6%. All age groups of twenty years and above were reactive. No reactivity was observed amongst the teenagers, Reactivity amongst males and females was 3.9%, and 5.4% respectively.

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Intralesional triamcinolone and oral predtiisolone in low dosage with topical fl6ocinolone acetonide were tried in 10 cases of torokeratosis of mibehi. Moderate to good response was observed in 60% cases with flattening of the lesions, to, complete disappearance.

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Contact dermatitis of the hands was studied in 70 patients showing exclusive involvement of the hands. They were patch tested with various antigens. Forty one patients showed positive patch tests to one or more antigens. Females showed a higher rate of positivity than males. Female to male ratio was 2. 72. Vegetables (68.8%) were the most common sensitizer followed by soaps and medicaments.

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Fourteen patients, 9 males and 5 females with chronic severe intractable psoriasis resistant to conventional therapies were treated with methotrexate. Five had psoriatic erythroderma while 9 had extensive disease. Methotrexate therapy given orally in weekly single doses of 20-30 mg was effective in all cases. The side effects observed included nausea and vomiting headache, pain abdomen, diffuse alopecia and loss of appetite.

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Three cases of primary dapsone resistance in paucibacillary leprosy are reported from Trivendrum. All these 3 cases of indeterminate leprosy deteriorated on supervised daps one monotherapy but responded well to combined treatment with rifampicin and clofazimine.

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A 38 year old male developed acquired digital fibrokeratomas on the right hand associated with Dupuytren's contracture on the left hand. The possible relationship between these two fibrodysplastic conditions is considered.

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All the 138 school children whose parent (s) had leprosy were examined for leprosy or other dermatological disease. BT leprosy was detected in one child, while in 2 other cases, the diagnosis of leprosy was doubtful. Among the other dermatological diseases. the prevalence of pityriasis versicolor and pediculosis capitis was high.

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An analysis of 50 patients having cutaneous metastasis arising from various malignancies revealed that the primary tumours in men were carcinomas of the lung (14%), oesophagus (8%) stomach (6%) and melanoma (6%). The most common primary tumours in women, were carcinomas of the breast (20%) ovary 18%) lung (6%), and (4%) The cutaneous

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