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1981| January-February | Volume 47 | Issue 1
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CLINICAL AND LABORATORY INVESTIGATIONS
Contact Hypersensitivity to Local Antibacterial Agents
JS Pasricha, Bharati Guru
January-February 1981, 47(1):27-30
PMID
:28211390
To find out the incidence of contact hypersensitivity due to various antibacterial agents, patch tests were performed with these medications in 101 patients suspected to havek developed contact dermatitis due to some such agent. Positive patch tests were obtained with nitrofurazone, (furacin) in 56 cases, neomycin in 28 cases penicillin in 12 cases, tyrothricin (tyroderm), gentamicin (genticyn), framycitin (soframycin) and oxytetracycline (terramycin) in 13 cases each, triple sulfa , and mercurochrome in 9 cases each and acriflavine in 4 cases. Two cases showed patch tests with brilliant green, but none with gentian violet. Twenty eight patients were negative with all drugs tested. Many patients showed positive patch tests with more than one antibacterial agent.Neomycin 20% in petrolatum gave more frequent positive patch tests compared to the commericial 0.35% neomycin ointment or 20% aqueous neomycin, but there was no significant difference between the commercial 0.2% nitrofurazone ointment, 2% nitrofurazone in petrolatum of 22 controls, 6 patients showed positive patch tests with the commercial neomycin ointment as well as 20% neomycin in petrolatum, 1 patient with 0.2% nitrofurazone ointment and 5 patients with 200% nitrofurzone in petrolatum .
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Evaluation of 8-methoxypsoralen and Solar Ultraviolet Light (puvasol) in Psoriasis
PG Talwalkar, RB Gadgil, C Obemi, VD Parekh
January-February 1981, 47(1):17-20
PMID
:28211387
Thirty three patients suffering from psoriasis took part in PUVASOL treatment study. All the patients were exposed to sunrays 4 times a week between 11-30 a.m. and 1-30 p.m. two hours after ingesting 8-MOP. The initial exposure was for 15 minutes. Exposure time was gradually increased upto a maximum of 90 minutes. 17 out of 27 patients had grade 3-4 'unprovement, 8 patients had grade 1-2 improvement, while 2 patients did not show any improvement. The results obtained were corn arable to thos
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Clinical Evaluation of Clofazimine in Vitiligo
KC Shah
January-February 1981, 47(1):40-41
PMID
:28211394
In a purely clinical unbiased study, fifty patients' with multifocal extensive, vitiligo were given oral clofazimine therapy for six months and another fifty patients were kept as controls. All the patients were exposed to sunrays for thirty minutes daily. Significantly more patients in the treated group developed pigmentation of the patches compared to the, control group. But,the pigment dis appeared soon after stopping the treatment. It may be tried in extensive multifocal vitiligo cases only where known therapeutic agents are not effective.
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Study of ABO Blood Groups in Vitiligo
TR Kapur, HS Narula, MN Mohan, MS Misra
January-February 1981, 47(1):38-39
PMID
:28211393
ABO blood groups were determined in 110 cases of vitiligo and an equal number of controls among Indian Armed Forces personnel and their dependents. Statistically there was no significant difference.
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Dermatoglyphics in Ichthyosis and Alopecia Areata
KC Verma, VK Jain, RK Joshi
January-February 1981, 47(1):35-37
PMID
:28211392
A total of 80 cases comprising of 40 controls and twenty each of ichthyosis and alopecia areata were studied for dermatoglyphic patterns and ridge count. Statistically significant increased incidence of whorl pattern was observed in female cases of autosomal dominant and sex linked ichthyosis. Significant change in the distribution of patterns was found in female cases of alopecia areata. -
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Treatment of Psoriasis: Comparison of 8-methoxysoralen and 4,5,8- Trimethylpsoralen Using Sunlight (low Dosage Daily Regime)
NV Sehgal, S Parikh
January-February 1981, 47(1):6-8
PMID
:28211385
A comparative study of the effectiveness of 8-methoxypsoralen and 4,5,8-trimethylpsoralen 'm the treatment of psoriasis revealed that when taken orally in 20 and 10 mg. doses respectively, and 2 hours later lesions exposed to natural sunlight, remission was achieved within 8 weeks. Progressive improvement among patients was variable. Effectiveness of both drugs was comparable, and the difference was insignificant. Drug 4,5,8 trimethylpsoralen achieved equal remission at half the dosage, and for this reason its use is advocated. Failure of the drugs in 2 patients and recurrence in 1, points out the limitations of this method of treatment.
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A Spectrophotometric Study of Porphyrins in Patients with Psoriasis with Special Reference to Photosensitivity
Inderjeet Kaur, F Handa, KS Sidhu
January-February 1981, 47(1):31-34
PMID
:28211391
Quantitative Porphyrins in blood urine and stools of 30 patients with psoriasis had been' compared with that of 10 normal controls. Porphyrin levels have also been compared in psoriitic patients with and without history o I f photosensitivity, The erythrocyte coproporphyrin levels in patients, with photosensitivity were higher than that in patients without photosensitivity, and, this rise, was statistically significant. However, psoriasis per se does not. seem to affect porphyrin levels.
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Delayed Hypersensitivity in Psoriasis
Bhushan Kumar, Surrinder Kaur, Mahendra Kumar
January-February 1981, 47(1):21-23
PMID
:28211388
Twenty two adult male patients of psoriasis and 100 normal Volunteers Were skin-tested ' with DNC-B, mumps skin antigen, candidin coccidiodin, PPD, croton Oil and histamine hate Except for 'decreased mine phosphate sensitization seen: with DNCB, the response of psoriabics to, skin testing was comparable with the normals.
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Photochemotherapy For Psoriasis with Psoralen and Sunlight
FV SadanandaNaik, PP Paily, KG GopinathaPillai, PU Asokan
January-February 1981, 47(1):9-16
PMID
:28211386
A double blind study with systemic psoralen and sunlight exposure therapy in psoralen and is reported. Evaluation was done on the basis of clinical features, patients subjective improvement, severity of scores and histopathology. 66.7% of patients on systemic psoralen and sunlight responded with complete clearance of lesions in 21 to 56 days and 33.3% of patients showed moderate improvement. This study shows that systemic psoralen and direct sunlight elwsure is a safe and effective line of t reatment for psoriasis. We feel, this method of treatment can be recomended as a routine in psoriatic patients in our country.
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Neuropathology of Psoriasis
NL Sharma, B lyengar, Sardari Lal
January-February 1981, 47(1):24-26
PMID
:28211389
The histopathology of nervous, tissue, elements was studied with three different stains in the lesions and the uninvolved skin of psoriasis vulgaris patient. No abnormal change, was detected.
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Role of school survey in the control of leprosy
Sushi Chandra, Gurmohan Singh, Paramjit Kaur
January-February 1981, 47(1):42-44
PMID
:28211395
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ARTICLES
Self-assessment programme
January-February 1981, 47(1):56-58
PMID
:28211399
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CASE REPORTS
Linear morphoea with hypertrichosis and entrapment neuropathy
K Pavithran
January-February 1981, 47(1):45-49
PMID
:28211396
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ARTICLES
Association News and Notes
January-February 1981, 47(1):66-68
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CASE REPORTS
Mudi chood in a male
KG Gopinatha Pillai, PP Paily, P.V.S Naik
January-February 1981, 47(1):50-52
PMID
:28211397
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ARTICLES
Announcements
January-February 1981, 47(1):64-65
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What is your diagnosis ?
January-February 1981, 47(1):59-60
PMID
:28211400
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Short communications
January-February 1981, 47(1):61-62
PMID
:28211401
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CASE REPORTS
Temporal arteritis following trimethoxy psoralen therapy
A Mahakrishnan, GV Shesan Narayanan
January-February 1981, 47(1):53-55
PMID
:28211398
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PRESIDENTIAL ADDRESS
Presidential address
SR Sadana
January-February 1981, 47(1):1-5
PMID
:28211384
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ARTICLES
Abstracts
January-February 1981, 47(1):63-64
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