Skin blanching and clinical efficacy of a liposomally entrapped Triamcinolone acetonide (TRMA) cream was compared with that of the conventional TRMA cream in healthy human volunteers and eczema patients respectively. Both the creams showed equal efficacy in eczema patients. A significant reduction in the skin blanching response with the liposomal TRMA cream as compared to the conventional TRMA cream suggests a decrease in the systemic absorption of the corticosteroid with the former.

Female population comprised of 544 with vaginitis and 258 asymptomatic were screened for presence of Bacterial Vaginosis (BV), Trichomonas vaginalis, Candida albicans, Gardnerella vaginalis and Mycoplasma hominis. Bacterial vaginosis, diagnosed on the basis of clinical criteria and gram's stained vaginal smear findings, was present in 50 percent of symptomatic cases and 21.8 percent of asymptomatic women. G. vaginalis, M. hominis and T. vaginalis were significantly associated with a diagnosis of BV. BV showed a positive correlation with lower socio-economic status and parity of more than 2. Prevalence of G. vaginalis was significantly higher among women who were ? 33 years of age, had been married for a shorter duration, gave history of intercourse in the preceding 48 hours and were of lower socio-economic status.

Gradual diminition of cutaneous insensible perspiration is observed with advancement of age which becomes significant suggesting altered stratum corneum, in old age.

Serum proteins, zinc, copper, acid phosphatase (AcPase) and alkaline phosphatase (AlPase) were studied in both active and remission phases of psoriasis. Data were compared with healthy controls, ?1, ? and ? globulins were high in active phase while ?1 and ? globulins were at par in remission phase. Serum copper was low but zinc and alkaline phosphatase were significantly high in both active and remission phases of the disease. Acid phosphatase level was at par in all the experimental groups. Study suggests a positive correlation of globulin, zinc and Alpase in active and remission phase of psoriasis.

Thirty cases (group I) having psoriasis were studied with a view to assess the efficacy of combination of short contact coal tar therapy, sunrays exposure and short contact anthralin therapy. Results were compared with thirty patients (group II) with psoriasis using anthralin paste as per Ingram technique as control. The combined short contact therapy in group I patients with intensive 90 to 120 minutes treatment sessions done once in every alternate day resulted in complete clearing in 19 (63.3%) patients, 3 (10%) showed more than 50% clearing of lesions, 6 (20%) had 21-50% improvement of lesions, one (3.3%) had 5-20% improvement and disease got worse in one (3.3%) case. The average rate of clearance of lesions started to appear between 10-22 days with a mean of 16 days. In group II out of 30 patients using anthralin paste every day, 16 (53.3%) showed complete clearing of lesions, 5 (16.6%) showed more than 50% clearing of lesions, 4 (13.3%) had 21-50% improvement of lesions, two (6.6%) patients had 5-20% improvement of lesions and the disease got worse in 3 (10%) cases. The average rate of clearance of lesions started to appear between 18-28 days with a mean of 23 days. The combined short contact therapy schedule allows minimal time away from work, decreased hours per week in contact with coal tar and anthralin, decreased cost and a low risk of side effects.

A total 18 patients of stationary acrofacial vitiligo, relatively resistant to medical treatment, of various age were selected for blister grafting. Duration of their disease varied from 3 to 10 years. The autografts were taken up and cosmetically acceptable result were seen in approximately 90% of the cases during the follow up period varying from 6 months to 2 years.

The incidence of Chlamydial infection was studied in 160 women of different age groups in Hyderabad from different categories of patients. They were 50 prostitutes from red light area, 40 women with mucopurulent vaginal discharge, 40 women with infertility and 30 women attending antenatal clinics. The enzyme linked immunoassy incorporated in Orgenics Immunocomb kit (supplied by Orgenics Ltd. Israel) was used to detect low level of antibodies in single serum dilutions. The study showed an incidence of 54% in prostitutes, 47.5% in women with mucopurulent vaginal discharge, 15% in women with infertility and 13.35% in women attending antenatel clinics.

Two cases of cicatricial pemphigoid are reported. In one patient (case 1) the disease started as early as at 27 years of age. In both the cases oral mucosa was first affected and circulating anti BMZ antibodies were negative.

A case of primary systemic amyloidosis with periorbital pigmentation is reported. She had muscular weakness, weight loss, paresthesia of hand, hoarseness, oedema, dyspnoea, macroglossia, dysphagia & purpura. There was extreme fragility of both involved or non-involved skin. Fat aspirate from abdominal subcutaneous tissue was positive for amyloid.

A case of segmental Tuberculosis Verrucosa Cutis is reported in 10 year old boy. The condition was resembling the ascending lymphangitic type of sporotrichosis. The lesions cleared on treatment with INH 150 mg daily for 6 months.

A case of cysticercus cellulosae is reported with its unique histopathological features.

A 45 year old male presented with a large yellowish irregular surfaced tumour of 5 years duration, situated over lower back. There were comedo like lesions over it and a few nodules on top showed necrosis. A diagnosis of naevus lipomatosus superficialis was made. Histopathology revealed presence of mature adipose tissue interposed with bundles of collagen within the reticular dermis. Late appearance, large size, extension beyond midline, comedolike lesions were some unusual features observed in this rare disorder.

Tuebrculoid leprosy involving the hairy scalp is described. The lesion was single, raised, involved the hairy area of scalp and extended to the surrounding non hairy area also. It is interesting to note that scalp, which is presumed to be immune to leprosy, was singled out by the Mycobacterium leprae, leaving other cooler areas free. To the best of our knowledge such a preferential scalp affliction has not been reported earlier in literature.

A case of Pachyonychia congenita is being reported. The interesting feature being the onset of nail changes beyond the first few years of life.

A case of ALHE presenting as multiple, linearly arranged polypoidal nodules in left infrascapular region in a 48 years old male is presented.

Two cases of Faun-tail naevus are presented. Both the patients had clinical and radiological evidence of bifid 5th lumber spine. However, neither of them had any neurological complications.

A case of photosensitive dermatitis, occurring after the second application of 2.5% selenium sulphide (Selsun shampoo, Abbot), is reported. The shampoo was diluted to half strength with water, before use. The patient had pityriasis versicolor, with extensive lesions on the covered as well as exposed areas.

A case of periumbilical perforating pseudoxanthoma elasticum occurring characteristically in an elderly, multiparous, obese, diabetic female is reported.

A case of generalized acute mucocutaneous herpes simplex is reported in a 15 years old boy. There was neither underlying disease nor any evidence of genetic or acquired immune deficiency.