A rare case of chronic tophaceous gout, in a 27 year old female on diuretics for chronic congestive cardiac failure with characteristic histopathological and radiological changes is reported.

28 adult patients of pityriasis versicolor were treated with either oral ketoconazole (13 patients) or topical ketoconazole (15 patients). Though mycological response was equal in both the regimes, good clinical response was seen in 69.23% of patients on oral ketoconazole while 73.33% of patients on topical ketoconazole, with least side effects seen with topical ketoconazole. Therefore topical ketoconazole appears to be better than oral ketoconazole in the treatment of pityriasis versicolor.

Several cases of bindi-induced depigmentation have been presented in the past but the mechanisms underlying para-tertiary-butyl-phenol induced depigmentation remain unclear. A case is presented here in order to emphasize the current support on immune mediated mechanisms leading to damage to the melanocytes.

Six cases of familial acro-osteolysis in 15 members of 3 generations of a family are reported. Their pedigrees traced followed an autosomal dominant pattern. Five of these patients were wrongly labeled as patients of leprosy and treated with dapsone monotherapy for variable periods without any benefit. Awareness and differentiation of acro-osteolysis from leprosy is emphasized.

15 cases of subcorneal pustular dermatosis (SPD) were observed during June to October 1992. 5 were fresh cases and 10 were old patients with relapses. Seasonal variation with relapses only during successive summer months was observed. Histopathology revealed typical subcorneal pustules filled with neutrophils in 10/15 cases. All patients responded satisfactorily to 150 mg dapsone daily therapy.

A male patient of secondary syphilis presented with nodular and ulcerative lesions. He did not respond to standard treatment of syphilis with benzathine pencillin, due to associated HIV infection which was subsequently detected.

Two female patients with congenital naevus spilus are reported. The diagnosis was confirmed by clinical features and histopathology.

Twenty seven year old sepoy presented with vitiligo lesions distributed along the areas predominantly involved in air borne contact dermatitis.

A case of porokeratosis of Mibelli with a zosteriform distribution in an adult male is described. His daughter too had lesions on her face. Histopathology showed the characteristic cornoid lamella.

An 18 year female with disseminated superficial actinic porokeratosis is reported. Response to topical tretinoin was good.

Pincer nail deformity affecting the toe nails in a boy was seen with similar involvement of nails traceable in two previous generations. The probable aetiology is discussed.

Hereditary camptodactyly can be associated with several other developmental anomalies. A case of hereditary camptodactyly in a 14-year-old girl with associated palmoplantar hyperhidrosis is reported.

A case of borderline tuberculoid Haneen's disease on MDT developing hyper pyrexia and other malaria - like features, till now undescribed is reported.

An 8-year-old boy presented with multiple recurrent painful ulcers mainly over legs for the last 2 years. A diagnosis of TB cutis was made and he was put on anti tubercular therapy for last 1 year without any signs of improvement. This lead us to suspect the diagnosis pyoderma gangrenosum.

A 14-year-old boy with haemorrhagic crusting of lips and congestion of eyes of a month's duration progressed to Stevens Johnson syndrome. A retro-peritoneal lymphoma was detected after extensive investigation. Stevens Johnson syndrome when persistent and atypical in presentation needs investigation for underlying malignancy.

A case of acute haemolytic crisis following dapsone treatment in a patient of Hansen's disease is reported.

Erythema multiforme following application of minoxidil solution for the treatment of androgenetic alopecia is reported in a male. Recurrence of the eruption following reapplication of minoxidil solution as well as after oral administration of minoxidil tablets confirmed the aetiology. Patch test with minoxidil was negative.