The role of gastrointestinal parasites as aetiological factor in chronic urticaria was evaluated in 300 patients. Fifty nine (19.66%) patients were detected to have intestinal parasites compared to 18% among the control group. The difference was statistically insignificant. No significant improvement was noted with specific treatment of helminthic infestation.

Thirty patients of oriental sore had received ketoconazole as treatment. The dose was 400 mg/day in divided doses. The duration of treatment ranged from 14 to 40 days with the mean of 31.6 days. Twenty eight patients (93.33%) had shown complete healing. Two patients (6.66%) did not show response. Ulcerative variety had complete response in all cases, whereas nodular variety had the same in 10 (83.33%) cases.

Computer tomographic features of the brain in 2 cases of neurosyphilis are described. Less prominence of the cortical sulci suggesting cortical atrophy was the predominant feature in a case of general paralysis of insane. Diffuse, irregular, non-enhancing, low-attenuated area in the cortical and subcortical region of the right temporoparietal lobe of a patient with vascular syphilis, suggested infarction of the brain.

A 21-year old man presented with multiple noduloulcerative lesions in a linear form resembling sporotrichosis. Histopathology showed the fungal bodies suggestive of chromoblastomycosis and the patient responded to potassium iodide therapy.

A woman with pemphigoid had massive eosinophilia (51% eosinophils in differential count and total eosinophil count 8850/106/L). She responded to oral predinisolone. After 2 months of starting the treatment the differential count showed 15% eosinophils and total eosinophil count fell to 950/106/L. This case supports the hypothesis that imflammatory cells like eosinophils have an important role in the pathogenesis of pemphigoid.

The classical pityriasis rosea presents with erythematous papulosquamous lesions but it has got many morphological variants. The unilateral pityriasis rosea is a very rare variant of PR. We are reporting a case of unilateral pityriasis rosea.

A 30-year-old woman had porokeratosis palmaris et plantaris disseminata with unusual features. These included the sex of the patient, absence of family history of similar disease, onset of lesions on the shins and a significant furrow. There was also associated diabetes mellitus. It is suggested that porokeratosis palmaris et plantaris disseminata falls in the middle of the spectrum of porokeratoses.

A 1½ year old male child presented with a nodular and a plaque lesion with history of urtication and bulla formation off and on. Darier's sign was positive. Biopsy confirmed the diagnosis of mastocytoma.

A 20-year old man was referred to our department with universal nerve thickening and beading for the exclusion of Hansen's disease. On examination he had multiple soft mollusca fibrosa lesions, café-au-lait macules over the face and trunk along with Lisch nodules in both the eyes. There was no neurological deficit. Slit skin smear for acid fast bacilli was negative. Sural nerve biopsy showed neurofibroma lesions.

A case of atrophoderma of Pasini-Pierini is described and its classical clinical and pathological features highlighted. Its distinguishing features from morphoea and other atrophic dermatoses are discussed.

A case of cowpox of vulva in a 19 year old rural girl was diagnosed clinically because of history of contact with cows and other animals, fever, typical umbilicated, circular, yellow, 2 to 10 mm pustules with associated oedema, erythema and lymphadenopathy. Diagnosis was confirmed histopathologically as there was marked spongiosis, reticular-degeneration and occasional intracytoplasmic inclusion body. She developed toxic erythema on 12th day of illness and was cured in 22 days.

Acquired hypertirichosis lanuginose developed rapidly in a patient with no detectable malignancy. Soft, fine, downy hair growth was noticed on the face, ears, limbs and trunk. Bilaterally symmetrical vitiliginous macules were present on the ear and preauricular region. This case is reported because of its rarity, absence of any detectable malignancy and development of vitiligo, which to our knowledge has not been reported earlier.

A case of blastomycosis like pyoderma developing over burn sites on the extremities of a 19-year old male Libyan is reported. The patient did not have any underlying medical problem.

Two cases of subcutaneous granuloma annulare are reported. Clinical presentation was in the form of hard subcutaneous nodules, histopathology confirmed the clinical diagnosis. The cases were unique because of onset in adult age, occurrence over unusual sites and absence of classical lesions of granuloma annulare elsewhere.

A case of Waardenburg's syndrome with typical clinical features and unusual developmental anomalies of thoracic cage and upper extrmitites is presented.

An infant presenting with extensive aplasia cutis on lower extremities later developed blisters on skin and mucous membrane. Clinical features and histopathological examination of skin favoured the diagnosis of Bart syndrome.