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Year : 2012  |  Volume : 78  |  Issue : 1  |  Page : 89--92

Primary extramammary Paget's disease with extensive skeletal metastases

1 Department of Dermatology, Apollo Hospitals, Hyderabad, India
2 Department of Pathology, Apollo Hospitals, Hyderabad, India
3 Department of Dermatology, Image Hospital, Hyderabad, Andhra Pradesh, India

Correspondence Address:
Indukooru Subrayalu Reddy
A-8, Anand Sheel Enclave, Nandi Nagar, Road No. 14, Banjara Hills, Hyderabad - 500 034, Andhra Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0378-6323.90954

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Extramammary Paget's disease (EMPD) is an uncommon malignancy that is most commonly seen in the vulval area in postmenopausal women. Pruritus is the predominant symptom. The clinical presentation can be so nonspecific that it can be misdiagnosed as an inflammatory or infective condition. We report an elderly male patient with EMPD over the pubic area, which remained asymptomatic for 5 years; he presented with severe low backache of 5 months' duration. Skin biopsy and immunohistochemistry showed the typical epidermal changes and deep dermal invasion. Positron emission tomography scan revealed involvement of regional lymph nodes as well as extensive skeletal metastases.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow