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Year : 2010  |  Volume : 76  |  Issue : 2  |  Page : 213-214

Leonine facies in an old man

Department of Skin and VD, MGIMS, Sevagram, Maharashtra, India

Date of Web Publication10-Mar-2010

Correspondence Address:
Atul Dongre
Department of Skin and VD, MGIMS, Sevagram, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0378-6323.60549

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How to cite this article:
Dongre A, Gondse S, Kar S. Leonine facies in an old man. Indian J Dermatol Venereol Leprol 2010;76:213-4

How to cite this URL:
Dongre A, Gondse S, Kar S. Leonine facies in an old man. Indian J Dermatol Venereol Leprol [serial online] 2010 [cited 2020 Oct 25];76:213-4. Available from:

A 68-year-old male farmer presented with multiple asymptomatic lesions over the face since childhood. These lesions gradually increased in size and number over a period of six decades to attend present size and shape. There was no history of bleeding from the lesions. On further probing, he mentioned similar kind of lesions involving face of his younger brother.

Examination revealed multiple, firm, skin colored, and few hyperpigmentd papules and nodules over the forehead, glabella, and nose alongwith obliteration of nasolabial fold [Figure 1].

A punch biopsy from one of the nodule over forehead was taken. Histopathological features of hematoxylin and eosin-stained section are shown in [Figure 2],[Figure 3],[Figure 4].

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2.Lee KH, Kim JE, Cho BK, Kim YC, Park CJ. Malignant transformation of multiple familial trichoepithelioma: Case report and literature review. Acta Dermatol Venereol 2008;88:43-6.  Back to cited text no. 2      
3.Salhi A, Bornholdt D, Oeffner F, Malik S, Heid E, Happle R, et al. Multiple familial trichoepithelioma caused by mutations in the cylindromatosis tumor suppressor gene. Cancer Res 2004;64:5113-7.  Back to cited text no. 3  [PUBMED]    
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6.Biggs PJ, Wooster R, Ford D, Chapman P, Mangion J, Quirk Y, et al. Familial cylindromatosis gene localised to chromosome 16q12-q13: Evidence for its role as a tumour suppressor gene. Nat Gene 1995;11:441-3.  Back to cited text no. 6      
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  [Figure 1], [Figure 2], [Figure 3], [Figure 4]


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