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Year : 2008  |  Volume : 74  |  Issue : 3  |  Page : 248--250

Suspected cardiac toxicity to intravenous immunoglobulin used for treatment of scleromyxedema

1 Department of Dermatology and Venereology, Medical College, Thrissur; Medical College, Calicut, India
2 Assistant surgeon, General Hospital, Thalassery, India

Correspondence Address:
M P Binitha
"Haritha", P.O. Beypore North, Calicut - 673 015
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0378-6323.41372

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Scleromyxedema is a rare, generalized form of lichen myxedematosus, which may be associated with systemic involvement and can be fatal. The therapeutic options available provide partial or inconsistent response and are associated with significant adverse effects. We report a case of scleromyxedema with cardiac involvement, treated with low-dose intravenous immunoglobulin, with almost complete clearing of the skin lesions. The patient died after three cycles of treatment, possibly due to myocardial infarction.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow