Indexed with PubMed and Science Citation Index (E) 
Users online: 3187 
     Home | Feedback | Login 
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
  Navigate here 
   Next article
   Previous article 
   Table of Contents
 Resource links
   Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
   Article in PDF (455 KB)
   Citation Manager
   Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
* Registration required (free)  

  In this article

 Article Access Statistics
    PDF Downloaded141    
    Comments [Add]    
    Cited by others 1    

Recommend this journal

Year : 2004  |  Volume : 70  |  Issue : 3  |  Page : 186

Silver sulphadiazine for MRSA infections

Consultant Dermatologist, Mallya Hospital, Bangalore, India

Correspondence Address:
11 Plain Street, Shivajinagar, Bangalore - 560001, India
[email protected]

How to cite this article:
Tehrani R. Silver sulphadiazine for MRSA infections. Indian J Dermatol Venereol Leprol 2004;70:186

How to cite this URL:
Tehrani R. Silver sulphadiazine for MRSA infections. Indian J Dermatol Venereol Leprol [serial online] 2004 [cited 2021 Jan 24];70:186. Available from:

In response to the article on methisillin resistant Stophylococcus (MRSA),[1] no account will be complete without a mention of a medication which has been in use for the last 30 years, and which has saved more lives than all the other topical preparations put together - silver sulphadiazine cream. Although primarily used in burns, it has been used in herpes zoster and in toxic epidermolysis. It is useful in multi-drug resistant bacteria along the entire spectrum, from MRSA to Pseudomonas aerogenesa.[2]

As compared to mupirocin, silver sulphadiazine cream has the following advantages:
1. It is very inexpensive.
2. While mupirocin comes in a 10 gram tube, silver sulphadiazine is also available in a 1 kilogram jar.
3. Mupirocin is available in a greasy ointment base while silver sulphadiazine comes in a water washable base.
4. Silver sulphadiazine is used both for treatment and prevention.

A combination of silver sulphadiazine and chlorhexidine, available in several brand names in India is more potent than silver sulphadiazine alone.[3]

   References Top

1.Sachdev D, Amladi S, Natraj G, Baveja S, Kharkar V, Mahajan S, et al. An outbreak of methicillin-resistant Staphylococcus aureus (MRSA) infection in dermatology indoor patients. Indian J Dermatol Venereol Leprol 2003;69:377-80.  Back to cited text no. 1    
2.Wright JB, Lam K, Burrel RE Wound management in an era of increasing antibiotic resistance-a role for topical silver treatment. Am J Infec Control 1998;26:572-7.  Back to cited text no. 2    
3.Fraser JF, Bodman J, Sturgess R, Faoagali J, Kimble RM. An vitro study of the antimicrobial efficacy of a1% silver sulphadiazine and a 0.2% chlorhexidine cream and a silver coated dressing. Burns 2004;30:35-41.  Back to cited text no. 3  [PUBMED]  [FULLTEXT]


Print this article  Email this article
Previous article Next article


Online since 15th March '04
Published by Wolters Kluwer - Medknow