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Year : 2004  |  Volume : 70  |  Issue : 3  |  Page : 156--158

Inducing repigmentation by regrafting and phototherapy (311 nm) in punch grafting failure cases of lip vitiligo: A pilot study

Pigmentary Disorder Unit, Rita Skin Foundation, GD-381, Sector III, Salt Lake, Kolkata - 700 106, India

Correspondence Address:
Koushik Lahiri
Pigmentary Disorder Unit, Rita Skin Foundation, GD-381, Sector III, Salt Lake, Kolkata - 700 106
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Source of Support: None, Conflict of Interest: None

PMID: 17642595

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BACKGROUND: Punch grafting followed by PUVA/PUVASOL is an established mode of therapy in vitiligo including that on the lips. AIMS: To assess the efficacy of NB-UVB along with regrafting in patients in whom punch grafting had failed to evoke any response. METHODS: Five patients with stable and isolated lip vitiligo in whom punch grafting and PUVA had failed to produce pigmentation were treated by regrafting and subsequent NB-UVB (311 nm) phototherapy. RESULTS: Complete repigmentation was observed in three of the five cases after 16 weeks. In the remaining two, the results were mixed. CONCLUSIONS: Stable lip vitiligo usually responds very well to punch grafting and PUVA/PUVASOL. In patients who fail to respond to this treatment, complete repigmentation following regrafting and NB-UVB is an observation that needs to be explained.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow