Indexed with PubMed and Science Citation Index (E) 
Users online: 463 
     Home | Feedback | Login 
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
    Next article
    Previous article
    Table of Contents

    Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded375    
    Comments [Add]    
    Cited by others 3    

Recommend this journal


Year : 2004  |  Volume : 70  |  Issue : 1  |  Page : 25--28

Multicenter, open-label, non-comparative study of a combination of polytar and zinc pyrithione shampoo in the management of dandruff

1 Department of Skin & STD, Grant Medical College, Mumbai, India
2 Consultant Pharmacologist, Mumbai, India

Correspondence Address:
Shailendra N Sawleshwarkar
Department of Skin & STD, Grant Medical College, Byculla, Mumbai - 400008
Login to access the Email id

Source of Support: None, Conflict of Interest: None

PMID: 17642553

Rights and PermissionsRights and Permissions

Background: Dandruff is a common condition in clinical practice. We undertook a study to evaluate the efficacy and safety of a combination of zinc pyrithione and polytar in a shampoo base for the treatment of dandruff. Methods: A combination of polytar (1%) and zinc pyrithione (1%) was used for 4 weeks to treat 954 patients suffering from mild to severe dandruff. Scoring of dandruff was done on a 0-10 scale for each of the 6 regions of scalp at weeks 0, 2, 4 and 6. Follow up was for 2 weeks. Results: There was consistent improvement in dandruff scores over the treatment and the follow up period. There was significant improvement in signs and symptoms such as erythema and itching, with a negligible adverse event profile. The global assessment by investigators showed good-excellent results in the majority of patients and there was high acceptability for the treatment among the patients. Conclusion: A combination shampoo of polytar (1%) and zinc pyrithione (1%) offers a safe and effective option in the treatment of dandruff and its associated symptoms.


Print this article     Email this article

Online since 15th March '04
Published by Wolters Kluwer - Medknow