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Year : 2004  |  Volume : 70  |  Issue : 1  |  Page : 18--19

Sweat function in the diabetic foot

1 Departments of Dermatology, PSG, Institute of Medical Sciences and Research Centre, Coimbatore, India
2 Departments of Biostatistics, PSG, Institute of Medical Sciences and Research Centre, Coimbatore, India

Correspondence Address:
C R Srinivas
Deparment of Dermatology, PSG Hospital, Peelamedu, Coimbatore - 641004
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Source of Support: None, Conflict of Interest: None

PMID: 17642551

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Background: Autonomic dysfunction, an early manifestation of diabetic neuropathy, presents with altered sweating patterns, leading to dryness and fissuring. We conducted a study to assess the sweat function in the diabetic foot and to determine the interrelation between the duration of diabetes, sensation, fissuring, and sweating. Methods: The sweat function was assessed in 30 diabetic patients, 28 of whom had fissuring of the feet, using Ninhydrin impregnated discs. Results: There was a significant association between fissuring and sensation, but not between the duration of diabetes and fissuring and between loss of sweating and fissuring. In 18 patients (60%) there was impairment or absence of sweating in the presence of normal sensation. Conclusion: Although fissuring increases with long-standing diabetes and sweating is reduced in diabetic patients with fissures on the foot, the correlation between these entities was not statistically significant. Since 60% patients had altered sweating in the presence of normal sensations, the sweat test can be used as an early indicator of diabetic neuropathy.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow