Brand-Ad-30-6
 IADVL
Indexed with PubMed and Science Citation Index (E) 
 
Users online: 1932 
     Home | Feedback | Login 
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
  Navigate here 
  Search
 
   Next article
   Previous article 
   Table of Contents
  
 Resource links
   Similar in PUBMED
  Related articles
   [PDF Not available] *
   Citation Manager
   Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
* Registration required (free)  

 
  In this article
    Abstract
    Introduction
    Case Report
    Laser Basics
    Discussion
    References

 Article Access Statistics
    Viewed14644    
    Printed230    
    Emailed21    
    PDF Downloaded0    
    Comments [Add]    
    Cited by others 1    

Recommend this journal

 
DERMATO SURGERY
Year : 2002  |  Volume : 68  |  Issue : 2  |  Page : 94-95

Treatment of nevus of OTA by Q-switched, frequency doubled, ND: Yag laser


Bangalore, India

Correspondence Address:
National Skin and Hair Care Centre, 10/1, Cornwell Road, Longford gardens, Bangalore-560 025, India

   Abstract 

Nevus of Ota is a dermal melanocytic nevus for which hitherto no effective therapy was available. Lasers have been successfully tried for ablation. But there is no Indian experience till date. Q- Switched, Frequency Doubled, Nd: YAG Laser was installed at our centre an year ago. The first operated case, which has shown near complete pigment dilution, is being presented. The patient underwent three treatments with a minimum of 2 months between sessions. Pre and post therapy photographs were taken and side effects documented. The patient has shown near complete pigment dilution after 3 treatments. Q-Switched, Frequency Doubled, Nd: YAG Laser is effective in treating Nevus of Ota in the Indian skin types. There are no complications noticed till date in our experience.

How to cite this article:
National Skin and Hair Care Centre, Omprakash H M. Treatment of nevus of OTA by Q-switched, frequency doubled, ND: Yag laser. Indian J Dermatol Venereol Leprol 2002;68:94-5


How to cite this URL:
National Skin and Hair Care Centre, Omprakash H M. Treatment of nevus of OTA by Q-switched, frequency doubled, ND: Yag laser. Indian J Dermatol Venereol Leprol [serial online] 2002 [cited 2020 Oct 22];68:94-5. Available from: https://www.ijdvl.com/text.asp?2002/68/2/94/12607



   Introduction Top

Nevus of Ota is a dermal melanocytic nevus usually manifesting in the early childhood and progressively increasing in size and color till puberty. The nevus rarely regresses and disfigures the face and psyche of the patient. Occasionally malignant melanoma has been reported in the nevus. The present case report discusses the usefulness of Q-Switched, Frequency doubled Nd: YAG Laser therapy in treating this condition.

   Case Report Top

A 40-year school teacher with history of brownish pigmentation over the left cheek, present since birth was the first case treated with Q-Switched, Frequency doubled Nd- YAG Laser. The patient's skin type was Fitzpatrick V. The brownish pigmentation was confined to the left maxillary area. No ocular involvement was present.
The Q-Switched, Frequency Doubled Neodymium: Yttrium Garnet (QSFD Nd-YAG) Laser [MEDLITE-IV, manufactured by Continuum Biomedical, Bublin, California] has treatment repetition rates: 1, 2, 5 and 10 Hertz and spot size: 3, 4, 6 and 8 mmk at 1064nm. At spot size 3mm the maximum fluence is around 14J/cm2- The pulse duration of the laser is in the range of 1040.
The laser ablation was done in three sessions' using Q-Switched, Frequency doubled, Nd-YAG laser with the following treatment parameters [Table - 1].
Topical EMLA cream was applied under occlusion for 1 hour prior to laser therapy. The patient during the procedure experienced slight stinging sensation. In the post procedure period there was mild purpura and edema. This usually settled by about 2 to 3 days.
The lasered area developed hypopigmentation, after about a week. This was followed by post inflammatory hyperpigmentation, which started after 2 to 3 weeks and persisted on an average for 2 to 3 months. The pigmentary change was effectively tackled by sunscreens, hydroquinone in conjuction with topical corticosteroids.
Nevus resolved in three sessions of Qswitched, Frequency doubled, Nd-YAG laser ablation without any complications. [Figure - 1], [Figure - 2], [Figure - 3], [Figure - 4], [Figure - 5] & [Figure - 6]

   Laser Basics Top

Lasers are monochromatic electromagnetic radiation source used to treat various skin disorders.[2] Of the various lasers used to treat the dermal pigmentary dosorders the Q-switched Nd-YAG (1064nm), Ruby (694nm) and Alexandrite (755nm) lasers are best suited because they selectively target the melanosomes in the melanocytes and that too in the dermis. This is because of their longer wavelength, which facilitates dermal penetration. Melanin's broad absorption spectrum (from 250-1200nm) makes it a good target for laser light.[3]
The fundamental principle behind laser removal of cutaneous pigment is the GrothusDraper Law which states that absorption of the laser light is necessary for any ensuing mechanical or chemical alteration to occur. Secondly the laser source should have a suitable wavelength so as to reach the target at a specified length in the skin. Third the laser should confine the thermal damage within the melanosomes without heat diffusion to the adjacent structures after absorption by the chromophore i.e, melanosome. This is the thermal relaxation time. Thermal relaxation time is defined as the time it takes for half of the heat absorbed by the targeted chromophore to dissipate to the surrounding tissue. Melanosomes have short thermal relaxation time in the range of 50-100ns.
A given laser system will deliver its energy, which is of a specific wavelength. This laser output can be continuos or pulsed. This means that the energy can be delivered continuously or only for a few fractions of seconds in a repetitive manner. This is known as pulsed laser. If the pulse duration is less than the Thermal relaxation time of a given target then the specificity of the laser increases. This pulsing can be done by Q-Switching. Qstands for quality. Q switching is a means of shuttering the laser output so that it is delivered in extremely short of high-intensity radiation. The duration is in the nanosecond range about 10 nanoseconds for the Q-switched Nd-YAG laser.[4]

   Discussion Top

Literature is replete with therapies for Nevus of Ota like cryosurgery, dermabrasion to name a few. These therapies are associated with long standing complications like scars.[5] With the advent of lasers this had changed for good. Q-switched Lasers like Nd-YAG, Ruby and Alexandrite Lasers have proven effective in treating dermal melanocytic nevus of Ota.
The purpose of publishing this case is to report the efficacy of Q-switched Nd-YAG laser in successfully treating Nevus of Ota in an Indian patient. There are many doubts raised about its efficacy in skin types of IV-VI. But this case report lightens these apprehensions.
Even though this is a single case report since the starting of the centre in December 1999 till date nearly 14 cases are under therapy. All cases are in various stages of resolution of pigmentation. All cases had postoperative mild purpura, post therapy hypopigmentation and post inflammatory hyperpigmentation, which were transient. None of the cases treated have shown any skin textural changes. 

   References Top

1.Horue Suzuki. Clinical use of Q-Switched Nd: YAG loser for treatment of dermal and epidermal pigmented lesions, The 8th Congress of International YAG Laser Symposium, 1994,Oct 2-3.  Back to cited text no. 1    
2.Niwat Polnikorn. Basic laser principles In: Textbook of Cutaneous Loser Therapy (Niwat Polnikorn), 1st edn. Bangkok, Thailand: Holistic Publishing Co. Ltd, 2000;1 -24.  Back to cited text no. 2    
3.Anderson RR, Parish JA. The optics of human skin. J Invest Dermatol 1981;77:13-19.  Back to cited text no. 3    
4.Kilmer SL. Short pulsed lasers remove tatoo lesions. Dermatology Times 1993;14:9.  Back to cited text no. 4    
5.Stratigos AJ, Dover JS, Arndt KA. Laser treatment of pigmentary lesions-2000, Arch Dermatol 2000;136:915-921.  Back to cited text no. 5    

 

Top
Print this article  Email this article
Previous article Next article

    

Online since 15th March '04
Published by Wolters Kluwer - Medknow