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Year : 1998  |  Volume : 64  |  Issue : 4  |  Page : 180--182

Antigen mapping in hereditary epidermolysis bullosa

Department ot Skin and STD, Kasturba Hospital, Manipal - 576119, India and from the Department of Immuno- Dermatology, St. Thomas Hospital, London

Correspondence Address:
C R Srinivas
PSG Institute of Medical Sciences, Coimbatore - 614004

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Source of Support: None, Conflict of Interest: None

PMID: 20921757

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Standard immunofluorescence tests are not positive in the various inherited epidermolysis bullosa (EB). Using antibodies to known antigens present in the basement membrane zone, antigen mapping can be done by immuno fluorescence, to determine the level of blistering and establish the diagnosis. We report three cases of junctional EB and one case of dystrophic EB in whom the diagnosis was confirmed by antigen mapping.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow