Brand-Ad-30-6
 IADVL
Indexed with PubMed and Science Citation Index (E) 
 
Users online: 3957 
     Home | Feedback | Login 
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
  NAVIGATE Here 
    Next article
    Previous article
    Table of Contents

 RESOURCE Links
    Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed39    
    Printed0    
    Emailed0    
    PDF Downloaded2    
    Comments [Add]    

Recommend this journal

 

 ORIGINAL CONTRIBUTION
Year : 1998  |  Volume : 64  |  Issue : 4  |  Page : 176--179

A comparison of systemic photochemotherapy with 8- methoxypsoralen (8-mop) and with trimethylpsoralen (tmp) in vitiligo


Department of Dermatology, T N Medical College, BYL Nair Hospital, Mumbai- 400 008, India

Correspondence Address:
Vandana P Mhaske
Department of Dermatology, T N Medical College, BYL Nair Hospital, Mumbai- 400 008
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


PMID: 20921756

Rights and PermissionsRights and Permissions

Oral 8-MOP and TMP were compared in the PUVA therapy for vitiligo. Group A (25 c.ases) was initiated on 0.3 mg/kg of 8-MOP with 1 /2 Joule/cm[2] of UVA and weekly increments of 1 /2 Joule/ cm[2] and Group B was started on 0.6 mg/kg of TMP with 1 Joule/cm[2] of UVA and weekly increments of 1 Joule/cm[2], Therapy was given thrice a week. Repigmentation was evaluated by using a 0-6 scale. At the end of 60 sittings, an acceptable cosmetic response wasseen over the face, neck and upper extremities in both groups, while trunk and lower extremities showed lesser response. 8-MOP gave earlier response, needing a lowercumulative UVA dose i.e. 75 J/ cm[2] as compared to TMP i.e. 106 J/cm[2]. Phototoxicity was seen more often with 8-MOP. In conclusion, in Indians, 8-MOP is the drug of choice in PUVA therapy of vitiligo provided precautions against phototoxicity are adequate.






[PDF]*


        
Print this article     Email this article

Online since 15th March '04
Published by Wolters Kluwer - Medknow