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Year : 1998  |  Volume : 64  |  Issue : 1  |  Page : 17--22

The efficacy of flutamide, an antiandrogen in idiopathic hirsutism

Department of Skin and VD, Deccan College of Medical Sciences, Princess Esra Hospital, Shah Ali Banda, Hyderabad, A.P, India

Correspondence Address:
V K Somani
‘Sanskar’, 2-1-438/A Nallakunta, Hyderabad 500 004
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Source of Support: None, Conflict of Interest: None

PMID: 20921703

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The efficacy of flutamide, an antiandrogen in idiopathic hirsutism was studied. The long term effects of treatment with low doses of flutamide on clinical and hormonal parameters were investigated. Nine patients with idiopathic hirsutism were studied basally and during treatment with 125mg flutamide thrice daily for a period of 9 months. Safety parameters were assessed throughout the study. Hirsutism was graded by Femiman and Gallwey score and hormones were evaluated basally and later quarterly. After three months of therapy, flutamide had caused a significant alleviation of hirsutism and this continued during the subsequent months. No clinical significant side effects were observed during the period of the study. Biochemical and hormonal parameters remained unchanged after 9 months of flutamide.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow