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Year : 1994  |  Volume : 60  |  Issue : 1  |  Page : 5--7

Influence of liposomal drug entrapment on the performance of corticosteroid creams

Correspondence Address:
G U Rao

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Source of Support: None, Conflict of Interest: None

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Skin blanching and clinical efficacy of a liposomally entrapped Triamcinolone acetonide (TRMA) cream was compared with that of the conventional TRMA cream in healthy human volunteers and eczema patients respectively. Both the creams showed equal efficacy in eczema patients. A significant reduction in the skin blanching response with the liposomal TRMA cream as compared to the conventional TRMA cream suggests a decrease in the systemic absorption of the corticosteroid with the former.

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Online since 15th March '04
Published by Wolters Kluwer - Medknow