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Year : 1994  |  Volume : 60  |  Issue : 1  |  Page : 26-27

Surgical treatment in acrofacial vitiligo

Correspondence Address:
H Bharat Shah

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A total 18 patients of stationary acrofacial vitiligo, relatively resistant to medical treatment, of various age were selected for blister grafting. Duration of their disease varied from 3 to 10 years. The autografts were taken up and cosmetically acceptable result were seen in approximately 90% of the cases during the follow up period varying from 6 months to 2 years.

Keywords: Vitiligo, Acrofacial, Blister grafting

How to cite this article:
Shah H B, Joshipura P S, Thakkar K J. Surgical treatment in acrofacial vitiligo. Indian J Dermatol Venereol Leprol 1994;60:26-7

How to cite this URL:
Shah H B, Joshipura P S, Thakkar K J. Surgical treatment in acrofacial vitiligo. Indian J Dermatol Venereol Leprol [serial online] 1994 [cited 2020 Oct 22];60:26-7. Available from:

  Introduction Top

Acrofacial vitiligo exhibits poor response to all kinds of medical treatment modalities, viz. PUVA sol therapy, steroids human placental extract etc. We tried to treat 18 patients of resistant stationary acrofacial vitiligo with modified epidermal grafting by blister method.

  Materials and Methods Top

18 patients of various age were selected for this result oriented method. The lesions were non-progressive and resistant to traditional medical treatment. A prior consent of the patient was obtained before dermatosurgery was planned. A suction blister cup with pressure of 200 to 300 mm/ hg. was placed on shin of tibia, shoulders and arm for 2 hours to develop blisters on these locations. The vitiliginous skin was removed by superficial dermabrasion under local anesthesia and roof of blister from donor area (epidermal graft) was taken and grafted on recipient site. Antibiotic dipped occlusive dressing was done. Patients were followed up after 15 days, 3 months and 6 months, intervals.

  Results Top

During the follow up period varying from 6 months to two years, cosmetically acceptable result was as follows

100% in 27.8% cases

80 to 90% in 61.1% cases

Less than 80% in 11.1% cases

  Comments Top

Acrofacial vitiligo is difficult to treat with routine line of medical therapy. [2],[3] Micropunch grafting in not possible to treat vitiligo on lips. Tatooing is an alternative, but improper camouflaging and disappearance of pigment after long time create asthetic problems. Melanocyte culture is still in its initial stage. In our experience, the present method is a good alternative and preferable for treatment of acrofacial vitiligo.

  References Top

1.Norlund JJ, Learner A B. Vitiligo : What is it? Is it important? JAMA 1978; 239 : 1183-7.  Back to cited text no. 1    
2.Falabella R. Repigmentation of segmental vitiligo by autologous minigrafting. J Am Acad Dermatol 1983 ; 9 : 514-21.  Back to cited text no. 2  [PUBMED]  
3.Falabella R. Repigmentation of stable leukoderma by autologous minigrafting. J Dermatol Surg Oncol 1985 ; 12 : 118-9.  Back to cited text no. 3    


[Table - 1]

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1 Autologous melanocyte transfer via epidermal grafts for lip vitiligo
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International Journal of Dermatology. 2006; 45(6): 747-750
2 Autologous transplantation techniques for vitiligo: How to evaluate treatment outcome
Van Geel, N.A.C., Ongenae, K., Vander Haeghen, Y.M.S.J., Naeyaert, J.M.
European Journal of Dermatology. 2004; 14(1): 46-51
3 Epidermal grafting in vitiligo: Influence of age, site of lesion, and type of disease on outcome
Gupta, S., Kumar, B.
Journal of the American Academy of Dermatology. 2003; 49(1): 99-104
4 Epidermal grafting for vitiligo in adolescents
Gupta, S., Kumar, B.
Pediatric Dermatology. 2002; 19(2): 159-162
5 A systematic review of autologous transplantation methods in vitiligo
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Archives of Dermatology. 1998; 134(12): 1543-1549


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