|Year : 1992 | Volume
| Issue : 6 | Page : 393-394
SM Dhaded, PV Havaldar, BM Siddibhavi, VD Patil, M
S M Dhaded
Source of Support: None, Conflict of Interest: None
Collodion baby is a rare congenital disorder characterized by parchment like taught membrane covering the whole body. Other findings in our case include ectropion, eversion of lips, and flattening of nose and ears. Skin biopsy showed features consistant with the diagnosis of collodion baby. The child was treated with supportive measures like antibiotics, intravenous fluids, humidification, and application of emollients.
Keywords: Collodion baby. Ectropion, Eclabium
|How to cite this article:|
Dhaded S M, Havaldar P V, Siddibhavi B M, Patil V D, M. Collodion baby. Indian J Dermatol Venereol Leprol 1992;58:393-4
| Introduction|| |
Collodion baby is a rare congenital disorder resembling harlequin foetus but milder in degree. Collodion babies occur uncommonly although not as rarely as the harlequin baby. 
We report a case
| Case Report|| |
A 4 days old baby boy born at term to a consanguineous couple presented with complaint of membrane over the whole body, which started breaking on the second day. On examination the whole body was covered with parchment-like membrane [Figure - 1] resembling collodion and was peeling off on the chest and abdomen. Associated findings included ectropion, eversion of lips, flattening of nose and ears, claw-like hands, and limitation of joint movements. There were no other congenital anomalies. Hair and nails were normal. Routine blood and urine analysis were within normal limits. V D R L test was negative. Skin biopsy showed findings suggestive of collodion baby with epidermal hyperkeratosis and preservation of granular layer [Figure - 2].
Baby was treated ,n humidified environment with intravenous fluids, and prophylactic antibiotics. Emollient was applied to the whole body. Baby recovered well and was discharged with advice for regular emollient application and check up.
| Comments|| |
Collodion baby be a manifestation of various conditions [Table 1],  but often it is a manifestation of lamellar. ichthyosis. Incidence of this condition is 1 in 300,000 live births.  Collodion baby represents difficult treatment challenge, because of prematurity, dehydration, temperature instability, and infection.  Therefore supportive care is most important to prevent mortality. Skin can be made soft and moist by applying emollients. The point to be remembered is to avoid urea containing agents because of chances of developing high plasma urea levels. Other drugs that are toxic like salicylates and retinoids should be avoided.  sub There is no need to operate immediately for ectropion as it can be corrected by local application of clobetasol in older children. 
| References|| |
|1.||Nancy BE, Lawrence MS. Congenital and hereditary disorders of the skin. In: Schaffers Diseases of Newborn (Taeusch, Ballard, Avery, eds), 6th edn. U S A : W B Saunders, 1991; 973-84. |
|2.||Shwayder T, Ott F. All about ichthyosis. Paediat Clin N Am 1991; 38: 835-57. [PUBMED] |
|3.||Beverley DW, Wheeler D. High plasma urea concentration in collodion babies. Arch Dis Child 1986; 61: 696-8. [PUBMED] |
|4.||Sarojini PA, Roy N. Treatment of ectropion in lamellar ichthyosisr Ind J Dermatol Venereol Leprol 1991; 57: 55. |
[Figure - 1], [Figure - 2]