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Year : 1990  |  Volume : 56  |  Issue : 3  |  Page : 221-222

Eye changes in psoriatic arthropathy

Correspondence Address:
SP Chaudhari Ray

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Forty patients of psoriatic arthitis were examined for eye changes. Other than blepharitis seen in 2 patients and seitile cataract in 3 patients no eye changes could be elicited. Out of the, 18 patients HLA-B 27 was in 3 patients whereas Al and B 17 was in 6 and 9 patients respectively.

Keywords: Psoriasis arthropathy, Ophthalmological manifestations, HLA phenotyping.

How to cite this article:
Ray SC, Kaur I, Ram J, Kaur S. Eye changes in psoriatic arthropathy. Indian J Dermatol Venereol Leprol 1990;56:221-2

How to cite this URL:
Ray SC, Kaur I, Ram J, Kaur S. Eye changes in psoriatic arthropathy. Indian J Dermatol Venereol Leprol [serial online] 1990 [cited 2020 Oct 24];56:221-2. Available from:

Inflammatory lesions of the eye have been documented in a number of rheumatic diseases. Eye changes observed in patients with psoriatic arthritis include conjunctivitis, episcleritis and kerato-conjunctivitis sicca.[1],[2],[3] Rarely, uveitis has also been study documented in patients with psoriatic arthropathy[4],[5] The present study was undertaken to investigate the frequency of eye changes in psoriatic arthropathy, correlation with HLA phenotype, duration and severity of arthritis.

  Materials and Methods Top

Forty patients with psoriatic arthritis, according to the criteria of Moll and Wright,[6] were included in the study. In addition to the routine eye check up, slit lamp examination was also carried out in all patients. Antero-posterior and oblique X-ray views of the pelvis were done in 30 patients. In 18 patients blood was taken for HLA typing.

  Results Top

There were 28 males and 12 females in the age range of 18-60 years. Duration of psoriatic arthropathy ranged from 2-30 years. Two (5%) patients had blepharitis and 3(7%) had cataract. Out of 30 patients in whom X-rays of pelvis were taken 13(43.3%) patients revealed features of sacroileitis. HLA-A1, HLA-B17. HLA-B27 were positive in 6, 9 and 3 patients respectively. No correlation with eye changes was observed between the duration and the severity of the disease.

  Comments Top

Psoriasis involves the eye in approximately 10% of all cases. Most commonly, this involvement takes the form of blepharitis. [3] A non-specific conjunctivitis, sometimes with a considerable amount of secretion is fairly common.[3]],[6],[7] Healing may result in xerosis, symblepharon and trichiasis. Corneal involvement is rare[8] and lens changes are not usually noted with psoriasis.[3]

Some of the earlier studies[1],[2],[3],[4],[5] have observed varieties of eye changes in psoriatic arthritis. Baker et al[1] found episcleritis or conjunctivitis in 14 (23.3%) patients and iritis in one (1.6%) patient in a group of 60 patients. Lambart and Wright[2] found eye changes in the form of conjunctivitis in 19.6%, iritis in 7.1%, episcleritis in 1.8% and kerato-conjunctivitis sicca in 27%. Roberts et al[4] observed a higher incidence of uveitis in psoriatic patients. Jain et al[9] in a study of 90 psoriatics found squarnous blepharitis in 20%. However cataract in 7.7% and trachoma in 35.5% was considered to be incidental. In the present study, other than blepharitis and cataract no other changes were found. Cataract was considered to be of senile nature because of the older age of the patients and in the absence of a history of prolonged use of topical or systemic corticosteroids. Duke­Elder[10] also observed that the occurrence of cataract in psoriasis is coincidental. Lambert and Wright[2] noticed iritis in 15% patients having sacroileitis compared with 6% in patients without sacroileitis. Scarpa et al [11] could not elicit any eye changes in a group of 62 psoriatic arthritis patients. In contrast to the other studies[1],[2],[3],[4],[5] we found eye changes to be negligible in patients with psoriatic arthritis. As HLA phenoty, ing was done in a small number of cases it was found difficult to correlate with the type of eye changes observed.

  References Top

1.Baker H, Golding DN and Thompson M : Psoriasis and arthritis, Ann Int Med, 1963; 58 : 909-925.  Back to cited text no. 1    
2.Lambert JR and Wright V : Eye inflammation in psoriatic arthritis, Ann Rheum Dis, 1976; 35 : 354-­356.  Back to cited text no. 2    
3.Kaldeck R : Ocular psoriasis, Arch Dermatol (Suppl), 1953; 68 : 44-49.  Back to cited text no. 3    
4.Roberts MET, Wright V, Hills AGS et al : Psoriatic arthritis; follow up study, Ann Rheum Dis, 1976; 35 : 206-212.  Back to cited text no. 4    
5.Catsarou-Catsari A, katsambas A, Theodoropoulos et al : Ophthalmological manifestations in patients with psoriasis, Acta Dermato-Venereol (Stockh), 1984; 64 : 557-558.  Back to cited text no. 5    
6.Moll JMH and Wright V : Psoriatic arthritis, Semin Arthritis Rheum, 1973; 3 : 55-78.  Back to cited text no. 6    
7.Eustace P and Pierre O : Ocular psoriasis, Brit J Ophthalmol, 1970; 54 : 810-813.  Back to cited text no. 7    
8.Cram DL : Corneal melting in psoriasis (Letter to Editor) J Amer Acad Dermatol, 1981; 5 : 617.  Back to cited text no. 8    
9.Jain VK, Sood, S, Pahwa US et al : Ocular lesions in psoriatics, Ind J Dermatol Venereol Leprol, 1987; 53 : 33-34.  Back to cited text no. 9    
10.Duke-Elder WS : Psoriasis, in : Text Book of Ophthalmology, 1969; III : 732, 544-45, XI : 148­-149.  Back to cited text no. 10    
11.Scaroa R, Oriente P, Pucino A et al : Psoriatic arth ,s in psoriatic patients, Brit J Rheumatol, 1984; 23 : 246-249.  Back to cited text no. 11    


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