|Year : 1990 | Volume
| Issue : 2 | Page : 143-144
Sanjay Ghosh, B Haldar, A Biswas
Source of Support: None, Conflict of Interest: None
A 26 year old male had multiple asymptomatic very slowly growing, subcutaneous nodules on the limbs and trunk for the last 11 years. Histopathology revealed an encapsulated neoplasm consisting of mature fat cells intermingled with numerous blood vessels containing erythrocytes and fibrin thrombi.
|How to cite this article:|
Ghosh S, Haldar B, Biswas A. Multiple angiolipomas. Indian J Dermatol Venereol Leprol 1990;56:143-4
Angiolipomas are well circumscribed and subcutaneous, benign neoplasms. These usually appear after puberty on the trunk or limbs. Although clinically mimicking lipomas, they are often multiple and tender. Histopathologically mature adipose tissue with a varying number of blood vessels are seen. The degree of vascularity may range from a few angiomatous foci to dense vascular tissue. Both well-formed dilated capillaries, engorged with erythrocytes and tortuous capillaries with poorly formed lurnina, having prominent proliferation of pericytes may be visible within these angiomatous foci. Capillaries usually contain considerable amount of fibrin thrombi.
| Case Report|| |
A 26-year-old male had very slowly growing painless non-tender nodules on both the extremities and the trunk for the last 11 years. There were a total of 16 nodules varying from 1 to 2.5cm in diameter. These were soft, rounded and movable against the overlying skin. There was no evidence of infiltration into the deeper tissues. Family history was negative. There were no cafe-au-lait spots or axillary freckling. Clinical and laboratory investigations revealed no abnormality.
Histopathology revealed an encapsulated neoplasm consisting of mature fat cells along with numerous blood vessels. Well-formed dilated capillaries containing erythrocytes and fibrin thrombi and capillaries with ill-formed lumina and prominent proliferation of pericytes were visible [Figure - 1]
One large lesion (2.5 cm in diameter) was enucleated by conservative surgical excision. It did not recur during a follow-up period of 6 months. Other nodules are being observed at monthly intervals to detect any rapid growth or deeper infiltration.
| Comments|| |
Although angiolipomas are often tender and painful, our case was asymptomatic. A rare infiltrating, but still benign form of angiolipoma, usually occurring on a lower extremity, may invade the skeletal muscles and bones. If not widely excised, such lesions would recur. Histopathologically they simulate the non-infiltrating form.,, Hence, diagnosis and careful followup of angiolipoma is important.
| References|| |
|1.||Howard WR and Helwig EB : Angiolipoma. Arch Dermatol, 1960; 82 : 924-931. |
|2.||Lever WF and Schaumburg-Lever G : Histopathology of the Skin, 6th ed, JB Lippincott, New York, 1983; p 653-654. |
|3.||Lin JJ and Lin F : Two entities in angiolipoma, Cancer, 1974; 34 : 720-727. |
|4.||Stimpson N : Infiltrating angiolipomata of skeletal muscle, Brit J Sarg, 1971; 58 :464-466. |
|5.||Shal WJ Jr : Mobile encapsulated lipomas, Arch Dermatol, 1978; 114 : 1684-1686. |
[Figure - 1]