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Year : 1990  |  Volume : 56  |  Issue : 2  |  Page : 143-144

Multiple angiolipomas

Correspondence Address:
Sanjay Ghosh

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A 26 year old male had multiple asymptomatic very slowly growing, subcutaneous nodules on the limbs and trunk for the last 11 years. Histopathology revealed an encapsulated neoplasm consisting of mature fat cells intermingled with numerous blood vessels containing erythrocytes and fibrin thrombi.

Keywords: Angiolipoma

How to cite this article:
Ghosh S, Haldar B, Biswas A. Multiple angiolipomas. Indian J Dermatol Venereol Leprol 1990;56:143-4

How to cite this URL:
Ghosh S, Haldar B, Biswas A. Multiple angiolipomas. Indian J Dermatol Venereol Leprol [serial online] 1990 [cited 2021 Jan 17];56:143-4. Available from:

Angiolipomas are well circumscribed and subcutaneous, benign neoplasms. These usually appear after puberty on the trunk or limbs. Although clinically mimicking lipomas, they are often multiple and tender[1]. Histopathologically mature adipose tissue with a varying number of blood vessels are seen.[2] The degree of vascularity may range from a few angiomatous foci to dense vascular tissue. Both well-formed dilated capillaries, engorged with erythrocytes and tortuous capillaries with poorly formed lurnina, having prominent proliferation of pericytes may be visible within these angiomatous foci. Capillaries usually contain considerable amount of fibrin thrombi.[2]

  Case Report Top

A 26-year-old male had very slowly growing painless non-tender nodules on both the extre­mities and the trunk for the last 11 years. There were a total of 16 nodules varying from 1 to 2.5cm in diameter. These were soft, rounded and movable against the overlying skin. There was no evidence of infiltration into the deeper tissues. Family history was negative. There were no cafe-au-lait spots or axillary freckling. Clinical and laboratory investigations revealed no abnormality.

Histopathology revealed an encapsulated neoplasm consisting of mature fat cells along with numerous blood vessels. Well-formed dilated capillaries containing erythrocytes and fibrin thrombi and capillaries with ill-formed lumina and prominent proliferation of pericytes were visible [Figure - 1]

One large lesion (2.5 cm in diameter) was enucleated by conservative surgical excision. It did not recur during a follow-up period of 6 months. Other nodules are being observed at monthly intervals to detect any rapid growth or deeper infiltration.

  Comments Top

Although angiolipomas are often tender and painful,[1] our case was asymptomatic. A rare infiltrating, but still benign form of angiolipoma, usually occurring on a lower extremity, may invade the skeletal muscles and bones. If not widely excised, such lesions would recur. Histo­pathologically they simulate the non-infiltrating form.[3],[4],[5] Hence, diagnosis and careful follow­up of angiolipoma is important.

  References Top

1.Howard WR and Helwig EB : Angiolipoma. Arch Dermatol, 1960; 82 : 924-931.  Back to cited text no. 1    
2.Lever WF and Schaumburg-Lever G : Histo­pathology of the Skin, 6th ed, JB Lippincott, New York, 1983; p 653-654.  Back to cited text no. 2    
3.Lin JJ and Lin F : Two entities in angiolipoma, Cancer, 1974; 34 : 720-727.  Back to cited text no. 3    
4.Stimpson N : Infiltrating angiolipomata of skeletal muscle, Brit J Sarg, 1971; 58 :464-466.  Back to cited text no. 4    
5.Shal WJ Jr : Mobile encapsulated lipomas, Arch Dermatol, 1978; 114 : 1684-1686.  Back to cited text no. 5    


[Figure - 1]


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