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Figure 2: At low power, histologic evaluation of the punch biopsy reveals a dermal lesion composed of large cribriform glands and small infiltrating tubules (left,hematoxylin and eosin, ×40). At high power, the architecture and cytology of the cribriform glands was reminiscent of glandular breast tissue (middle,hematoxylin and eosin, ×200). A high power view of the epidermis overlying the dermal nodule reveals pagetoid spread of carcinoma cells (right, arrow, hematoxylin and eosin, ×200)

Figure 2: At low power, histologic evaluation of the punch biopsy reveals a dermal lesion composed of large cribriform glands and small infiltrating tubules (left,hematoxylin and eosin, ×40). At high power, the architecture and cytology of the cribriform glands was reminiscent of glandular breast tissue (middle,hematoxylin and eosin, ×200). A high power view of the epidermis overlying the dermal nodule reveals pagetoid spread of carcinoma cells (right, arrow, hematoxylin and eosin, ×200)