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Figure 2: UVB- Typical biological markers induced by UVB exposure (50 mJ/cm²) in normal human skin or reconstructed skin in vitro. Detection of cyclobutane pyrimidine dimers (CPD) immediately after exposure, and observation of Sunburn cells on HES staining and p53 protein accumulation at 24 hours (arrows). (CPD and Sunburn cells pictures: ×400; p53 pictures: ×200)

Figure 2: UVB- Typical biological markers induced by UVB exposure (50 mJ/cm²) in normal human skin or reconstructed skin <i>in vitro</i>. Detection of cyclobutane pyrimidine dimers (CPD) immediately after exposure, and observation of Sunburn cells on HES staining and p53 protein accumulation at 24 hours (arrows). (CPD and Sunburn cells pictures: ×400; p53 pictures: ×200)