IADVL
Indexed with PubMed and Science Citation Index (E) 
 
Users online: 3404 
     Home | Feedback | Reader Login
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
  NAVIGATE here  
     Search
     Current Issue
     Submit Article 
     My Preferences 
     Dermatology crossword 

 


Export selected to
Endnote
Reference Manager
Procite
Medlars Format
RefWorks Format
BibTex Format
  Access statistics : Table of Contents
   2006| January-February  | Volume 72 | Issue 1  
 
 
  Archives   Previous Issue   Next Issue   Most popular articles   Most cited articles
 
Hide all abstracts  Show selected abstracts  Export selected to
  Viewed PDF Cited
RESIDENT’S PAGE
Vitiligo: A sign of systemic disease
Richard H Huggins, Christopher A Janusz, Robert A Schwartz
January-February 2006, 72(1):68-71
DOI:10.4103/0378-6323.19730  PMID:16481722
Vitiligo reflects a systemic process that has important implications beyond the skin. These include other autoimmune diseases and ocular and neurological abnormalities. Alezzandrini syndrome and Vogt-Koyanagi-Harada syndrome particularly exemplify this relationship. In addition, vitiligo may be confused with other systemic disorders, including tuberous sclerosis, progressive systemic sclerosis (scleroderma), melanoma, and, in endemic regions, leprosy. We describe these associations and emphasize the importance of depigmenting disorders.
  32,133 1,150 14
CASE REPORTS
Lobster-claw hand: A manifestation of EEC syndrome
MJ Cyriac, E Lashpa
January-February 2006, 72(1):54-56
DOI:10.4103/0378-6323.19721  PMID:16481713
The combination of ectrodactyly, ectodermal dysplasia, and cleft lip with or without cleft palate (EEC syndrome) is a rare type of congenital anomaly. It usually occurs as an autosomal-dominant trait or less commonly in a sporadic form. In this complex, multiple congenital anomaly syndrome, any of the three cardinal manifestations may present with variable expressions.
  21,742 292 5
ORIGINAL ARTICLE
Comparison of the efficacy of topical 1% lindane vs 5% permethrin in scabies: A randomized, double-blind study
Omid Zargari, Javad Golchai, Abdolrasoul Sobhani, Ahmad R Dehpour, Shahriar Sadr-Ashkevari, Narges Alizadeh, Abas Darjani
January-February 2006, 72(1):33-36
DOI:10.4103/0378-6323.19715  PMID:16481707
Background: Permethrin, a pyrethroid insecticide, is not yet available in Iran and may be a useful substitute for the control of scabies in Iran. Aim: To compare the efficacy of topical lindane with topical permethrin in the treatment of scabies in a population in Iran. Methods: In a double-blind, randomized study, all consecutive patients with scabies were randomized into two groups. One group and their family contacts received 1% lindane cream, and the other group and their family contacts were treated with topical 5% permethrin cream. Subsequently, patients were followed up at 2- and 4-week post-treatment. Results: Of the 99 patients enrolled in the study, 47 patients received 1% lindane cream, and 52 patients were treated topically with 5% permethrin cream. Permethrin provided an improvement rate of 84.6% after two weeks, whereas lindane was effective only in 48.9% of patients. Conclusion: Permethrin (5%) cream was found to be significantly more effective in the treatment of scabies in comparison with lindane in this study, and it seems that it could be an alternative treatment.
  19,041 622 12
LETTER TO EDITOR
Turmeric (curcumin): A widely used curry ingredient, can contribute to oxidative stress in asian patients with acute vitiligo
Karin U Schallreuter, Hartmut Rokos
January-February 2006, 72(1):57-59
DOI:10.4103/0378-6323.19722  PMID:16481714
  19,144 462 14
VIEW POINT
Synthetic hairs: Should they be used?
Venkataram Mysore
January-February 2006, 72(1):5-7
DOI:10.4103/0378-6323.19710  PMID:16481702
Artificial hair fibers have recently been marketed in India as an alternative method of hair restoration. However, the subject of artificial hairs is controversial, as FDA in the United States has banned them. Several side effects have been reported after their use and it is therefore important that dermatologists are aware of all aspects about these devices. This article presents the author's viewpoint on the subject and suggests guidelines for using them.
  19,330 246 -
CASE REPORTS
Two cases of subungual glomus tumor
PS Murthy, R Rajagopal, PK Kar, S Grover
January-February 2006, 72(1):47-49
DOI:10.4103/0378-6323.19719  PMID:16481711
Glomus tumors are uncommon, small, painful, and usually benign hamartomas arising from the arterial end of the glomus body. They often present early in the subungual stage because of intense pain. Two female patients with subungual glomus tumor are reported here. The intense pain associated with this tumor had led to disuse atrophy of the upper limb in one case. Hildreth's sign and Love's test were positive in both, but imaging did not help in preoperative diagnosis. Tumors were resected by transungual approach, leaving a 3-mm-wide margin. There was no recurrence after 1-year follow-up in both instances.
  15,044 287 7
REVIEW ARTICLES
AIDS vaccine: Present status and future challenges
PK Nigam, Manjula Kerketta
January-February 2006, 72(1):8-18
DOI:10.4103/0378-6323.19711  PMID:16481703
Development of a preventive vaccine for HIV is the best hope of controlling the AIDS pandemic. HIV has, however, proved a difficult pathogen to vaccinate against because of its very high mutation rate and capability to escape immune responses. Neutralizing antibodies that can neutralize diverse field strains have so far proved difficult to induce. Adjuvanting these vaccines with cytokine plasmids and a "prime-boost," approach is being evaluated in an effort to induce both CTL and antibody responses and thereby have immune responses active against both infected cells and free viral particles, thereby necessitating fewer doses of recombinant protein to reach maximum antibodies titers. Although obstacles exist in evaluation of candidate HIV vaccines, evidence from natural history studies, new molecular tools in virology and immunology, new adjuvants, new gene expression systems, new antigen delivery systems, recent discoveries in HIV entry and pathogenesis, and promising studies of candidate vaccines in animal models have provided reasons to hope that developing a safe and effective AIDS vaccine is possible and within reach.
  13,858 1,370 3
LETTER TO EDITOR
Contact dermatitis to compound tincture of benzoin applied under occlusion
Chembolli Lakshmi, CR Srinivas
January-February 2006, 72(1):62-63
DOI:10.4103/0378-6323.19726  PMID:16481718
  13,912 135 3
EDITORIAL
Management of hemangiomas in children
SN Oak, Naveen Viswanath
January-February 2006, 72(1):1-4
DOI:10.4103/0378-6323.19709  PMID:16481701
  12,148 552 4
FOCUS
Thalidomide: Current status
Prashasti S Shanbhag, Vishalakshi Viswanath, RG Torsekar
January-February 2006, 72(1):75-80
DOI:10.4103/0378-6323.19732  PMID:16481724
  11,464 823 6
CASE REPORTS
Cutaneous mastocytosis: Report of six cases
Arun C Inamadar, Aparna Palit
January-February 2006, 72(1):50-53
DOI:10.4103/0378-6323.19720  PMID:16481712
Cutaneous mastocytosis is a rare infiltrative disorder of the skin. Though often asymptomatic, systemic features may be associated with any clinical pattern of the disorder at any age group. We present our experience with six cases of cutaneous mastocytosis, including three with diffuse cutaneous mastocytosis, a rare entity.
  11,895 387 4
GET SET FOR NET
Map of dermatology: Web image browser for differential diagnosis in dermatology
Maged N Kamel Boulos
January-February 2006, 72(1):72-74
DOI:10.4103/0378-6323.19731  PMID:16481723
  11,153 263 6
CASE REPORTS
Ichthyosis bullosa of Siemens: Response to topical tazarotene
S Rajiv, SV Rakhesh
January-February 2006, 72(1):43-46
DOI:10.4103/0378-6323.19718  PMID:16481710
In 1937, Siemens described a Dutch family with superficial blistering, flexural hyperkeratosis, and characteristic mauserung appearance. Since then, less than 20 kindreds with this condition have been described in the English dermatologic literature. A 14-year-old boy presented with history of recurrent blistering and peeling of skin since the age of 1 month, predominantly seen over limbs and trunk, often associated with secondary infection. His mother also had similar symptoms from childhood. On examination, the child had typical mauserung peeling of the skin and dirty gray hyperkeratosis in a rippled pattern over flexures. Skin biopsy from the boy showed intracorneal blistering with epidermolytic hyperkeratosis in the upper spinous layers. The typical history and clinical features along with characteristic histological findings confirmed our diagnosis of ichthyosis bullosa of Siemens. It must be differentiated from other conditions with epidermolytic hyperkeratosis and skin peeling, such as bullous ichthyosiform erythroderma of Brocq and peeling skin syndrome. Our patient responded well to 0.05% topical tazarotene gel over four weeks.
  8,475 233 6
LETTER TO EDITOR
Microdermabrasion for striae distensae
Rustom Tehrani
January-February 2006, 72(1):59-59
DOI:10.4103/0378-6323.19723  PMID:16481716
  7,780 455 1
ORIGINAL ARTICLE
Evaluation of functional impairment in psoriasis
Rohini Gaikwad, Sharmishtha Deshpande, Swati Raje, DV Dhamdhere, MR Ghate
January-February 2006, 72(1):37-40
DOI:10.4103/0378-6323.19716  PMID:16481708
Background: Psoriasis is a chronic disease, the course of which is punctuated by exacerbations and remissions. The impact of a chronic, relapsing, and disfiguring disease such as psoriasis on occupational, social, and other areas of functioning is substantial and needs attention. Aim: The purpose of this study was to assess the level and nature of functional impairment in psoriasis. Methods: Forty-three consecutive patients attending the dermatology clinic of a rural hospital were studied for psychiatric comorbidity and the level of functioning, using a semistructured questionnaire. Results: Psoriasis affected social functioning of 48% patients, led to decreased work efficiency in 51.1%, and to subjective distress at work in 62.8% of patients. Stress in home environment and interpersonal relationships was reported by 69.8%. Social and occupational functioning worsened with increasing severity of psoriasis after 1-year duration of illness. Patients complaining of pruritis frequently had anxiety disorders. Psychiatric comorbidity was detected in 67.4% cases. Conclusion : Substantial proportion of patients suffered deterioration of functioning, especially with increasing duration of illness. Thus, timely attention by dermatologists is needed in order to limit the disability caused by psoriasis. To achieve this, liaison with psychiatrist would be crucial along with illness education and emotional support.
  7,649 326 13
Correlation of clinical, histopathological, and microbiological findings in 60 cases of cutaneous leishmaniasis
Arfan ul Bari, Simeen ber Rahman
January-February 2006, 72(1):28-32
DOI:10.4103/0378-6323.19714  PMID:16481706
Background: In an endemic area, cutaneous leishmaniasis (CL) is largely diagnosed by its clinical appearance. Diagnostic challenge arises when the lesions appear in nonendemic area, when clinical picture is distorted, or any atypical variant is seen even in endemic regious. In developing countries like ours, the laboratory aid is not widely available and dermatologists mostly have to rely on clinical experience. Aim: The study was aimed to see the correlation of clinical, histological, and microbiological findings in clinically diagnosed cases of CL. Methods: It was an observational and descriptive study and was conducted over a period of 2 years in two dermatology centers in the country. Seventy-seven patients with clinically suspicious lesions of CL were screened and 60 of these were diagnosed as true clinical cases on the basis of criteria for clinical diagnosis. These cases were then subjected to slit skin smear and histopathological examination. Parasitologically positive and suggestive cases were recorded and descriptive statistics were used to evaluate the findings. Results: Out of 60 registered cases, 36 (60%) were smear-positive and 30 (50%) demonstrated Leishman Donovan (LD) bodies in histological sections. Twenty-six of the remaining (parasite-negative) cases showed one of the recognizable histological patterns seen in CL, 3 did not reveal any suggestive histology but responded to antimonial compound, and 1 turned out to be a case of deep mycosis. Conclusion: Considering the magnitude of the problem and limited resources of a developing country like ours, clinical diagnosis alone may be reliable enough in endemic areas.
  7,221 360 17
Vascular nevi in children
M Senthilkumar, Devinder Mohan Thappa
January-February 2006, 72(1):19-23
DOI:10.4103/0378-6323.19712  PMID:16481704
Background: Vascular nevi are cutaneous anomalies of angiogenesis and vasculogenesis resulting in various different clinical presentations. Aim: The purpose of our descriptive study was to observe the various types of vascular nevi in children and their features. Methods: A total of 4256 pediatric cases attending the dermatology OPD during the study period from August 2002 to August 2004 were screened for vascular nevi. Results: Out of these, 19 children (0.44%) had vascular nevi-17 hemangiomas of infancy (HOIs) and 2 port-wine stains. The mean age of the affected children was 1.3 years (ranging from 2.5 months to 8 years). There were 13 girls and 6 boys. Seventeen (89.5%) patients had progressing lesions and two (10.5%) had non-involuting ones. A solitary lesion was seen in ten (52.6%) cases and two to five lesions were present in five (26.3%) cases. The nevi were distributed over multiple sites in seven (36.8%) cases, the head and neck in six (31.6%) cases, the chest and lower limb in two (10.5%) cases each, and the upper limbs and genitalia in one (5.3%) case each. Among the hemangiomas of infancy, 15 (88.2%) cases of superficial type and 2 (11.8%) cases of deep type were seen. The cutaneous complications included ulceration in four cases and infection in one. Conclusions: HOIs were the most common vascular nevi of childhood.
  6,873 276 3
Parthenium dermatitis treated with azathioprine weekly pulse doses
Kaushal K Verma, Arika Bansal, G Sethuraman
January-February 2006, 72(1):24-27
DOI:10.4103/0378-6323.19713  PMID:16481705
Background: Parthenium dermatitis is a serious problem in India. Corticosteroids are the mainstay of treatment but the prolonged use of corticosteroids can cause serious side effects. Azathioprine used in daily doses has been shown to be effective. Aim: We have evaluated the effectiveness of azathioprine weekly pulse doses for the treatment of parthenium dermatitis. Methods: Twelve patients, ten males and two females, aged between 39 and 65 years (mean ± SD = 53.5 ± 8.7) having air-borne contact dermatitis to Parthenium hysterophorus for 3-19 years (mean = 6.33) were included in the study. The diagnosis in each patient was confirmed by patch-testing. The severity of the disease was determined by clinical severity score (CSS) on the basis of erythema, itching, type of lesions, and areas of body involved. Results: The pretreatment CSS in these patients varied from 29.7 to 55.5 (mean ± SD: 40.40 ± 7.95). After clinical and laboratory evaluation, the patients were treated with 300-mg azathioprine once-weekly doses for 6 months. Clinical and laboratory evaluations were repeated at weeks 1, 2, and then every 4 weeks until the end of therapy to evaluate the therapeutic response and side effects. The response was excellent (80-100% clearance of disease) in seven (58.33%) patients and good (60% clearance) in five (41.66%) patients. The post-treatment CSS decreased from the mean ± SD of 40.4 ± 7.95 to 10.9 ± 8.43 (P = 0.002). There were no significant side effects of the therapy. Conclusions: In this preliminary open study, azathioprine in weekly pulse doses has been found to be effective without any serious adverse effects in the treatment of parthenium dermatitis. The cost of therapy with this regimen is reduced by 60%.
  6,491 336 17
LETTER TO EDITOR
Nevus lipomatosus superficialis over neck, an atypical site
Jayanta Kr Das, Sujata Sengupta, Asok Kr Gangopadhyay
January-February 2006, 72(1):66-67
DOI:10.4103/0378-6323.19729  PMID:16481721
  6,038 146 3
Adenocarcinoma of the gall bladder presenting with a cutaneous metastasis
Jasleen Kaur, Tarun Puri, PK Julka, Gowthaman Gunabushanam, Venkateswaran K Iyer, Manoj K Singh, M Ramam
January-February 2006, 72(1):64-66
DOI:10.4103/0378-6323.19728  PMID:16481720
  6,017 147 7
Ultrasound biomicroscopy of the skin to detect a subclinical neuroma of the proximal nail-fold
Kalpana D Bhatt, Rui Fernandes, Rachita Dhurat
January-February 2006, 72(1):60-62
DOI:10.4103/0378-6323.19725  PMID:16481717
  6,016 141 1
Imatinib-induced nail hyperpigmentation in chronic myeloid leukemia
K Prabhash, Ghanshyam Biswas, N Prasad, Narayan Karant, PSRK Sastry, PM Parikh
January-February 2006, 72(1):63-64
DOI:10.4103/0378-6323.19727  PMID:16481719
  5,468 161 14
E-IJDVL
Epidermolysis bullosa acquisita
Jayanta Kr Das, Sujata Sengupta, Asok Kr Gangopadhyay
January-February 2006, 72(1):86-86
DOI:10.4103/0378-6323.19736  
  5,397 215 4
BOOK REVIEW
All about leprosy
BK Girdhar
January-February 2006, 72(1):85-85
  5,138 209 -
E-IJDVL
Recurrent, scarring penile ulcers
L Padmavathy, K Chockalingam, Lakshmana L Rao, N Ethirajan
January-February 2006, 72(1):86-86
DOI:10.4103/0378-6323.19738  
  5,179 100 5
QUIZ
Skin-colored nodules in zosteriform pattern
Ritika Gupta, Archana Singal, Deepika Pandhi
January-February 2006, 72(1):81-82
DOI:10.4103/0378-6323.19733  PMID:16481725
  5,078 141 -
CASE REPORTS
Chronic zosteriform cutaneous leishmaniasis
M Omidian, MA Mapar
January-February 2006, 72(1):41-42
DOI:10.4103/0378-6323.19717  PMID:16481709
Cutaneous leishmanasis (CL) may present with unusual clinical variants such as acute paronychial, annular, palmoplantar, zosteriform, erysipeloid, and sporotrichoid. The zosteriform variant has rarely been reported. Unusual lesions may be morphologically attributed to an altered host response or owing to an atypical strain of parasites in these lesions. We report a patient with CL in a multidermatomal pattern on the back and buttock of a man in Khozestan province in the south of Iran. To our knowledge, this is the first reported case of multidermatomal zosteriform CL. It was resistant to conventional treatment but responded well to a combination of meglumine antimoniate, allopurinol, and cryotherapy.
  4,979 136 7
E-IJDVL
Cutaneous metastasis from urologic tumors
Prabhash Kumar, N Prasad, G Biswas, PM Parikh
January-February 2006, 72(1):86-86
DOI:10.4103/0378-6323.19737  
  4,276 85 2
LETTER TO EDITOR
Stria distensae: Response by authors
Gurcharan Singh, Lekshmi P Kumar
January-February 2006, 72(1):59-60
DOI:10.4103/0378-6323.19724  
  3,730 125 -
QUIZ
Linear plaque over the face
S Veeranna
January-February 2006, 72(1):83-84
DOI:10.4103/0378-6323.19734  PMID:16481726
  3,609 132 -
EDITORIAL REPORT FOR 2004-2005
IJDVL is now indexed with PubMed
Uday Khopkar
January-February 2006, 72(1):87-88
  2,949 77 1
Ombudsman's Report for 2005
AK Bajaj
January-February 2006, 72(1):88-88
  2,687 67 -
Online since 15th March '04
Published by Wolters Kluwer - Medknow