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  Citation statistics : Table of Contents
   2003| May-June  | Volume 69 | Issue 3  
 
 
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CASE REPORTS
Urticarial vasculitis in infancy
S Kaur, GP Thami
May-June 2003, 69(3):223-224
PMID:17642893
Urticarial vasculitis is an uncommon manifestation of cutaneous vasculitis closely resembling chronic urticaria. It is an immune complex deposition disorder, which is not commonly observed in children. We report an 9-month-old infant with urticarial vasculitis and discuss its clinical course and differentiation from common urticaria.
  5 8,910 272
REVIEW ARTICLE
Serious cutaneous adverse drug reactions: Pathomechanisms and their implications to treatment
AC Inamdar, A Palit
May-June 2003, 69(3):205-208
PMID:17642887
Severe cutaneous adverse drug reactions pose diagnostic and therapeutic challenges to the medical community. Understanding the pathomechanisms can prevent their onset and improve their management, while timely and judicious intervention can reduce their mortality.
  4 7,404 601
CASE REPORTS
Ichthyosiform sarcoidosis following chemotherapy of Hodgkin’s disease
M Sawhney, YK Sharma, V Gera, S Jetley
May-June 2003, 69(3):220-222
PMID:17642892
Acquired ichthyosis in adults may reflect internal disease, viz. internal malignancy, especially Hodgkin’s lymphoma or sarcoidosis. We report a patient who developed ichthyosiform sarcoidosis over a year after completion of 6 cycles of combination chemotherapy for Hodgkin’s disease. To our knowledge, the development of ichthyosiform sarcoidosis after chemotherapy for Hodgkin’s disease has not been described earlier.
  3 8,718 119
STUDIES
Diltiazem vs. nifedipine in chilblains: A clinical trial
AK Patra, AL Das, P Ramadasan
May-June 2003, 69(3):209-211
PMID:17642888
Background: The treatment of chilblains remains unsatisfactory. Nifedipine in higher doses remains the mainstay of treatment. Aims: To compare the efficacy of diltiazem with that of nifedipine, and to determine the efficacy of nifedipine in lower doses, 36 chilblains cases were studied. Material and Methods: Group A (12 patients) was treated with diltiazem 60 mg thrice daily, and Group B (24 patients) with 10 mg nifedipine thrice daily till complete relief and then maintained on a sustained release preparation of nifedipine 20 mg twice daily. Results: Two patients in Group A showed complete relief in 7 days, and 3 patients in about 21 days, but in 7 cases there was little or no response. In group B, 21 cases showed 80-90% relief by the fourteenth day. Conclusions: We conclude that nifedipine remains the drug of choice in chilblains but can be used in a smaller dosage in the Indian population. Diltiazem is less effective in the conventional dose, which may be optimized.
  3 12,000 275
CASE REPORTS
Intralesional steroid induced histological changes in the skin
S Kaur, Amanjeet , GP Thami, H Mohan
May-June 2003, 69(3):232-234
PMID:17642897
Intralesional steroids are commonly used in dermatology. Besides their strong anti-inflammatory effects, the long acting steroids and other preservative agents may induce interesting histopatholoical changes, which may simulate focal mucinosis or a granulomatous pathology. A variety of histopathological changes induced by Intralesional injection of steroid in a lesion of keloid are being described.
  2 10,763 224
Sparfloxacin induced toxic epidermal necrolysis
M Ramesh, G Parthasarathi, B Mohan, AB Harugeri
May-June 2003, 69(3):235-236
PMID:17642898
Toxic epidermal necrolysis (TEN) is a life-threatening cutaneous adverse drug reaction. TEN is known to occur with the fluoroquinolone class of antibiotics, but only four cases of sparfloxacin induced TEN have been reported to the WHO database. This is another case report of sparfloxacin induced TEN.
  2 4,791 168
Localized cutaneous sporotrichosis lasting for 10 years
SK Rathi, M Ramam, C Rajendran
May-June 2003, 69(3):239-240
PMID:17642900
A case of localized cutaneous sporotrichosis lasting for 10 years is being reported. The fixed cutaneous variety creates diagnostic difficulty by mimicking other conditions, chiefly lupus vulgaris.
  2 4,691 135
LETTER TO EDITOR
Chronic pelvic inflammatory disease and melasma in women
M Sawhney, R Anand
May-June 2003, 69(3):251-252
PMID:17642906
  2 6,460 232
STUDIES
Utility of polymerase chain reaction as a diagnostic tool in cutaneous tuberculosis
L Padmavathy, L Rao, A Veliath
May-June 2003, 69(3):214-216
PMID:17642890
Background: Differentiation of cutaneous tuberculosis from other infective granulomas of the skin is difficult due to paucity of the organisms in tissue biopsies. Polymerase chain reaction (PCR) is a newer technique to identify the DNA of Mycobacterium tuberculosis in the tissues. Aim: We examined the utility of PCR as a tool for rapid diagnosis of cutaneous tuberculosis especially in cases negative by ZN staining and culture. Material and Methods: Twenty five random skin biopsies from patients with various types of cutaneous tuberculosis were subjected to PCR. Results: An overall positivity of 64% was observed, which is comparable to other series. Seventy five percent of lupus vulgaris cases, 62.2% of tuberculosis verrucosa cutis and 50% of scrofuloderma cases showed PCR positivity. Conclusion: Though useful, the cost and the technique involved limit the use of PCR in developing countries like ours.
  2 8,020 401
Therapeutic efficacy of intralesional triamcinolone acetonide versus intralesional triamcinolone acetonide plus lincomycin in the treatment of nodulocystic acne
BB Mahajan, G Garg
May-June 2003, 69(3):217-219
PMID:17642891
Background: Intralesional triamcinolone is an established therapy for cysts of acne. However, intralesional antibacterials have not been used earlier. Aim: To compare the efficacy of intralesional triamcinolone with that of a combination of intralesional lincomycin and intralesional triamcinolone in nodulocystic acne. Material and Methods: Ten patients of nodulocystic were injected with intralesional triamcinolone acetonide (2.5 mg/ml), while nine patients were given lincomycin hydrochloride (75 mg/ml) in addition to the intralesional triamcinolone. They were followed up 48 hrs, one week and one month later. Results: At one week, 7 patients (70%) treated with injection triamcinolone showed 66% improvement, whereas all 9 (100%) patients treated with lincomycin and triamcinolone showed 100% improvement which was stable at one month. Conclusion: A combination of intralesional triamcinolone and lincomycin is superior to intralesional triamcinolone alone in the treatment of nodulocystic lesions of acne.
  2 29,287 301
CASE REPORTS
Fever due to levamisole
R Gupta, S Gupta
May-June 2003, 69(3):237-238
PMID:17642899
Fever is rarely caused by levamisole. We report a 26-year-old woman who repeatedly developed fever 4-12 hrs after taking levamisole. The association was confirmed by repeated provocation tests.
  1 4,034 105
Koebner phenomenon in PLEVA
AC Inamdar, A Palit
May-June 2003, 69(3):226-226
PMID:17642894
Koebner phenomenon has been described in relation to many immunological, inflammatory and infectious dermatoses since the time of its first description. We report a man with pityriasis lichenoides et varioliformis acuta showing Koebner phenomenon.
  1 7,371 216
Familial acrogeria in a brother and sister
SM Ahmad, I Majeed
May-June 2003, 69(3):227-228
PMID:17642895
Acrogeria is one of the premature aging syndromes with an unknown mode of inheritance. Familial cases are quite rare. A report of the disease in a brother and sister demonstrating a possible autosomal recessive inheritance is described. An unusual finding was bilateral corneal opacities in both the patients.
  1 9,005 143
Cornelia de Lange syndrome
K Muhammed, B Safia
May-June 2003, 69(3):229-231
PMID:17642896
Two cases of Cornelia de Lange syndrome with similar phenotypic features are reported.
  1 27,377 366
PRESIDENTIAL ADDRESS
Presidential Address
AK Bajaj
May-June 2003, 69(3):204-204
PMID:17642886
  1 2,697 56
RESEARCH METHDOLOGY
Declaration of Helsinki: The ethical cornerstone of human clinical research
G Tyebkhan
May-June 2003, 69(3):245-247
PMID:17642902
  1 11,952 253
STUDIES
A comparative study of PUVASOL therapy in lichen planus
L Sharma, MK Mishra
May-June 2003, 69(3):212-213
PMID:17642889
Background: PUVA therapy is reported to be effective in lichen planus. However, PUVASOL therapy is more easily available in India. Aim: To carry out a three way open comparison of oral PUVASOL therapy with oral metronidazole and with the conventional oral antihistamine plus topical steroid therapy. Material and Methods: Seventy-five cases of lichen planus were studied for 12 weeks with three different modalities: 1. Oral metronidazole and topical emollient cream, 2. Oral PUVASOL and topical emollient cream, and 3. Oral cetirizine and topical betamethasone dipropionate cream. Lesions were assessed before starting the treatment and after every 4 weeks. Results: Seventy patients completed the trial. Statistical analysis showed that therapy 1 was less effective than 2 and 3, which were found to be equally effective. Conclusion: It is concluded that PUVASOL therapy is a useful alternative to conventional therapy in lichen planus in our country where sunlight is available in plenty.
  1 6,544 247
BOOK REVIEW
Colour atlas and synopis of paediatric dermatology
S Dhar
May-June 2003, 69(3):255-255
  - 4,856 126
EDITORIAL
IJDVL at the crossroads
U Khopkar
May-June 2003, 69(3):203-203
  - 3,434 63
LETTER TO EDITOR
Comments on “Serological study for sexually transmitted diseases in patients attending Std clinics in Calcutta”
S Dogra, B Kumar
May-June 2003, 69(3):252-253
PMID:17642907
  - 3,083 77
Response by the author
G Thawani
May-June 2003, 69(3):253-254
  - 3,130 77
Aggravation of preexisting dermatosis with Aloe vera
M Uppal, CR Srinivas
May-June 2003, 69(3):250-250
PMID:17642905
  - 5,065 203
Familial woolly hair in three generations
S Chidambara Murthy
May-June 2003, 69(3):250-251
PMID:17642904
  - 3,082 100
MEDICOLEGAL WINDOW
Drug eruptions and drug reactions
SP Sirur
May-June 2003, 69(3):248-249
PMID:17642903
  - 4,212 193
QUIZ
Quiz
SV Rakesh, DM Thappa
May-June 2003, 69(3):241-242
PMID:17642901
  - 6,543 282
Online since 15th March '04
Published by Wolters Kluwer - Medknow