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   2002| July-August  | Volume 68 | Issue 4  
 
 
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ORIGINAL ARTICLE
UVA and UVB in sunlight, Optimal Utilization of UV rays in Sunlight for phototherapy
P Balasaraswathy, Udaya Kumar, CR Srinivas, Shashidharan Nair
July-August 2002, 68(4):198-201
PMID:17656935
The disadvantages of sunlight as the source of UVA for phototherapy include variation with time, place, season, and atmospheric conditions. In the present study at Coimbatore, India we measured the UVa and UVB irradiance for one year using PMA 2100 meter. UVB irradiance was mazimum between 12.00 noon- 1.00 p.m (19.50w/cm2 to 40.2w/cm2) and UVA between 12 noon-1.15 p.m. (4.70mw/cm2 tp 6.59mw/cm2). The ratio of UVA was 1:500 to 1:600 during early hours and late evening and 1:200 during mid-day. At peak time (11.30 a.m. to 1.30 p.m.), the exposure time for 1 June of UVA was 2 min. 32 sec. to 4 min. 31 sec and for 10mj of UVB it was from 4 min. 55 sec. to 11 min. 22 sec. We recommend the ideal time for UVB phototheraphy between 11.00 a.m. to 2.00 p.m. and for PUVASOL between 9.30 a.m. to 11 a.m. and 2 p.m. to 3.30 p.m. when incidental UVB and infrared rays responsible for heat are less.
  29,564 1 8
CONTINUING MEDICAL EDUCATION
Pharmacological interventions for psoriatic arthritis: Present and future
KK Raja Babu
July-August 2002, 68(4):187-197
PMID:17656934
Psoriatic arthritis is a common, chronic inflammatory arthritis that affects 5-7% of patients with psoriasis. Psoriatic arthritis is often treated in the same manner and with the same drugs as rheumatoid arthritis is. Currently much attention is being focused on the role of agents that inhibit the activity of pro-inflammatory cytokines, such as tumor necrosis factor a, which are believed to play a key role in joint destruction. The objective of this article is to review these newer developments besides taking a fresh look at the existing methods of therapy of this potentially disabling disorder.
  14,779 0 1
HOW I MANAGE?
Vitiligo
DM Thappa
July-August 2002, 68(4):227-228
PMID:17656945
  11,068 0 1
ORIGINAL ARTICLE
Clinical variations in dermatophytosis in HIV infected patients
PK Kaviarasan, TJ Jaisankar, Devinder Mohan Thappa, S Sujatha
July-August 2002, 68(4):213-216
PMID:17656940
Dermatophyte infections are common in HIV infected patients and can occur at some point during their illness. They may show clinical variations. The present study was to note the prevalence and clinical variations in dermatophytosis in HIV infected patients. Out of 185 HIV infected patients screened at our hospital, the diagnosis of dermatophytosis was made in 41 cases. The prevalence of dermatophytosis was 22.2% Male to female ratio was 3:1 The mean age of our patients was 30.7 years. The occupations of our patients in decreasing order of frequency were labourers (43.9%), drivers (29.3%) and rest were housewives, commercial sex workers etc. Heterosexual route was the most common mode of acquisition of HIV infection. Tinea corporis was the commonest dermatophyte infection and was seen in 22 (53.7%) cases, followed by tinea cruris in 18 (49.9%), tinea pedis in 7 (17.1), tinea faciei in 6 (14.7%) and one patient had tinea manum infection. Tinea unguium was recorded in 11 cases. Out of the 22 patients with tinea corporis, 19 were in the HIV Group IV. Ten of them presented with multiple, large sharply marginated areas of hyperkeratosis resembling dry scaly skin (anergic form of tinea corporis). Proximal white subungual onychomycosis (PWSO), thought to be pathognomonic of HIV was seen in 3 cases only. This study has brought into focus variations in presentations of dermatophytosis.
  10,958 4 6
Efficacy of antioxidants as an adjunct to photochemotherapy in vitiligo: A case study of 30 patients
DP Jayanth, B Sathis Pai, SD Shenoi, C Balachandran
July-August 2002, 68(4):202-205
PMID:17656936
Low levels of antioxidant enzymes (catalase) have been demonstrated in the epidermis of vitiligo patients. Clinical trials with antioxidants as an adjunct to UVB phototherapy have shown encouraging results. The aim of this study was to determine the efficacy of oral antioxidants as an adjunct to photochemotherapy. Thirty patients of stable vitiligo, not on any treatment fort month were included in the study. Fifteen patients were treated with photochemotherapy alone and another 15 were treated with photochemotherapy and oral antiodixants (1 capsule od). Two index lesions were assessed in each patient, priorto treatment, 1 month and 3 months after treatment. Average area was calculated by Computer Aided Design. Patients were monitored for side effects to photochemotherapy and antioxidants. Percentage decrease in the area of index lesions was calculated after 3 months. No statistically significant difference was noted between the two regimes. No side effects specific to antioxidant therapy were observed. Antioxidants as an adjunct to photochemotherapy offer no distinct advantage and antioxidant therapy is free of adverse effects.
  9,941 1 -
CASE REPORT
Dilated pore of winer
RR Mittal, PS Sethi, Anju Jha
July-August 2002, 68(4):239-240
PMID:17656953
Two cases of dilated pore of Winer were observed. First case had single defined black papule with well defined margin, central pore and discharge of black powdery material from nose since 3 years. The second case had one 9mm, black well-defined papule with central pore discharging black powdery material on right forearm since 9 months and 9 similar smaller papules were seen on forearm and lower abdomen. Histopathologically both revealed greatly dilated infundibulum lined by acanthotic epidermis and atrophic subinfundibular hair structures thus confirming diagnosis of dilated pore of Winer
  9,638 0 -
ORIGINAL ARTICLE
Clinico-epidermiological studies on tinea versicolor
Gatha S Rao, Maria Kuruvilla, Pramod Kumar, Vimala Vinod
July-August 2002, 68(4):208-209
PMID:17656938
One hundred and twenty patients with tinea versicolor who attended the outpatient department of Dermatology, K.M.C Hospital, Mangalore were studied with reference to their clinical features, age and sex distribution, relation to climate and personal habits. The disease was commonest among the age group of 21-30 years (30%). It was found to be distributed predominantly over the neck (71.6%), chest (58.3%) and back (70%). Inmost of the patients, lesions were observed first and also aggravated during summer months. One fourth of the patients either had systemic diseases or were on immuno-suppressant drugs. The disease was continuous in spite of taking treatment in 21.6% of patients. 38.3% of patients gave a positive family history. Even though the disease is resistant to treatment, avoiding the predisposing factors like increased sweating, sharing the towels and clothes, malnutrition, synthetic clothings will help to control the disease.
  9,303 0 4
LETTER TO EDITOR
Weekly fluconazole in the treatment of tinea capitis
Asit Mittal, AK Khar, Suresh Jain, Anupam Sharma
July-August 2002, 68(4):247-247
PMID:17656957
  8,603 0 -
CASE REPORT
Dermatitis herpetiformis and rheumatoid arthritis
Archana Singal, Sambit Nath Bhattacharya, Manik Chandra Baruah
July-August 2002, 68(4):229-230
PMID:17656946
A 35- year-old deaf and dumb woman with clinical and histopothological diagnosis of dermatitis herpetiforrnis (DH) is reported for its rare association with rheumatoid arthritis (PA).
  8,430 0 1
SHORT COMMUNICATION
Many faces of Koebner phenomenon in psoriasis
Somesh Gupta
July-August 2002, 68(4):222-224
PMID:17656943
Two patients with unusual skin stimuli causing koebner phenomenon in psoriasis are reported. First patient, a 33 - year -old man, had psoriasis and multiple keloids for the last 26 - years. At few places, the lesions of psoriasis and multiple keloids for the last 26-years. At few places, the lesions of psoriasis healed with keloid formation, and psoriatic plaques appeared selectively on the top of the keloids in addition to palms, soles and scalp. In the second patient (a 67 - year -old man), the psoriatic lesions appeared at the site of healing herpes zoster lesions. Koebner phenomenon in psoriasis due to herpes zoster or varicella is rare, while that due to keloid has not been reported.
  8,330 2 4
CASE REPORT
Eccrine spiradenoma
AV Kaleeswaran, VR Janaki, G Sentamilselvi, C Kiruba Mohan
July-August 2002, 68(4):236-237
PMID:17656951
A case of eccrine spiradenoma, an uncommon tumour, in an adult woman is described herewith its clinical and histopathological features
  7,869 0 3
Blepharochalasis
RP Sharma, SP Singh, S Mithal
July-August 2002, 68(4):231-231
PMID:17656947
A-16-year old female with laxity, atrophy, wrinkling and telangiectases of skin of both upper eyelids is being reported. These changes were preceded by recurrent, painless edema of eye lids, starting at the age of 14 years.
  5,725 0 1
SHORT COMMUNICATION
Sezary syndrome - Without erythroderma
K Abdul Samad, K Prasanna Moorthy, P Akhar Ali
July-August 2002, 68(4):225-226
PMID:17656944
Sezary syndrome (SS), is described as the classical triad of pruritic erythroderma, lymphadenopathy, and presence of more than 10% of circulating Sezary cells in the peripheral blood. We report on unusual case of advanced cutaneous T - cell lymphoma with classical haematological and histopathological features of Sezary syndrome, but lacking the clinical features of erythroderma. A 66 year old man presented with asymptomatic multiple papules, plaques and nodules and with generalized lymphadenopathy. Peripheral smear showed more than 60% of Sezary cells. Skin and lymph node biopsy showed typical features of T-cell lymphoma and immunohistochemistry and CD marker studies showed the cells to be atypical T-lymphocytes. This unusual case is highlighted to denote that erythroderma need not be taken as a hard and fast criterion for diagnosing Sezary syndrome.
  5,672 0 -
ORIGINAL ARTICLE
Pattern of childhood STDs in a major hospital of East Delhi
CS Bhogal, S Chauhan, MC Baruah
July-August 2002, 68(4):210-212
PMID:17656939
Of the 1418 patients with STDs, who attended the STD clinic between January 1996 to December 2000, 50 (3.4%) were children below 14 years of age. Boys (29) were more than girls (21). Syphilis was the most common STD found in these children (46.8%), followed by vulvo-vaginal candidiasis (19.2%), condylomata acuminata (10.6%), gonorrhoea (8.5%), herpes progenitalis (6.4%), chancroid (4.3%), perianal candidosis and perianal molluscum contagiosum (2.1 % each). Three children had more than one STD. A history of sexual abuse could be elicited in 30 children (60%), none of the children were positive of HIV. All children with symptoms pertaining to their genitourinary system should be evaluated thoroughtly for sexual abuse.
  5,541 0 1
SHORT COMMUNICATION
Effect of phenytoin sodium in reducing blistering of epidermolysis bullosa report of four cases
CK Sasidharan, M Vijayakumar, MS Vinodkumor
July-August 2002, 68(4):217-219
PMID:17656941
To evaluate the effect of phenytoin in reducing of patients with epidermolysis bullosa four newborn babies were studied after thorough clinical evaluation including detailed history and relevant investigations. All of them were put on oral phenytoin sodium, in the usual antiepileptic dose and were followed up. All of the babies had significant reduction in the number of lesions.
  5,527 0 -
CASE REPORT
Cutaneous horn and thermal keratosis in erythema AB igne
Apra Sood, Sandeep Sharma, Neena Khanna
July-August 2002, 68(4):237-238
PMID:17656952
A 46 - year - old Kashmiri lady developed erythema ab igne on both legs. She subsequently developed multiple keratoses and a cutaneous horn in the involved skin. An uncommon association of these three clinical conditions is being presented.
  5,392 0 -
SHORT COMMUNICATION
Monilethrix
GR Narmatha, S Chithra, N Balasubramanian
July-August 2002, 68(4):220-221
PMID:17656942
Monilethrix is rare hereditary disorder which is in herited as autosomal dominant trit. We report two siblings with a combination of monilethrix and leukonychia.
  4,970 1 1
CASE REPORT
Glibenclamide induced photosensitivity
Archana Singal, SN Bhattacharya, MC Baruah
July-August 2002, 68(4):240-241
PMID:17656954
A 54 - year-old man with diabetes mellitus developed photodermatitis following ingestion of second generation sulphonylurea, glibenclamide. The case is being reported to highlight the infrequently reported side effect of glibenclamide.
  4,893 0 -
ORIGINAL ARTICLE
Ecologic perspective of dermatologic problems in North Eastern India
AK Jaiswal
July-August 2002, 68(4):206-207
PMID:17656937
In the nations of the developing world, the incidence of skin diseases is especially affected by geography. Epidemiological studies of skin diseases are important in the study of disease pattern, changes in disease pattern and for planning dermatology service and research for a country. This report records the pattern of skin diseases encountered in the North- East region of India. The incidence of non-infectious dermatoses was slightly higher than that of infectious dermatoses in this part of the country.
  4,874 0 1
CASE REPORT
Palmoplantar keratoderma in myxedema
RR Mittal, Anju Jha
July-August 2002, 68(4):242-242
PMID:17656955
A 45-years-old woman came with diffuse yellowwaxy thickening, dryness and scaly skin of palms and soles and thickening of knuckles on dorsa of hands since 2 years. In addition, she had hoarseness of voice, weight gain, slow response, intolerance to cold, loss of pubic and axillary hair, generalised dryness and coarseness of skin, and mask like fades. Diagnosis of palmoplantar keratoderma and myxedema was confirmed by investigations.
  4,825 0 -
Chromoblastomycosis
SK Sayal, GK Prasad, KZ Jawed, S Sanghi, S Satyanarayana
July-August 2002, 68(4):233-234
PMID:17656949
  4,811 0 1
LETTER TO EDITOR
Carbamazepine induced exfoliative dermatitis
Samir V Shah, JN Dava, Vikas Aggrawal
July-August 2002, 68(4):246-246
PMID:17656956
  4,154 0 1
CASE REPORT
Multiple leiomyoma
AV Kaleeswaran, G Sentamilselvi, VR Janaki, C Janaki
July-August 2002, 68(4):234-235
PMID:17656950
A case of asymptomatic multiple leiomyoma along with its histopathological features is described.
  4,074 0 -
Erythrokeratoderma variabilis
Asok Gangopadhyay
July-August 2002, 68(4):232-232
PMID:17656948
A case of erythrokeratoderma variabilis with classical clinical and histological features is being presented here.
  3,814 0 -
LETTER TO EDITOR
Immunotherapy in clinical practice - An evaluation
VV Pal, G Gaikwad, BM Khamaar, R Ganapati
July-August 2002, 68(4):248-248
PMID:17656959
  3,675 0 -
Comments on angiokeratoma of the tongue
DM Thappa, K Karthikeyan
July-August 2002, 68(4):247-247
PMID:17656958
  2,991 0 -
Online since 15th March '04
Published by Wolters Kluwer - Medknow