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   1997| January-February  | Volume 63 | Issue 1  
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A comparative study of liver function tests in patients of chronic liver disorders with and without cutaneous manifestations
SK Sayal, CM Gupta, AL Das, PK Chattwal
January-February 1997, 63(1):15-19
Forty six cases of chronic liver disorders with and without cutaneous manifestations were studied for abnormalities of liver function tests. 27 cases were associated with cutaneous manifestations and 19 cases without cutaneous manifestations. A higher serum bilirubin level was seen in all cases with cutaneous manifestations. Serum bilirubin was significantly high (P<0.05) in patients of chronic active hepatitis with cutaneous manifestations. Serum alkaline phosphatase and serum glutamic pyruvic transaminase (SGPT) levels were significantly high in chronic active hepatitis and alcoholic liver disease without cutaneous manifestations respectively.
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Lupus erythematosus panniculitis
Aloke Kumar Roy, Sadhan Kumar Ghosh, Debabrata Bandhyopadhyou, Jayasri Das
January-February 1997, 63(1):33-34
Lupus erythematosus panniculitis is a quite rare clinical entity characterised by one or several firm, asymptomatic, often fairly large subcutaneous nodules, as a manifestation of SLE or DLE. Two cases of lupus panniculitis, both female, are described here. Both of them had absence of typical lesions of SLE or DLE elsewhere in the body. Systemic symptoms were not present, antinuclear factor was positive in one case. Both showed typical lobular panniculitis on biospy and responded favourably to systemic chloroquine therapy.
  8,061 0 -
Erythroderma: a study of incidence and aetiopathogenesis
Ajay Chaudhary, Pushpa D Gupte
January-February 1997, 63(1):38-39
Thirty cases of exfoliative dermatitis (22 male and 8 female) were selected at random for study. In addition to routine history and clinical examination, investigations like histopathology of skin and lymph nodes, peripheral blood smear for abnormal cells and bone marrow examinations were done. Aetiologically, the cases could be classified into 4 categories namely exfoliation in per existing dermatoses, drug-induced exfoliation, idiopathic exfoliation and exfoliation secondary to internal malignancy. Two cases showed abnormal monocytoid cells (sezary cells) in peripheral blood smear.
  6,768 0 -
Thickening of peripheral nerves in neurofibromatosis
Asit Mittal, BL Masuria, LK Gupta, M Sharma, NK Bansal
January-February 1997, 63(1):63-64
A 14-year-old boy presented with multiple asymptomatic swellings all over the body. Cutaneous findings were classical for neurofibromatosis. Interesting and unusual finding was generalised thickening of peripheral nerve trunks. Biopsy from thickened nerve had features of neurofibromatosis.
  5,929 0 -
Hereditary spherocytosis presenting as indolent leg ulcers
K Muhammed, S Lilly, PH Shereef
January-February 1997, 63(1):55-57
Indolent leg ulcertation, which is the rarest manifestation of hereditary spherocytosis, started at the age of 5 years affecting a 15-year-old boy and his mother is reported. Review of literature showed very few reports from India and abroad. The response to oral folic acid was excellent
  5,806 0 -
Extent and pattern of paediatric dermatoses in rural areas of central India
Vikas Bhatia
January-February 1997, 63(1):22-25
A house to house study was done on 666 children aged 0-14 years in 5 villages of Wardha district in Maharastra (Central India). 346 children (51.95%) had one or more dermatoses. Infective dermatoses contributed 63.5% of all dermatoses, while noninfectious and nutritional deficiency dermatoses were responsibile for 21.2% and 15.2%, respectively. Pediculosis capitis was seen in 136 children (20.4%), followed by pyoderma in 107 (16.07%) and dematophytosis in 44 (6.61%). Scabies was found in only 6 and 4 cases of leprosy were also delected. Pityriasis alba, pityriasis capitis amond non-infectious; hair and skin changes among nutritional deficiency dermatoses were leading presentations.
  5,199 0 -
Hereditary sensory and autonomic neuropathy type I
RR Mittal, Shivali
January-February 1997, 63(1):40-41
Hereditary sensory and autonomic neuropathy (HSAN) type 1 is a rare hereditary neurological disorder. Two brothers aged 17 and 14 years had HSAN type 1 as both had big ulcers on feet, mutilation, dissociated anaesthesia, absent ankle jerks and normal hands. Probably these are first cases of HSAN type 1 in Indian literature.
  5,179 0 -
Cutaneous manifestations of HIV infection
Pramod G Bhandary, Narendra K Kamath, Ganesh S Pai, Gatha Rao
January-February 1997, 63(1):35-37
A total of 32 patients with HIV infection were examined for cutaneous manifestations from September 1994 to December 1995 in the Dermatology and Venereology Department of Wenlock District Hospital, Mangalore. Xerosis was the commonest skin manifestation (50%). Oropharyngeal candidiasis was an indicator of grave prognosis in 4 patients. Seborrhoeic dermatitis, seen is in 15.6%, presented in an atypical, extensive and rapidly evolving form. Infections were atypical, extensive and did not respond to conventional modalities of treatment.
  5,171 0 -
Pentoxifylline and ciprofloxacin in chronic folliculitis of legs
D Prasad, R Saini, KS Negi
January-February 1997, 63(1):9-10
Clinically diagnosed 38 patients of chronic superficial folliculitis were divided into 2 equal grops. Group I was given combination of ciprofloxacin and placebo for two weeks followed by placebo for another 4 weeks whereas patients in group II were given combination of ciprofloxacin and pentoxifylline for two weeks followed by pentoxifylline for 4 weeks. The combination of pentoxifylline with ciprofloxacin was found to be superior in initial response as well as prevention of reccurrence.
  4,947 0 -
Griseofulvin therapy in acne vulgaris
Surabhi Dayal, VK Jain
January-February 1997, 63(1):70-71
  4,683 0 -
Topical coal tar alone and in combination with oral methotrexate in management of psoriasis : a retrospective analysis
PVS Prasad, Felix John
January-February 1997, 63(1):26-28
Thirty five patients admitted with psoriasis were analysed. 16 patients received 20% crude coal tar and 19 patients received 20% crude coal tar along with methotrexate in a weekly oral schedule (15mg/wk). After 4 weeks of therapy there was total clearence in 52.6% of the patients with combination therapy, whereas only 12.5% of the patients with conventional therapy achieved this.
  4,426 0 -
Proteus syndrome
Avinash S Mayekar, Rajeshree G Chavan, Vaishali A Phadke, Rajiv Joshi, SL Wadhwa
January-February 1997, 63(1):44-46
A 2-year-old male child born of a nonconsanguineous marriage with high parental age presented with macrodactyly, dysmorphic features, large disfiguring lipomas, small fibromas, a linear verrucous epidermal naevus and lymphangioma circumscriptum. X-ray of hand revealed macrodystrophia lipomatosa progressiva. A lipoma and lymphangioma circumscriptum were confirmed by histopathology. The cosmetically disfiguring lipomas were excised. This is the first case report from India with the characteristic macrodactyly. This could possibly be the first case of report of a mutational disorder following intake of carbimazole during pregnancy.
  4,140 0 -
Bilateral naevus of OTA
Asok Kumar Gangopadhyay
January-February 1997, 63(1):50-52
Bilateral naevus of Ota is a rare condition. It is still more rare in males. Here is a report of such a case with review of literature.
  4,062 0 -
Porokeratosis of mibelli with a mucous membrane lesion
Asok Kumar Gangopadhyay
January-February 1997, 63(1):53-54
Mucous membrane lesion of porokeratosis is a very vary rare occurrence. Here is a case report of such a case.
  4,014 0 -
Pattern of skin diseases among civil population and armed forces personnel at Pune
SK Sayal, AL Das, CM Gupta
January-February 1997, 63(1):29-32
The pattern of skin disorders among 11393 civil and 8123 defence service personnel who attended out-patient department (OPD) from January 1989 to December 1994 is presented. Infective dermatoses were more common in civil population (41.2%) as compared to defence service personnel (36.3%). Fungal infection was common in both groups (15.1% and 17.2%) whereas parasitic infestations and pyoderma were more common in civil population (12.8% and 6.1%) as compared to service personnel (7.8% and 3.6%). Among non-infective dermatoses eczemas were more common in civil population (17.3%) as compared to Armed Forces personnel (11.7%), whereas papulosquamous disorders, pigmentary disorders, acne and alopecia were more common in Armed Forces personnel (13.5%, 13.4% 8.7% and 6.2%) as compared to civil population (10.8%, 10.1%, 6.4% and 4.1%). The incidence of other skin disorders did not differ much between the two groups.
  3,955 0 -
Lack of antinuclear antibody in children with atopic dermatitis
Sandipan Dhar, Amrinder J Kanwar, Shridhar D Deodhar
January-February 1997, 63(1):5-8
Antinuclear antibody (ANA) was assayed in 76 children with atopic dermatitis (AD) of which 46 were males and 30 females. Their ages ranged from 6 months to 12 years (mean 3.4 years). Age at onset of AD ranged from 2 months to 5.5 years (mean 1.9 years) and its duration ranged from 4 months to 4 years (mean 1.2 years). While facial lesions were present in 56 (73.3%) patients, 49 (64.5%) patients had predominant involvement of extensors. As per severity score designed by Rajka and Langerland, 31 (40.8%), 42 (55.3%) and 3 (3.9%) patients had mild, moderate and severe diseases respectively. History of photosensitivity was present in 6 (7.9%) patients. Serum samples were positive for ANA in a very low titre (1:20) in 2/6 patients with facial lesions. However LE cell, rheumatoid factor and C-reactive proteins were negative and serum complement levels were within normal limits.
  3,864 0 -
Atypical dyskeratosis congenita
SG S Krishnan, P Devakar Yesudian, M Jayaraman, VR Janaki, JM Boopal Raj
January-February 1997, 63(1):47-49
Dyskeratosis congenita is a syndrome characterised mainly by pigmentation and atrophy of skin, nail dystrophy and oral leucoplakia. We report a patient who had features consistent with this syndrome including skin atrophy and pigmentation, oral leucoplakia, oesophageal stricture, but with normal finger and toe nails. Even though many variants have been described in the literature sparing of the nails as in our patient is extremely uncommon.
  3,849 0 -
Pyoderma gangrenosum in HIV patient
SK Sayal, AK Malik, S Banerjee
January-February 1997, 63(1):58-60
Pyoderma gangrenosum (PG) has previously been reported in very few patients with HIV infection. We describe here a 30-year-old housewife with HIV infection having multiple ulcerations over lower limbs characteristic of PG.
  3,749 0 -
Treatment of stable and recalcitrant depigmented skin conditions by autologous punch grafting
Koushik Lahiri, SR Sengupta
January-February 1997, 63(1):11-14
Sixty cases of stable and refractory depigmented skin conditions which include local vitiligo, segmental vitiligo, chemical leucoderma, vitiligo vulgaris, post-burn depigmentation etc constitute the study group. 39 of them were female and 21 male. Age ranged between 6 and 67 years. 1057 grafts were placed over 114 lesions and the cases were followed up to a period of 18 months. 70% to 100% repigmentation was observed in 56 lesions of 31 patients. Rate and extent of perigraft pigment spread was noted. Patients under PUVASOL showed a distinctly better response. Sequelae like cobble-stoning and polka-dotting were found to be disappearing with time or interference.
  3,658 0 -
Reliance on single dose therapy for gonococcal urethritis
BD Sathyanarayana
January-February 1997, 63(1):61-62
This case report is to highlight the shortfall of single dose therapy for acute uncomplicated gonococcal urethrits and its later effects.
  3,546 0 -
Papillon lefevre syndrome
Bela Padhiar, Umesh Karia, Mona Shah, RC Rawal, FE Bilimoria
January-February 1997, 63(1):42-43
A 38-year-old Hindu female patient presented with palmoplantar keratoderma with premature fall of deciduous teeth. Clinical examination revealed diffuse hyperkeratosis of palms and soles. Upper incisor teeth were widely spaced and conical, while lower incisors were missing. X-ray was helpful in diagnosis.
  3,413 0 -
Hypomelanosis of Ito with rare neurological association
S Grover, K Dash, G Singh, V Venkateshwar, P Rodrigues
January-February 1997, 63(1):65-66
  3,385 0 -
IgG subclasses in pemphigus vulgaris
Amrinder J Kanwar, Gurvinder P Thami, Gursharan K Bedi
January-February 1997, 63(1):20-21
Direct immunofluorescence in perilesional skin of 13 pemphigus patients is studied for IgG subclasses. IgG1 and lgG4 were predominant subclasses deposited. No correlation of subclasses of IgG with clinical parameters were found.
  3,107 0 -
Lichen planus pemphigoides
A Ghosh, VN Vora, JN Dave, SV Shah, BJ Cardosco
January-February 1997, 63(1):68-68
  2,913 0 -
Pemphigus vulgaris with early eye involvement
Sanjay Rathi, Mary Jacob, Manoj Sethi
January-February 1997, 63(1):65-65
  2,883 0 -
Blister beetle dermatitis in West Bengal
Sujit Ranjan Sengupta, Koushik Lahiri
January-February 1997, 63(1):69-70
  2,149 0 -
Cetirizine induced urticaria
Puneet Bhargava, Seema Bhargava, CM Kuldeep, NK Mathur
January-February 1997, 63(1):71-72
  1,731 0 -
Linear scleroderma with bilateral lesions, contractures and kyphoscoliosis
JN Dave, SV Shah, A Ghosh, BJ Cardoso, R Goel
January-February 1997, 63(1):66-68
  1,661 0 -
Reactive perforating collagenosis
Adarsh Chopra, Shivali
January-February 1997, 63(1):70-70
  1,592 0 -
Leprosy and MDT: eradication vs cure
Gurmohan Singh
January-February 1997, 63(1):3-4
  1,578 0 -
Presidential address
Kalyan Banerjee
January-February 1997, 63(1):1-2
  1,446 0 -
HIV seropositivity in STD patients
Renu Jain, Sushil Chandra, Suman Sakhuja, Aseem Kumar, Manoj Verma, SK Arora
January-February 1997, 63(1):72-73
  1,426 0 -
Phenytoin hypersensitivity syndrome
SV Shah, NS Vora, JN Dave, R Goel, N Chakraborty, S Bhagat
January-February 1997, 63(1):68-69
  1,406 0 -
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