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   1995| March-April  | Volume 61 | Issue 2  
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Autologous miniature skin punch grafting in vitiligo
KG Singh, AK Bajaj
March-April 1995, 61(2):77-80
Forty-five sites of stable vitiligo in 32 patients refractory to medical treatment were subjected to autologous miniature skin punch grafting. Main instruments used were skin biopsy punches 1-3 mm in diameter. Donor sites selected were either gluteal region or extensor aspect of the thigh which were not affected by the disease in the past. Most of the grafts changed from brown to black and upper scales desquamated within 10-15 days. Uniform perigraft pigmentation was observed by 1-1 months and 90% area was covered within 3-4 months. The cases were followed up for six months. Fair to excellent results were observed in 87.5% of the cases.
  6,779 0 8
Managing recurrent genital herpes with acyclovir
TR Bedi
March-April 1995, 61(2):84-88
Seventy five patients of recurrent genital herpes (RGH) treated with oral or topical acyclovir and placebo were compared and followed for periods ranging 4 to 8 years in a prospective study. Oral acyclovir definitely helps RGH patients; it shortens healing time; postpones recurrences and instills confidence in the patients. There is sufficient evidence that RGH dies a natural death with time as seen after 8 years follow up in placebo group patients. Topical use of acyclovir cream is not as useful as believed.
  6,707 0 -
A comparative study of various therapeutic regimens in urticaria
Amiyakuamr Mukhopadhyay, S Nitin Vora, Jayend Dave
March-April 1995, 61(2):91-93
127 patients of urticaria were treated with chlorpheniramine maleate alone and in combination with cyproheptadine hydrochloride, ranitidine and doxepin and levamisole. Chlorpheniramine and doxepin combination showed a satisfactory result in 88.46% of patients. Overall study showed that a combination regimen is better than the antihistaminics alone. Drowsiness was the commonest side effect. Levamisole and chlorpheniramine maleate combination was found to be more effective than the antihimstamine alone.
  5,670 0 1
Dermatological manifestations of human immunodeficiency virus infected / acquired immunodeficiency syndrome patients in a referral hospital of Central Kerala
S Criton, KB Mohan, PU Asokan
March-April 1995, 61(2):89-90
A number of skin diseases are described in association with HIV infection/AIDS. In the present study the frequency of various skin manifestations among HIV infected / AIDS patients are noted. Generalised pruritus and dry skin were the common manifestations encountered. There was a significant absence of Kaposi's sarcoma, multi-dermatomal herpes zoster and oral hairy leukoplakia. A prominent hyperpigmented band on finger nails was seen.
  5,588 0 4
Chronic lymphocytic leukaemia manifestating as exfoliative dermatitis
R Dhir
March-April 1995, 61(2):102-103
A 60-year-old patient reported with a history of redness and peeling of the skin, and sensations of chills and tightness of the skin of three months duration. Clinical examination revealed exfoliative dermatitis, generalised lymphadenopathy and hepatosplenomegely. A peripheral smear showed features of chronic lymphocytic leukaemia.
  5,454 0 -
Study of exfoliative dermatitis
PR Bharatiya, PB Joshi
March-April 1995, 61(2):81-83
A study of 46 cases of exfoliative dermatitis revealed peak distribution in sixth decade and very high preponderance in males (M:F = 6.67 : 1). The highest single cause was found to be psoriasis (41.30%). Injudicious use of topical medicaments including herbal medicines and haphazard treatment were found to be the precipitating factors in 34% cases of pre-existing dermatoses. Laboratory investigations contributed little towards diagnosis except in lymphoma group; but were helpful in knowing systemic implications of the disease. Skin biopsy was found to be helpful in diagnosing underlying skin disorders in 18 cases (40.91%). Two cases (43.5%) had malignancy as the cause of exfoliative dermatitis.
  4,602 0 1
Multiple dermatofibromas with unusual features
Mohan Devinder Thappa, Sri Venkateswaran, Bha Garg
March-April 1995, 61(2):120-122
A 51-year-old-male with multiple dermatofibromas over both elbows and feet is reported for its rarity and unusual features
  4,412 0 -
Keratosis follicularis spinulosa decalvans
BSN Reddy, J Thadeus, BR Garg, C Rathnakar
March-April 1995, 61(2):106-108
The case findings in a 22-year-old male patient of keratosis follicularis spinulosa decalvans are described. In addition to the characteristic cutaneous, occular and histological features, he had striking angular stomatitis and fissuring of the tongue simulating vitamin B-complex deficiency. This is an unreported feature to our knowledge. The mode of inheritance suggested X-linked trait.
  4,378 0 -
Drug-induced pseudolymphoma syndrome
RR Mittal, C Jain, RLS Walia, Arun Chopra
March-April 1995, 61(2):94-95
Five cases of pseudolymphoma syndrome (PS) in children aged six to twelve years were observed after anticonvulsant drugs. In two cases PS was observed after ten days and in three after fifteen days of therapy with the offending drug. Three cases of PS were due to carbamazepine and had morbilliform rash and two cases due to phenobarbitone had erythroderma. All had fever, generalised lymphadenopathy and 4/5 had hepatosplenomegaly. Therapy with 15 mg prednisolone daily and withdrawal of the offending durg led to cure in 4/5 cases and one died due to congestive cardiac failure.
  4,218 0 -
Herpes zoster with ulnar nerve paresis
Adarsh Chopra, Mamta, Dimple
March-April 1995, 61(2):126-127
  4,102 0 -
Punctuate porokeratosis
A Ghorpade, C Ramanan
March-April 1995, 61(2):123-124
An 18 year-old-girl with multiple lesions of punctate porokeratosis on her right palm is described. The diagnosis was confirmed by histopathology. The disease has been reported rarely. Histopathology is important to distinguish it from other similar looking conditions.
  3,960 0 -
Generalised morphoea with lichen sclerosus et atrophicus and unusual bone changes
PVS Prasad, L Padmavathy, S Sethurajan, Pras Kumar
March-April 1995, 61(2):113-115
A 26-year-old male patient presented with multiple plaques on the limbs and trunk suggestive of morphoea. He also exhibited multiple, small, atrophic, hypopigmented macules on the left side of the trunk, the histopathology of which was consistent with lichen sclerosus et atrophicus (LSA). The patient developed large ulcers on the left leg and foot, and contractures with flexion deformity of the left ring and little fingers. This combination of generalised morphoea with LSA and unusual osteolytic bone changes is uncommon.
  3,764 0 -
Progressive symmetric erythokeratoderma
A Ghorpade, C Ramanan
March-April 1995, 61(2):116-117
Progressive symmetric erythrokeratoderma (PSEK, Gottron's Syndrome) in a 10 year-old-boy is reported. The diagnosis was confirmed by histopathology.
  3,752 0 -
Trichorhinophalangeal syndrome type 1
S Nitin Vora, Samir Shah, N Jayendra Dave, Mukhopa
March-April 1995, 61(2):111-112
  3,526 0 1
Pyoderma gangrenosum in childhood
ML Khatri, M Shafi, M Benghazil, A Machina, Sassi
March-April 1995, 61(2):96-98
We have treated 4 cases of pyoderma gangrenosum in infancy and childhood in past 2 years. The ages at onset were 6 months, 8 months, 6 months and 11.5 years respectively. Initial lesions were papulopustular in 3 and nodular in 1 patients but later on all of them developed ulcerative lesions with erythematous, violaceous, infiltrated or undermined edges. The lesions were numerous in 3 patients but few in 1 patient. The first patient had very high leucocyte count. In the second patient skin lesions of PG followed measles vaccinations. We could not reveal any association in the other two patients. None of the patient responded to antibiotic therapy. Three patients were treated successfully with dapsone and one with a combination of dapsone and prednisolone. We conclude that pyoderma gangrenosum is not so rare in infancy and it is more likely to occur without associated systemic diseases.
  3,182 0 2
Anaerobic peptostreptococcal positive case of hidradenitis suppurativa
D Flora Lobo, S Vatsala Rao, CV Raghuveer
March-April 1995, 61(2):127-128
  3,146 0 -
Basal cell carcinoma in a long standing case of lupus vulgaris
S Nitin Vora, N Jayendra Dave, Amiyak Mukhopadhyay
March-April 1995, 61(2):109-110
A case of a 67-year-old male patient with a longstanding lupus vulgaris developing basal cell carcinoma is reported.
  3,071 0 1
Sezary syndrome in a young woman
T Rajan Damodaran, T Sangeeta Amladi, Hem Jerajani
March-April 1995, 61(2):99-101
A young female patient suffered for 4 months from a widespread erythrodermic rash of unknown origin, marked by a peculiar hyperaesthesia. Haematological and biopsy findings were initially non-specific. A rapid deterioration, accompanied by infiltration of the skin, lymphadenopathy and hepatosplenomegaly was suggestive of Sezary syndrome, which was confirmed by finding of 40% of the lymphocytes being atypical (Sezary cells).
  3,069 0 -
Chronic lymphocytic leukaemia presenting as chronic generalised erythroderma
PVS Prasad, S Balasubramaniam, DC Arumainayagam, K
March-April 1995, 61(2):104-105
A 40-year-old lady presented with pyrexia of unknown origin and chronic generalised erythroderma. The blood picture was of leukaemia and the cutaneous histopathology showed leukaemic infiltration of the dermis.
  3,012 0 -
Tuberculosis verrucosa cutis of the scrotum
OP Singh
March-April 1995, 61(2):118-119
A 13-year-old boy had asymptomatic slowly progressive warty growth on the scrotum for 4 years. Examination revealed a 4 cm x 2 cm keratotic, nontender, indurated plaque on the right side of the scrotum. Histopathological examination of the lesion showed epithelioid cell granuloma with giant cells and lymphocytes in the dermis. Mantoux test was 15 mm x 20 mm. A diagnosis of tuberculosis verrucosa cutis of the scrotum was made. Six months of therapy with INH 150 mg and rifampicin 300 mg daily resulted in complete clearance of the lesion,
  2,524 0 1
Clinical profile of stds in HIV infected individuals
Shantanu Deo
March-April 1995, 61(2):125-126
  2,345 0 -
K Krishna
March-April 1995, 61(2):128-129
  2,298 0 -
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