The presence of cellular immunity against penile warts was examined by the tube leukocyte adherence inhibition (T-LAI) assay Peripheral blood leukocyte (PBL) from, six patients with penile warts--gave a positive reaction with the antigens prevaked from the whole extract of penile warts but not with the antigen prepared from normal penile skin. Adherence of PBL from normal donors did not differs significantly irrespective t)f whether the ant' ns, were from warts normal penile ago, skin. All 6 patients respon c we I to an antigenic extract of warts. LAI reactivity' diminished at the first month after removal of growth and gradually reappeared by the second month of removal and never declined till the third month follow up. This indicates some possible reason of recurrence of penile warts.

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A 7 year old girl had pseudo-ainhum, spina-bifida occulta, A hemivertebra and focal, neurogical deficit. The disease process was progressive for the last three years leading to amputation of the third digit and formation of constricting bands around -the fourth and the fifth digits of the left foot.

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A patient having contact dermatitis due to nickel on the wrist, sides of neck, thighs and legs, confirmed by patch tests with nickel sulphate, showed aggravation of the dermatitis following oral provocation with 25 mg nickel sulphate.

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A 21 years old male had hereditary benign intra- epithelial dyskeratosis. His mother and younger brother also were found to have the same disease. All the three had oral and conjunctival lesions. The histopathological features were characteristic.

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A comparative evaluation of 2 regimens of multidrug therapy ( IAL modification and the original W'HO regimen) in multibacillary leprosy is presented. Patients were given MDT till the point of clinical and bacteriological inactivity. It was found that the IAL regimen confers a statistically significant advantage in patients with a. hi er initial BI (more than 2), as far as bacteriological inactivity is concerned. In patients with a lower initial BI, both regimens were equally effective. Side effects and lepra reactions were within reasonable limits with both the regimens, We feel that the LAL modification of the WHO regimen should be used in multibacillary leprosy, especially in cases with a high initial Bl. The higher Proportion of cases rendered negative- compensates the slight increase in the cost

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A 17-year-old boy had bathing trunk nevus with multiple large neurofibromata on the nevus and raised intracranial tension presenting with bilateral papilloedema and pyramidal tract sings. This combination, of features is extremely rare.

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Primary inoculation tuberculosis in two children confined to the face was seen over a period of six months the first case was an eleven year old boy with a painless non-healing ulcerative nodule over the left ala nasi with matted' non-tender submandibular lymphadenopath-y of 2 months duration. Mantoux test and biopsies of the lesion and the lymph node helped in the diagnosis. The second child was a six-year-old boy with a painless ulcerative lesion over the left cheek of 5 weeks duration. The left submandibular group of lymph nodes were enlarged, non-tender and matted. Aspiration cytology showed eptihelioid cells, lymphocytes, polymorphs and eosinophils. Mantoux test negative initially became positive by 2 months. The lesion started subsiding with antitubercular treatment in both the cases.

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Analysis of the clinical and laboratory data from 21 patents of cutaneous tuberculosis seen over a period of 10 years revealed that it is rare in eastern Libya. There were 15 males and 6 females. Lupus vulgaris was seen in 11, scrofuloderma in 4. Three patients each had tuberculosis verrucosa cutis and papulonecrotic tuberculid. The diagnosis in each case was confirmed histopathologically.

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Multiple lesions of psoriasis circumscribed to the hypopigmented patches of incontinetia pigmenti achromains were observed in a male child.

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The patients who attended the STD clinic of our hospital during the last 10 years were studied retrospectively to work out the pattern of major sexually transmitted diseases viz. -syphilis, ionorrhoea, chancroid, lymphogranuloma vencreum and donovinosis. The total number of patients was 1093, The relative incidence of chancroid was found. higher (37.78%) than syphilis (32.47%), gonorrhoea (24 79%) mixed infections (3.38%), donovanosis (1.18%) and lymphogranuloma venereum (0.36%).

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A 45 year old female had grouped pruritic Papules and vesicles with a few scattered tensebullae, symetrically distributed on the extensor surfaces of limbs, back and buttocks. Nikolsky's sign' was negative. Histopathology revealed intra-epidermal suprabasal cleft along with acantholysis. Eosinophilic spongiosis was also present. The patient recovered with dapsone.

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A middle aged female with frequent attacks of non- inflammatory purpura was confirmed to have systemic lupus erythematosus. coagulation profile was-normal.

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In a family of four children, all females, three sisters presented with Clouston's disease or hidrotic ectodermal dysplasia. The case is reported for the rarity of presentation in a single generation with no history of other family members affected.

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