One hundred consecutive patients suspected to have contact dermatitis due to topical medicaments were patch tested with 20% neomycin, framycetin, gentamicin as well as other commercially available antibacterial agents. Neomycin sensitivity was observed in 16.0% cases, while framycetin and gentamicin sensitivity was seen in 11.0% and 4.2% respectively. Fifty percent neomycin hypersensitive cases cross - reacted with framycetin and 22.00/o cross reactivity was observed with getamicin.

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Two patients aged 12 and 16 years, developed severe dermatitis on their face and hands with oedema and hyperpigmentation following contact with the marking nut. Patch tests with the marking nut produced a buila with hyperpigmentation in both the patients, as also in all the 5 normal unexposed controls. Marking nut is considered to be a storng irritant.

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In a comparative study, 60 patients of psoriasis vulgaris were subjected to PUVASOL and PUVASOL with trimcinolone acetonide in two different groups of 30 patients each. Patients given photochemotherapy with 8 MOP and local application of trimacinolone acetonide showed marked imorovement (66.6% and 60%) after 4 and 8 weeks of therapy in comparison to 26.6% and 16.6% in the group where no topical corticosteroids were applied. None of the patients showed any adverse reaction to the treatment.

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DiflucortolonevalerateO.1percentand hydrocortisone acetate 1.0 percent were compared in a randomized double blind contralateral, intra individual trial in fifty-two patients. Duration of treatment was three weeks. Both the drugs showed significant response after the first second and the third weeks of treatment. At all periods the reduction in pre-treatment signs and symptoms was greater for diflucortolone as compared to hydrocortisone. Response to therapy in eczema was very good in 89.1 percent cases and good 10.9 per cent. Patients having psoriasis and chronic DIE showed very good response in 33.3 per cent and good in 66.6 per cent cases. There were no side effects.

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A 33 year old male had a s increasing hard nodule on the lower part of the scortal skin, for the last 10 years. Histopathology revealed calcified masses without any ifflammatory recction.

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A 55 year old male having adenocarcinoma of the caecum developed photosensitivity and temporary nail pigmentation following use of systemic 5 fluorouracil. The lesions disappeared following withdrawal of the drug, but recurred when the drug was started again.

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A 50-year-old man had dyschromatosis universalis hereditaria manifesting as asymptomatic macular pigmentation and depigmentation present all over the body almost since birth. There was no atrophy or telangiectasis. In addition, the patient had associated features of solar elastotic syndrome.

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A 65 years old male developed nevoid basal cell carcinoma syndrome, manifesting as multiple basal cell epitheliomas, marked mutilation of the face and characteristic pitting on the palms and soles. Calcification of the falx cerebri and scoliosis of the lumbar spine were also seen.

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Squamous cell carcinoma developing in a plaque of chronic discoid lupus erythematous is reported in an elderly male.

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Unilateral -Darier's disease was observed in an adult male involving one half of the body.

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Six hundred and fifty seven cases suspected to have contact dermatitis reporting at 14 dermatological centres of armed forces hospitals during a 12-month period were investigated. One hundred sixty one cases Showed positive patch tests. Sixty-five cases showed positive patch tests with footwear materials including rubber, leather and canvas. Clothing, topical medicaments, airborne allergens and marking ink were responsible in 5.75%, 25%, 3.82% and 0.85% patients respectively.

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Two industrial selling agents based on methyl methacrylate were evaluated for their allergenic potential. Clinical examination of the 20 employees of the firm exposed to the agents for 1 month to 5 years did not reveal any evidence of contact dermatitis. Patch tests with the sealing agents on 56 volunteers including 12 employees were also negative in all.

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A case of bilateral nevus fuscocaeruleus ophthalmomaxillaris with fluctuation in the intensity of colour during each menstrual cycle is reported. It is not described earlier in the literature.

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A 29 year old male developed dermatitis on the adjoining surfaces of the right index and the middle fingers, the site for holding cigarette/ bidi. Patch test with the tobacco of the bidi was positive.

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