Thirtycasesof vitiligo eachwithminimum of two lesions undent replacement graft and multiple punch grafts in one lesion each. Complications observed at the recipient site like infection and raised nigosed surface were significantly more in replacement grafts. Hypopigmentation of the graft was significantly more when the disease was progressive.

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Twenty uncomplicated cases of psoriasis and an equal number of matched controls were evaluated using the oral and steroid primed glucose tolerance test. Six of the twenty psoriatics (30%) studied showed an abnormal glucose tolerancewhereas only one of the twenty control subjects (5 %) showed abnormality (p < 0.05). A relationship was found between abnormal glucose tolerance and surface area involved by psoriasis.

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Two cases of terminal phalangeal erosion by subungual warts are described. Demineralisation of bone has been reported previously due to many other pressure producing lesions but rarely due to viral warts. Remineration did not occur upto six months following treatment.

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A case of Apert's syndrome in a one year old female child is described and literature reviewed. She was the first born of a young couple. She had congenital syndactyl of toes and fingers, acro-cephalic skull, flat facies, exophthalmos, hypertelorism and greasy skin. In addition to the typical radiological features of this syndrome which the patient showed, thickened first metacarpals forked at the base were also seen. There were two phalanges for each toe. Calcification was seen intracranially. These radiological features have not been mentioned so far in the literature reviewed.

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A caw of "Lumpy Mycetoma" (subcutaneous phycomycosis) proved clinically and histopathologically and occurring on the scalp is herewith presented because of rarity in site of involvement and incidence. Advantage of using the term "Lumpy Mycetoma" is discussed

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A case report of disseminated cutaneous cryptococcosis with Hodgkin's disease is presented. No foci in the lungs, central nervous system, bones, gastro-intestinal tract, liver, kidneys or heart were detected. C.neoformans was cultured, identified by its capsule, growth at 37'C ability to produce urease, specific nitrate and sugar assimilation and pathogenicity for the mouse. Histo-pathologically the organism was demonstrated in the tissue sections. Clinical subsidence was seen with amphotericin B 0.5 mg/kg. for 22 days. The fact that present day use of steroids, immuno-suppressives and anti-neoplastic agents are known to predispose to this infection is emphasised.

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A rare case of generalised morphea with extensive calcification in a female patient is reported. The literature on the same is briefly reviewed.

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A rare case of porphyria cutanea tarda symptomatic&, in a 20 years old muslim female patient, treated successfully with phlebotomy, exchange transfusion and tablet periactin is described.

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Reiter's syndrome consists of urethritis, conjunctivitis and arthritis with a wide variety of manifestations and sequelae. Urethritis and conjunctivitis may be so mild and of such duration that they are forgotten by de patients. In this report we describe a case with persistent conjunctivitis refractory to a short course of systemic corticosteroids as well as local stmid ointment.

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In a double blind paired comparison study, the patients with steroid responsive dermatoses received desoxymethasone 0.25% on lesions on both sides of the body for first 4 days and desoxymethasone 0.25% on one side and 0.05% on the other side for the next 10 days. There was no significant difference in the percent reduction in severity scores of symptoms in global assessment or patient preference between the two treatments.

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A fluorinated topical corticosteroid ointment, Esperson 0.05% was compared with a placebo in a randomised double blind right left trial in 52 patients having different dermatoses for a period of 7 days. It was found to be effective and produced no side effects.

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