Fifty cases of allergic contact dermatitis from Parthenium hysterophorus have been studied in detail. Clinico-epidemiological features have been described. Patients present with any of the four observed patterns of dermatitis viz. atopic, photosensitivity, seborrhoeic and miscellaneous. Patients were patch tested with 12 extracts of the plants in six solvents producing differing reaction. Limited chemical analysis of the plant extracts yielded various fractions of which three were found to be immunologically active. Chemical nature of parthenin which is a known allergen of this plant has been studied. Possibility of cross sensitivity with other plants is briefed.

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The relative efficacy of two commercially available anti-dandruff shampoos, one containing selenium sulfide and the other containing an antiseptic, was studied in 40 cases both subjectively and objectively. Shampoo containing selenium sulfide was effective in 72.5% of the cases while the shampoo containing, antiseptic was effective in 47.5% of the cases. Patient compliance was 57.5% for the former and 12.5% for the latter. In 30% of patients either of the shampoo failed to show much improvement. Both the shampoos showed negligible side effects.

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A case of nocardial mycetoma is presented occurring at upper back. Clinical and laboratory studies established the diagnosis. Excellent therapeutic response was obtained with sulphadiazine alone within five months of therapy.

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A case of Klippel - Trenaunay - Weber syndrome in a 13 years old male with involvement of three extremities is reported. A brief review of literature is given.

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Cauterization type of reaction to patch tests with fresh garlic juice was seen with almost the same frequency (60%, 52% and 50% respectively), in the patients having contact dermatitis due to vegetables, controls who were routinely exposed to raw garlic, and another group of controls not exposed to garlic. The papulovesicular reaction on the other hand was seen in 70% of the patients, 22% of the exposed controls and 8% of the unexposed controls. It was concluded that the cauterization reaction does not show any correlation with the state of contact hypersensitivity and should therefore be ingnored.

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Out of 365 patients, who attended S T D clinic of Lok Nayak J P Hospital, New Delhi during the period July 1975 to November 1977, 126 (3.5 percent) were suffering from donovanosis. 84 percent of the patients with the disease were aged between 20 and 40 years. Majority of the patients (92.9%) had lesions on genitalia while inguinal regions were involved in 12.7% only. Increasing magnitude of the disease in Delhi and surrounding states of North India is highlighted.

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Six cases of p-,oriatic arthritis are presented with clinical, laboratory and radiological features and review of literature. Four out of six cases are 'distal arthrits' and two cases are arthritis mufilans of long duration. All our cases are males and hence no case of rheumatoid variety, which is common in females, is being reported. The aim of this paper is to represent all the parameters for this study of psoriatic arthritis namely clinical, laboratory and radiological features, which are not well documented in Indian literature.

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Treatment of 64 patients having urticaria of unknown aetiology with antibacterial drugs for I to 2 weeks brought relief in 27. Out of the remaining 37 patients, 6 obtained relief on receiving a second different antibacterial drugs. In a control group of 18 patients having w-ticaria of known aeti6logy, none obtained any relief with antibacterial agents. A double blind comparison between tetracycline and a placebo in another group of 18 patients having urticaria of unknown aetiology showed tetracycline to be superior. It seems worthwhile trying a course of antibacterial agents in patients having urticaria of unknown aetiology.

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A rare case of gummatous syphilis of the scalp involving underlying bones in a 50 years old male is reported. The diagnosis was confirme,d by history, clinical examination, serological and radiological findings. Salient radiological features regarding gummatous osteitis are described.

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A case of Reiter's syndrome occurring in a young mate aged 20 years having extensive skin lesions of keratoderina blenoffhagica is presented along with a review of literature. Although urethritis was absent, other clinical and histopathological features of the cutaneous lesions led us to the diagnosis. The-possible relationship of postural psoriasis to Reiter's syndrome is discussed. Failure of the patient to respond satisfactorily to steroids, antibiotics etc, prompted the use of rnethotrexate in the case. The result was dramatic, as the patient completely recovered within ten days of starting treatment.

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Haematologic condition producing leg ulcers are very common except in hemoglobin S homozygous state. Thalassaemia group of disease causing leg ulcer is thus considered to be rare. A case of hemoglobin E thalassaemia with leg ulcer is presented in this article.

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A case of Rothmund-Thomson syndrome in an 8-year-old Indian male is reported. The patient had bilaterally symmertrical superficial pigmentary deposition of thin nebulae in the lower one-third of the cornea and oonjunctiva. Urinary togmphy rcvmw a dibasic aininoacid with excretion of arginine, lysine;.hmncicystine and glycine. Other features of interest in this patient were onset at the age of 8 days and start of the disease on the hands and feet rather than face. The patient also developed repeated ulcerations on the hands and feet subsequent to minor trauma.

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