Thirty- one cases suffering from various dermatoses comprising bilateral symmetrical single lesions were treated with topical application of flumethasone pivalate (Locacorten cream) with neomycin on one side and hydrocortisone with neomycin ointment on the other side and the result evaluated. Flumethasone pivalate with neomycin elicited a better response compared to hydrocortisone with neomycin ointment.

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Two cases of lepra reaction precipitated by filariasis are reported. The treatment of filarisis with diethyl carbamazine citrate could effectively treat the reaction without any recurrence. The necessity of recognising filariasis as precipitating factor for lepra reaction in tropical countries where the filariasis and leprosy may both co-exist in high proportions is emphasized. Proper investigation for diagnosis and treatment of filariasis in such cases shall have rewarding results

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Fourteen patients of granuloma vencreum sponded to chloramphenicol therapy by mouth. The amount of chloramphenicol administered varied from 14 to 64 grams with an average of 42 grams. No side effects were observed. Inspite of good response and absence of side effects it is suggested that the use of chloramphenicol in this disease should be restricted to patients not responding to other antibiotics to guard against the major complications of chloramphenicol therapy.

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A 5-month-old child was brought to Skin Department with multiple papular lesions of few weeks duration. The first lesion was seen on back at the age of three months, which subsided, by itself in 3-4 weeks. Later on similar lesions developedon back, frontof chest,arms andlegs. The papules were oval, 0.2 to 1.5 cm diameter, yellowish colour and were quite firm on palpatation. They were non-itchy and were distributed discretely over back, neck, trunk and extremities. They persisted for 4-6 weeks and then subsided by themselves leaving dark pigmented atrophic area. Skin elsewhere was normal. Systemic examination did not show any enlargement of liver or spleen. Heart and lungs were normal. Mucous membrane and eyes did not show any abnormality.

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Ten cases of bullous drugs eruptions due to salicylates and sulphonamides were examined immunoclectrophoretically. Serum total protein was within normal limits Bullous fluid protein was markedly diminished. Sera of patients of bullous drug eruption due to salicylates showed absence of IgG in one case, IgA in another case and IgM in three cases. On the other hand sera of patients of bullous drug eruption due to sulphonamides showed absence of IgM in two cases and its decrease in three cases. The fluid of salicylates bullous drug eruption shoa,ed absence of IgG in one case and IgA in another case. There was also decrease of IgA in one case and decrease of IgM in two cases. The bullous fluid of sulphonamide drug eruption showed absence of IgA in one case and IgM in two cases. Other abnormalities are mentioned.

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A 25 years old male, farmer by occupation, had thick, hyperkeratotic, heavily crusted lesions, discrete and disseminated over the extremities, face and trunk. Crusts were easily detachable exposing highly vascularized raw areas. There were scar marks also. Inguinal lymph nodes were enlarged. Culture yielded Nonnodendrum pedrosoi. The patient had 42% eosinophils. A good therapeutic response was achieved with iodides.

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The author reports a 35-year-old male with multiple ulcers of 6 months duration. There were eight ulcers 1-10 cm in size with irregular, ragged blusish-red edges and the base covered with yellowish slough which when removed, there was profuse bleeding. There were a few pustules at the margin. Patient responded to tetracycline and prednisolone therapy.

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