In the above series there were 5 cases of herpes zoster with severe neuralgic pain and active skin lesions and all were past 45 years of age. These patients were most likely to develop post herpetic neuralgia as a complication. When these five cases were given paravertebral X-ray therapy, the pain was promptly controlled and none developed post herpetic neuralgia. In the single case who had already developed post herpetic neuralgia X-ray therapy produced partial relief from pain and required corticosteroids for further relief. These findings suggest that paravertebral X-ray therapy is useful in preventing post herpetic neuralgia and may also help in relieving/reducing pain in cases where this complication had already developed.

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Minocycline, 7-dimethylamini - 6 deoxy 6 - demethyltetracycline, &new semi-synthetic dervative of tetracycline was given in 50 cases of pyogenic infections of the skin of acute and chronic nature. The dosage of minocycline used was a loading dose of 200 mg in the morning and I 00 mg. the same evening, followed by I 00 mg twiccdaily for6 to I I days. In several cases, 100 mg of minocycline was later given once daily for periods varying from 2 to 23 days. The causative organism in most of the lesions was staphylococcus aureus. In 24 cases, these organisms were resistant to tetracycline and in 36 cases, to penicilun. None of the organisms were resistant to minocycline. Results were judged as excellent in 3 cases, good in 22, fair in 22 and poor in 3 cases. Minor side effects like giddiness were noted in 3 patients, nausea and vomiting occurred in another patient despite these side effects the patients continued the course of minocycline.

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The total number of cases of donovanosis from various clinics in India were collected for the year 1969. The data thus collected were analysed based on the influence of climatic conditions on the prevalence of this disease. The results suggest that a high constant temperature of 75-90 degree F and moderate relative humidity of 50-60% with moderate rainfall are favourable conditions for endemic foci of donovanosis. Racial factors seem to be unimportant. A minor prevalence of donovanosis in Madhya Pradesh and Jammu & Kashmir is expected.

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A man aged 40 years Ramaswamy, was admitted with a history of red rashes and blisters all over the body. Four days prior to that he had taken pills for headache - 4 tablets of Aspirin 5 grain each as one single does as the headache was severe. He had similar attacks previously when he had taken aspirin.

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The case of 20 years old male with Papillon - Lefevre syndrome is reported. The patient had lost all the teeth at the age of 17 years and there was no evidence of any developing tooth -on radiological examination. Cytogenetic study of bone-marrow showed a normal karyotype without any numerical or structural abnormality of chromosomes.

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Four patients of syphilitic perforation of the palate have been rehabilitated by a simple dental prosthesis - the dental plate. The follow up of these cases shows uneventful and satisfactory course. The relative merits and demerits of this procedure are discussed in comparison to surgical procedure.

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A family with seven patients of trichoepithelioma is presented. The mode of inheritance is shown to be autosomal dominant.

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