A case of onychomadesis affecting the nails of all fingers and big toes is reported. The patient also had keratosis pilaris like eruptions on the body and severe acneiform eruptions on the face, symblepheron and pseudo-conjunctival cysts in the eyes. All these occurred as sequelae of exfoliative dermatitis due to penicillin allergy.

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The frequency of incidence of the so called biologic false positive reactions for syphilis in leprosy, specially investigated with a battery of currently used standard serologic tests for syphilis using non-specific tissue extract antigen and controlled by the known specific TPI test for syphilis using specific treponemal antigen at Madras is presented. It is confirmed that all the currently used STS produces BFP reactions for syphilis in leprosy in the absence of a simultaneous treponemal infection. However, the frequency of BFP reaction with standard test for syphilis obtained in leprosy in this study at Madras has been found to be far less than those reported earlier by other investigators in this field in North India and abroad. A significant proportion of the leprosy patients at Madras who were found reactive to the current standard tests were found to have simultaneous latent treponemal infection. The comparatively higher figures reported by others is considered to be due to the fact that a possible simultaneous treponemal infection in leprosy patients could not be easily excluded by them clinically alone, in the lack of the specific TPI test for syphilis. The various aspects of this problem are discussed.

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A case of chronic granulomatous suppurative lesion of foot is reported. Smear examination, culture of pus and histology revealed the diagnosis of actinomycosis. Causative fungus was actinomyces bovis. No improvement was noticed by medical treatment. Patient was cured of the condition by excision of the affected part and a skin graft.

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The analysis of the results of 35145 Serological Tests for syphilis done in the Laboratory of the VD Training Centre, Safdarjang Hospital at New Delhi during 1958-61 was made bringing out the following findings: A sero-reactivity rate of 6.1 % to all tests and 7.2 % as partial reactors (reactive or doubtful in any) in the total sera have been observed. 22.8 % sera were reactive from the sera received from the VD Training Centre of the Safdarjang Hospital. A reactive rate of 8.5 % was observed among the patients referred from Hospitals in New Delhi. 5.5 % sera were found to be reactive from the people referred by CGHS Dispensaries. The ante-natal sero reactivity rate was 2.6 %. Of the three tests; VDRL is the most sensitive, Kahn is the least sensitive and Meinicke in between the two.

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Two cases of post-treatment gonorrhoea are reported, who did not respond to PAM 1.2 mega units but improved dramatically with heavy doses of crystalline penicillin.

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