The following conclusions have been made by the study of 53 cases -

In this paper an attempt is made to estimate the burden of venereal diseases in India. Since these are not notifiable in India, and also the data currently available are inadequate for cost - benefit analysis, the estimates computed are preliminary and, therefore, to be considered minimal. The estimation procedures involved the application of results from studies on the prognosis of untreated syphilis in Norway and the United States of America, review of litrature on the incidence of syphilis in India and the computation of direct and indirect burden due to neurosyphilis, congenital syphilis, gonnoffhoea, chancroid and other VD. The liability due to syphilisand gonorrhoeais estimated to bers. 17 crores and Rs. 15 crores, respectively. The persons involved for these were 13 million and 26 million, respectively. Th6 burden due to neurosyphilis was Rs. 22.4 million as against Rs. 41 million for cardiovascular syphilis

A case of porokeratosis is described with formation of cutaneous homs, The condition began in a male at the age of 20 years. All the cutaneous homs occurred only on both the lower limbs.

On examination the patient was moderately built and moderately nourished. He had paralytic squint in his left eye. Examination of skin showed multiple thin scars and pigmented macules on face, back or trunk and extremities. There were few crusted lesions on the fingers. Face had typical withered and "monkey like" appearance. On the legs there were some crusted lesion. Mucous membranes, nails and teeth were normal. Hypertrichosis was notable on face and limbs. Urine and stool were positive for porphyrins.

A case report of spina bifida occulta with hypertrichosis in lumbosacral region and unilateral lesions in the left lower extremity is presented. The last two phalanges of the left 4th toe were absent, the left little toe appeared shorter. -The nails of the left 2nd, 3rd and the 5th toes had almost disappeared. Distal third of the left foot showed anaesthesia on both the plantar and the -dorsal aspects. The vertebral column had a scoli-osis towards right in mid thoracic region. The left lower extremity appear toasted more so below the knee. The ankle ierk was absent on the left side. Left plantar jerk could not be elicited. X-ray lumbar spine revealed spinal bifida L 4, .irregular devel , t of L5, SI hemivertebra with no ossification on the right side.

Seventeen cases of various types of atopic dermatitis were treated by topical application of an ointment containing demeclocycline and triamcinolone acetonide in a lanolin and white petrolatum base. Results were assessed clinically, subjectively and histologically (biopsy specimens). All patients improved; in 10 of the 17 patients, the clinical improvement was over 75 percent. The ointment had a remarkable antipruritic effect which was evident on the fourth day of treatment. No untoward effects were noticed.

A 50 years old male had swelling in the left groin of eight years duration. The swelling got ulcerated and became painful for the past 15 days. 'Mere was a similar swelling over the sterior aspect of left thigh about 20 years ago. PO It was removed and the operated area healed well. The clinical examination revealed the presence of an irregular lobulated swelling 6 inches by 4 inches in the region of left groin. The skin over the swelling was tethered and at one area it got ulcerated. Each lobule was about the size of a lime, firm in consistency andessentially adherent to each other with few discrete ones. The whole mass was freely mobile over the deeper structures. There was a solitary, isolated circumscribed swelling (2 inches in diameter) over the medial aspect of left thigh. The skin was tethered to the swelling which was firm and freely mobile. Histopathological appearances were suggestive of syringoma, arising from the apocrine gland structures.