A total of 692 heterosexual males which included 130 men with non-gonoccal urethritis (NGU) and 562 age-matched controls, were studied. Mycoplasmas were cultivated in liquid PPLO medium tubes containing arionine and urea. Mycoplasmas were isolated in 24 (18.59o) of the 130 patients and 76 (13.60/o) of the 562 controls. Ureaplasma urealyticum was isolated in 18 (13.9%) gatients with NGU and in 21 (3.8%) controls. Mycoplasma hominiq was isolated in 6 (4.6%) patientuft NGU and in 55 (9.8%) controls. Ureaplasma urealyticurm has a definite in NGU.

Seventy four patients having acne vulgaris were treated with 0.05% retinoic acid (23 patients) 2% erythromycin lotion (23 patients) or rectified spirit (28 patients), used

Levamisole, a wide spectrum antihelminthic has been compared for its, curative effect on condylomata acuminata with podophyhin when given alone or combind with podophylfin topically. A cure rate of83.6% was obtained with podophyllin alone after in average Of 1.6 applications. With combined therapy, comparable good, results- were. Obtained i.e. a cure rate of 79.0% after applications. Levamisole was found to tie completely disappointing and had no effect on warts either given alone or in combination with podophyllin. No serious local or system side effects were noted with podophyllin and levamisole. Perianal and intraameatal warts were found to be relatively resistant to therapy.

This study was carried out to determine whether an abnormality in polymorphonuclear leucocyte (PMN) function and/or a deficiency in immunoglobulins (IgG and IgM) and complement (C4 and C3) could be the underlying cause of chronicity in DCPA. Twenty adult males were studied. Penicillin resistant coagulase positive S. Aureus was isolated from the pus samples of all the patients. AU the strains were susceptible to chloramphenicol, cotrimoxazole anderythromycin. Patch and usage tests done with coconut and mustard oil were negative. The total and differential leucocyte counts in all the patients were within normal limits. In vitro PMN functions were estimated by measuring percentage phagocytosis and intra cellular killing capacity (ICK) using S. aureus as the test organism. Both these parameters were significantly raised before treatment (p.001) and returned to normal after treatment. Immunolobulin levels did not rise above normal which may suggest a depressed response to bacterial infection. Complement (C3) levels were significantly lower (p) than the controls.

One hundred patients suffering from various allergic disorders due to inhalants were advised to u soft nasal filters. They included 46 patients of urticaria, 44 patients of bronchial asthma and 10 patients of allergic rhinitis. The response was excellent in 47%, good in 32% and poor in 21% cases. The acceptance rate was 80%. The main reasons. for non-acceptance, were foreign body sensation, increased nasal secretions and cosmetic problem, The main drawback in soft nasal filters was their short life because these did not last for more than, six months even when used under standard conditions.

Three Libyan patients with epidermolysis bullosa acquisita (EBA) had adult onset of the disease with tense vesiculo-bullous lesions on the sites of pressure and trauma, healing with atrophic scars and milia formation. None of the patients had family history of epidermolysis bullosa. The 'diagnosis was based on clinical and histopathogical features snowing subepidermal bullae, and exclusion of other vesiculo-burous disease. In addition, the diagnosis in case I was confirmed by direct immunofluorescence studies showing linear deposits of IgS and C3 at the basement membrane zone. Case 2 was already having systemic lupus erythematosus for the last 3 years when she developed EBA. Case 3 was having anemia, leucopenia, raised ESR and gamma globulin. Thus, association of SLE was suspected in this case too although the diagnosis could not be confirmed.

A 25 year old female with xeroderma pigmentosum since 3 ye4ws of age, developed a nodular growth on the left ala of the nose since 4 months. Histopathology revealed m ant melanoma of the nodular variety. A squamous cell carcinoma was also detected at the fimbus in the right eye. There were no metastases.

In a patient with extensive, bilateral fixed drug eruption the offending drug was confirmed by provocation to be oxyphenbutazone with a cross reactivity with phenylbutazone.

A 55 year old male had papulo-nodular and plaque type lesions on upper eyelids, chest, neck and extremities. He hadjoint pains and abnormal lipid profile. The histiopathology showed typical picture of reticulohistiocytosis.

A 65 year old, immunocompetent, male patient developed herpes zoster ophthalmicus associated with a generalized varicellifform euption and meningo-encephalitis. Meningo-encephalitis was diagnosed on the basis of CSF picture. The patient responded in seven clays to oral acyclovir (400 mg five times a day)

TWO brothers aged 9 and 7 years had asymptomatic, umbilicated papules on their extremities, buttocks and hair-lin , since infancy. The lesions would heal spontaneously with atrophic scarring, but new lesions would keep appearing especially after trauma. Koebner phenomenon was observed on several body sites. Histopathology including Van-Geison's stain confirmed the lesions to be reactive perforating collagenosis. There was no evidence of diabetes, renal or heapatic disease.

A 26 year old female developed laxity and wrinkling of the skin of both the upper eyelids for the last 5 years. This was preceded by 4 attacks of lid edema starting at the age of 16 years.

Two- patients had Melkersson-Rosenthal' syndrome. One of them had all the 3 components of the syndrome-facial paralysis, plicated tongue and macrocheilia, while the other had only 2 components-macrocheilia and plicated tongue. Oral antihistamine therapy for 3 weeks was ineffective in. both cases. But appreciable clinical response occurred after clofazimine therapy in both cases.

Thermal sensory thresholds of 85 healthy subjects with aormal height to weight range, and classified into five age groups between 10 to 60 years were measured and analysed statistically. Measurements were carried out with an electronic device at two 'different sites; forehead (FH) and finger-tip (Fr), almost at constant (28-32C) ambient temperature and rel.,i(ive humidity (00- 65%). Since no significant sex difference was observed in any.,igc group at either.,,iie, data for both sexes %k,cre pooled to comliute the groupmeans.Thc agegroul)sshowed different mean thermal sensory threshold levels which progressively increased with age at both the sites. The analysis of variance among the groups was found to be significant at 1% for both FH and FT. While the data in groups 1 to 3 were relatively homogenous, greater variability was found in groups 4 and 5. The threshold level, y, and the age group mean, x, could be related by an empirical equation y = A + B in x, where A = 30.85 for FH and 27.82 for Fr and B = 1.37 for FH and 3.39 for FT.

Augmentin (Amoxycillin 3 . gm combined with 250 mg clavulanic acid) and ampicillin 3.5 gin and I gm probenecid orally were evaluated in 50 patients for treatment of uncomplicated gonorrhoea. Success rates of 80% and 100% were obtained with augmentin and ampicillin with probenecid respectively in non-PPNG strains. None of 4 PPNG strains responded to ampicillin-probnecid. Augmentin in single oral dose cannot be recommended for the treatment of non-PPNG strains in India.