Five, cases of cutaneous metastases from bronchogenic car are reported for their rartty and clinical interest. In 3 cases the histopathology showed an adenocarcinomatous deposit; in the remaining 2 cases, the histopathology showed a squamous cell carcinomatous deposit. Only 1 of the 5 patients was a female.

Seventy five paraplegics under institutional care, were followed up for one year to study the incidence and pattern of skin diseases, Factors such as immobility, amitosis, vasomotor instability and sensory loss made the skin of, the paraplegic part vulnerable to diseases. A high incense of intertrigo of the feet mostly bacterial was wen, but the incidence of fungal, bacterial and viral infection elsewhere was not higher. Dryness

A 35 year old male having erythematous and verrucous plaques and scars on his right lower limb, diagnosed as a case of chromoblastomycosis is described. The importance of close scrutiny of lesions for brownish- black dots and their direct microscopic exarmination in 10% KOH for the causative fungus is highlighted. The causative fungus was identified as Cladosporium carrionni.

To study if psoriasis has any association with atopy, history of atopy in the patients and his relatives was elicited in 356 unselected cases of psoriasis and, comared with 1000 randomly collected patients- having other diseases. The study showed a negative and the personal history of atopy.

A 29-year-old male developed dermatofibrosarcoma protuberans over the thigh. It was large, multi-nodular and asymptomatic.

Tinea nigra in the axillar-y region of a south Indian youth is reported. A KOH mount of the scrapings showed typical fungal elements and the culture yielded Exophiala Werneckii.

A 67-year-old male having oesophageal carcinoma had several discrete firms to hard cutaneous nodules distributed all over the body. Biopsy confirmed these nodules to be metastatic deposits from the oesophageal carcinoma.

A case of urticaria pigmentosa with bullous lesions in a 2-year-old mile is presented. No systemic manifestation of mastocytosis was found.

A young man developed multiple, bilatera depigmented, vitihgoid macules on .his palm and soles. along with roseolar rashes on the trunk and generalize I as a anife tation of Ymthadenopathy secondary syphilis. There was no associated melanoderma. Blood VDRL was positive 1: 128 and histopathology was suggestive. AU the manifestations disappeared following treatment with penicillin.

An unusual case of fixed drug eruption with a symmetrical distribution on the hands and feets is reported.

Anaphylactic reaction (type I hypersensitivity) following Mantoux test with purified protein derivative was observed in a 17 year old girl, who had no evidence tuberculosis in her. Repeated injections of the test antigen produced more and more severe hypersensitivity reactions.

A case of anaphylactoid-reaction following tetanus toxoid injection is reported.

An adult female who developed plica neuropathica following prolonged mental

A 50-year-old man developed two giant cutaneous horns measuring 4 cm and 1 cm respectively on his right palm.

A 26 year old man developed a locally recurrent tumour on the back. The lesion

To study the effect of prothionamide. on the infectivity of untreated lepromatous patients 20 cases were randomly given either 250 mg or 500 mg prothionamide monotherapy daily for 2 months. All patients tolerated the drug well. Clinical improvement with healing of mucosal ulcers was seen in 13 of the 16 cases. Nasal smears become negative in all the cases within 2 months. Mouse footpad inoculation done from biopsy specimens/skin scrape suspension- s became non infective to mice in all the cases within the trial period. There was a substantial reduction in ,the MI and histopathology showed complete fragmentation of the bacilli with a significant increase in the lymphocyte content. The -findings suggest a rapid bactericidal effect and a similar, use fullness on both the doses of the drug for the treatment of multibacillary leprosy.