It is now well recognized that a considerable proportion of urethritis is not due to gonococcus (NGU), but due to various other causes viz. 1) bacterial infection 2) virus infection 3) protozoal 4) mycotic infection 5) due to new growth 6) general cachectic diseases 7) infection of the accessory canals of the urethra 8) due to mechanical, thermal or chemical lesion 9) due to non venereal stricture of urethra 10) reflex urethral discharge due to skin infections 11) due to physiological conditions like excessive coitus or masturbation 12) due to chronic alcoholism 13) chronic infections of prostate. The treatment advocated in NGU is a combination of streptomycin and sulphonamides for a period of three to five days. Other drugs used are flagyl, tetracycline and chloramphenicol. It is always better and advisable to avoid urethral irrigation and instillation into the urethra.

Some indigenous drugs were tried in untreated advanced lepromatous leprosy alone as well as after the preliminary Ayurvedic Regimen. The DDS was taken as the control drug against which the results obtained with the Indigenous drugs were compared after 6 months, 9 months and 1 year of treatment. In the control groups also DDS was administered alone as well as after preliminary Ayurvedic Regimen. In the assessment made at various intervals after treatment there was no indication of any appreciable improvement (clinical and bacteriological) in any of the cases. But most of the cases on indigenous drugs had gained in weight and increase in haemoglobin percent, with improvement in general condition, while most of the cases on DDS had lost in weight and decrease in haemoglobin percent without any improvement in general condition- There was no untoward effect encountered which could be attributed to the preliminary Ayurvedic Regimen and indigenous drugs. Therefore, it is advocated that the screening of the indigenous drugs, indicated in various classics of Ayurveda for the treatment of leprosy should be carried out by planned methods. The drugs which are found to be suitable can be further investigated in various insitutions for confirmation. The Ayurvedic treatment is a complex one, based on multifarious factors including the basic theories of the Science. Some preliminary preparation of the patient of Poorva-karma of the Sanshodhan (purificatory measures) is an essential pre-requisite for the adoption of any specific therapy or Pradhan-karma of leprosy. Uptill now sufficient stress has not been laid on the evaluation of this particular procedure and other ancillary measures, therefore, it is necessary to undertake specific investigations on these problems too.

Clinical and histopathological features of 21 cases of pemphigus treated as in patients are reviewed. An unusually high incidence of pemphigus in the younger age group is noted. A relatively high preponderance of the illness in persons of Blood Group B in this series is pointed out. The line of treatment followed is briefly outlined. The regime has been found to be relatively less expensive and encouragingly efficacious. The value of blood transfusions in the management is stressed.

Positive patch tests to one or more substances were demonstrated in 208 cases Out of a total of 821 tested (25.53%). The highest number of positive reactions were due to different materials used in foot wear. Kumkum dermatitis is becoming more and more common due to different new kinds of materials used in various brands of "Kumkum

A trial to evaluate the effects of tolbutamide on pigment formation in vitiligo was undertaken. Sixteen patients were treated with tolbutamide and an equal number with a placebo. Twelve cases on tolbutamide and one case on placebo developed pigment.

Forty cases of common pruritic dermatoses with or without eczematoid changes were treated with Eurax 10%-Hydrocortisone 0.25% combination. A control study group 11 was done in another forty cases of more or less identical nature with Eurax 10% alone. Eurax-hydrocortisone seems to have a remarkable effect in pruritic dermatoses with eczematoid changes. Results show that a combination of Eurax 10% hydrocortisone 0.25% (R 2040-Creme) is better than Eurax alone. Side effects were noted in one out of forty cases in group I and 4 out of 40 cases in Eurax group II.