A case of febrile, non suppurative nodular panniculitis (Weber Christian Syndrome) in a young child of 1-3/4 years is described.

A rare case of Pemphigus-vegetans is reported with a follow- up for a period of over 6 months. The termination of the condition agrees with the view expressed by others. A brief review of literatue with discussion on certain salient features as regards aetiology is appended.

About 70 trophic ulcers in leprosy have been treated with Pantophyll ointment, containing d-Pantothenyl-alcohol. The patients receive domicitiary ambulatory treatment. The dressings are done by the patients themselves. Long acting sulphas and DDS are administered. No POP is applied. Rapid re-epithelialization with gratifying results have been observed.

In this study the RPCF test, employing a specific protein antigenic fraction from the cultivable, non-pathogenic Reiter treponemes, has been evaluated and found to be relatively more "specific" than the VDRL test using the non-treponemal Cardiolipin antigen, in the diagnosis of Syphilis. It has been seen to have satisfactory "sensitivity" too even though found to be less so, than the VDRL test. These results confirm more or less in India, the findings of previous investigators in this field abroad, which has been reviewed and discussed. Therefore, the RPCF test for Syphilis is considered to be a useful diagnostic test to be introduced as supplementary to the routine VDRL test to verify and confirm the "false positive reactions" obtainable in India. It has been found to be particularly helpful in the interpretation of the significance of the reactions of the VDRL test "in low titre" that is a problem in its routine use. It is possible to prepare the specific protein antigen from the easily cultivable and available Reiter treponemes according to the standard methods described. It may be manufactured in this country conveniently at the Govt's Special Antigen Production Unit of Calcutta, along with the Cardiolipin Antigen for the VDRL test, at comparable cost and made available to all interested, in a more effective diagnosis and control of syphilis in India.

The effect of griseofulvin on a wide range of fungi was studied by a special "in vitro" technique. These included dermatophytes, saprophytic fungi as well as those fungi which are rarely reported as dermatophytes. The minimum inhibitory activity of griseofulvin on these fungi was compared. It was seen that griseofulvin has a selective inhibitory activity on susceptible dermatophytes in very low concentrations. Non-dermatopytes were resistant to the drug. The following organisms which have not hitherto been extensively studied, were also tested by the same technique: M cookei, M distortum, M nanum, T concentricum, T ferrugineum, T gallinae, T megnini, T terrestre, and K ajelloi.