IJDVL Home  
 

ORIGINAL ARTICLE
[View FULLTEXT] [Download PDF]  
Year : 2010  |  Volume : 76  |  Issue : 1  |  Page : 20-26

The effects of a daily facial lotion containing vitamins B3 and E and provitamin B5 on the facial skin of Indian women: A randomized, double-blind trial

Hemangi R Jerajani1, Haruko Mizoguchi2, James Li2, Debora J Whittenbarger2, Michael J Marmor2 
1 Department of Dermatology, L.T.M. Medical College, L.T.M. General Hospital, Mumbai, India
2 The Procter and Gamble Company, Sharon Woods Technical Center, Cincinnati, OH, USA

Correspondence Address:
Haruko Mizoguchi
The Procter and Gamble Company, Sharon Woods Technical Center, 11510 Reed Hartman Highway, Cincinnati, OH 45241-9974
USA

Background : The B vitamins niacinamide and panthenol have been shown to reduce many signs of skin aging, including hyperpigmentation and redness. Aims : To measure the facial skin effects in Indian women of the daily use of a lotion containing niacinamide, panthenol, and tocopherol acetate using quantitative image analysis. Methods : Adult women 30-60 years of age with epidermal hyperpigmentation were recruited in Mumbai and randomly assigned to apply a test or control lotion to the face daily for 10 weeks. Effects on skin tone were measured using an image capturing system and associated software. Skin texture was assessed by expert graders. Barrier function was evaluated by transepithelial water loss measurements. Subjects and evaluators were blinded to the product assignment. Results : Of 246 women randomized to treatment, 207 (84%) completed the study. Women who used the test lotion experienced significantly reduced appearance of hyperpigmentation, improved skin tone evenness, appearance of lightening of skin, and positive effects on skin texture. Improvements versus control were seen as early as 6 weeks. The test lotion was well tolerated. The most common adverse event was a transient, mild burning sensation. Conclusions : Daily use of a facial lotion containing niacinamide, panthenol, and tocopheryl acetate improved skin tone and texture and was well tolerated in Indian women with facial signs of aging.


How to cite this article:
Jerajani HR, Mizoguchi H, Li J, Whittenbarger DJ, Marmor MJ. The effects of a daily facial lotion containing vitamins B3 and E and provitamin B5 on the facial skin of Indian women: A randomized, double-blind trial.Indian J Dermatol Venereol Leprol 2010;76:20-26


How to cite this URL:
Jerajani HR, Mizoguchi H, Li J, Whittenbarger DJ, Marmor MJ. The effects of a daily facial lotion containing vitamins B3 and E and provitamin B5 on the facial skin of Indian women: A randomized, double-blind trial. Indian J Dermatol Venereol Leprol [serial online] 2010 [cited 2020 Jul 15 ];76:20-26
Available from: http://www.ijdvl.com/article.asp?issn=0378-6323;year=2010;volume=76;issue=1;spage=20;epage=26;aulast=Jerajani;type=0


 

Wednesday, July 15, 2020
 Site Map | Home | Contact Us | Feedback | Copyright and disclaimer