IJDVL Home  
 

STUDIES
[View FULLTEXT] [Download PDF]  
Year : 2003  |  Volume : 69  |  Issue : 5  |  Page : 329-333

Pulse therapy and its modifications in pemphigus: A six year study

PN Rao, TS Lakshmi 
 Department of Dermatology, Osmania Medical College, Hyderabad, India

Correspondence Address:
P N Rao
B-48, Income Tax Colony, Mehdipatnam, Hyderabad - 500 028
India

Background: Dexamethasone-cyclophosphamide pulse (DCP) therapy for the pemphigus group of disorders is being widely used in India after its introduction in 1986. However, there are certain limitations to its application due to the serious side effects of cyclophosphamide. Methods: Between 1995 and 2001, we treated 41 patients of pemphigus with modified pulse therapy. These modifications included certain changes in the DCP therapy protocol and substitution of cyclophosphamide with either azathioprine or methotrexate in a few patients. Results: We observed a good response to pulse therapy in all 34 patients who took treatment regularly. Conclusions: We found the modifications to the original DCP therapy protocol to be very effective and useful.


How to cite this article:
Rao P N, Lakshmi T S. Pulse therapy and its modifications in pemphigus: A six year study.Indian J Dermatol Venereol Leprol 2003;69:329-333


How to cite this URL:
Rao P N, Lakshmi T S. Pulse therapy and its modifications in pemphigus: A six year study. Indian J Dermatol Venereol Leprol [serial online] 2003 [cited 2019 Aug 20 ];69:329-333
Available from: http://www.ijdvl.com/article.asp?issn=0378-6323;year=2003;volume=69;issue=5;spage=329;epage=333;aulast=Rao;type=0


 

Tuesday, August 20, 2019
 Site Map | Home | Contact Us | Feedback | Copyright and disclaimer