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Year : 1995  |  Volume : 61  |  Issue : 1  |  Page : 21-25

Paucity of immune complexes in skin lesions of lichen planus

Sandipan Dhar1, Amrinder J Kanwar1, Goutam Dawn1, Shobha Sehgal2 
1 Department of Dermatology, Post-graduate Institute of Medical Education and Research, Chandigarh-160 012, India
2 Department of Venereology & Leprology and Immunopathology, Post-graduate Institute of Medical Education and Research, Chandigarh-160 012, India

Correspondence Address:
Shobha Sehgal
Department of Venereology & Leprology and Immunopathology, Post-graduate Institute of Medical Education and Research, Chandigarh-160 012
India

The significance of deposition, of immunoglobulin and/or complements at the dermoepidermal junction (DEJ) and civatte bodies in skin lesions of 15 histopathologically confirmed cases of lichen planus (LP) was evaluated. Civatte boides were seen in 6 (40%) patients while in 9 (60%) these were absent. IgM, IgG, IgA and C3 were seen within civatte bodies in 6,3, 2 and 3 specimens respectively in various combinations. LP lesions of a shorter duration (one year or less) had cjvatte bodies while these were absent in those with disease of a longer duration (more than 1 year). Immune complex deposition was seen in only 2 patients. It is concluded that civatte bodies are of diagnostic importance in lichen planus lesions of a short duration only and immune complexes do not seem to play a significant role in its pathogenesis.


How to cite this article:
Dhar S, Kanwar AJ, Dawn G, Sehgal S. Paucity of immune complexes in skin lesions of lichen planus.Indian J Dermatol Venereol Leprol 1995;61:21-25


How to cite this URL:
Dhar S, Kanwar AJ, Dawn G, Sehgal S. Paucity of immune complexes in skin lesions of lichen planus. Indian J Dermatol Venereol Leprol [serial online] 1995 [cited 2020 Jul 11 ];61:21-25
Available from: http://www.ijdvl.com/article.asp?issn=0378-6323;year=1995;volume=61;issue=1;spage=21;epage=25;aulast=Dhar;type=0


 

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