|Year : 1993 | Volume
| Issue : 1 | Page : 37-38
Spontaneous remission of primary cutaneous nocardiosis
Rama Ramani, Girij Kumari
Nocardia Brasiliensis involves the skin and subcutaneous tissue often. We report spontaneous remission of a case of primary cutaneous nocardiosis for its rarity.
|How to cite this article:|
Ramani R, Kumari G. Spontaneous remission of primary cutaneous nocardiosis.Indian J Dermatol Venereol Leprol 1993;59:37-38
|How to cite this URL:|
Ramani R, Kumari G. Spontaneous remission of primary cutaneous nocardiosis. Indian J Dermatol Venereol Leprol [serial online] 1993 [cited 2020 Jun 5 ];59:37-38
Available from: http://www.ijdvl.com/text.asp?1993/59/1/37/3878
Infection caused by Nocardia organisms are increasing in number.  Two species of Nocardia namely No. asteroides and No. brasiliensis play a major pathogenic role. No. asteroides is capable of producing a spectrum of illness involving the pulmonary system, central nervous system, and disseminated form of nocardiosis. However, No. brasiliensis frequently involves the skin and subcutaneous tissue. 
We report spontaneous healing of primary cutaneous nocardiosis in a 22-year-old man.
A 22-year-old man, agriculturist, developed skin lesions 5 years ago. To start with, the lesion was small and there was redness, oozing, and crusting. Examination revealed a linear plaque with surrounding hyperpigmentation measuring 10 cm x 4 cm on the right shin. There were no other lesions present elsewhere on the body. The haemogram, urine analysis, and chest X-ray were normal. There was no associated fever. Culture for pyogenic organisms from these lesions was sterile. A provisional diagnosis of sporotrichosis was made. The tissue was sent for fungus culture and histopathological examination. Biopsy was non- contributory, while the culture on Sabouraud's dextrose agar grew No. brasiliensis, which was confirmed by biochemical reactions. After 4 weeks the lesions resolved with hyperpigmentation.
Pustules, cellulitis, pyoderma, and lymphocutaneous form of nocardiosis are encountered.  The lymphocutaneous or sporotrichoid form of infection is an unusual form of cutaneous nocardiosis.  Starting as a local pyodermatous lesion, spreading in a linear fashion as seen in our case, mimicing the lymphocutaneous disease of Sporothrix schenckii. Most cases of cutaneous nocardial infection are associated with a predisposing condition of trivial injury, most commonly seen in gardeners.
Culture of the tissue is confirmatory as lymphocutaneous nocardiosis resembles sporotrichum infection. Nacardia organisms are susceptible to sulfonamide therapy.
However in our case, sulfonamide therapy was not given as sporotrichosis was suspected. Spontaneous remission is known in sporotrichosis  but rarely reported in nocardiosis. Immune-competence may play a role in spontaneous healing, as seen in our patient.
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